The effect of nasal steroids on retinal nerve fiber layer in patients with a family history of glaucoma

Mehmet Tahir Eski; İlhan Ünlü

Makale detayları

The effect of nasal steroids on retinal nerve fiber layer in patients with a family history of glaucoma

Yazarlar:

Mehmet Tahir Eski | İlhan Ünlü

Yayıncı:

Prusa Medical Publishing

Ana Başlıklar:

Ophthalmology

Dergi:

The European Research Journal Vol.9 Issue 2, pp.222-230

Belge Tipi:

Makale

Yayın Tarihi:

4/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001282996

pISSN:

2149-3189

Anahtar kelimeler:

Özet:

 Objectives: We aimed at analyzing the effect of nasal steroids on intraocular pressure IOP and retinal nerve fiber layer thickness RNFL in patients with a family history of glaucoma who also use fluticasone propionate FP group and mometasone furoate MF group. Methods: Patients with a family history of glaucoma and suitable for using nasal steroids were included in the study population. IOP, anterior chamber depth ACD, axial length AL and central corneal thickness CCT and RNFL thickness measurements of the patients were carried out. Measurements were done on 3 levels, namely, one before starting the medication, the other 1 month after starting the medication and the last one 3 months after the medication. 3 groups were established in our study: patients who are using MF group and FP group and also C group control group; healthy individuals who have a family history of glaucoma but not using any medication. Results: The average age of patients in our study who were under medication was 33.2  8.9 years. The study consisted of a total of 46 patients, 32 of whom were using nasal steroids and 14 belonging to the C group. It was found that global value in MF group decreased from 100.9  7.7 to 99.6  7.6 in the 3 rd month and ACD in MF group decreased from 3.2  0.4 mm to 2.9  0.4 mm in the 1 st month, both to be found statistically significant  p  0.037 and p  0.001 respectively. During the RNFL thickness measurements of patients, it was found that Temporal T segment in FP group decreased from 82.1  13.8 to 81.7  13.3 in the first month and T segment in MF group decreased from 72.8  12.0 to 71.3  10.2 in 3 months, both decreases to be found statistically significant  p  0.047 and p0.003 respectively. It was found that IOP in FP group increased from 15.3  3.6 mm Hg to 17.7  4.1 mm Hg in the 3 rd month hence found to be statistically significant  p  0.006. CCT in FP patients was found to be significantly higher in the 3 rd month  p  0.025. Conclusions: As a result of our study, it was found that nasal steroid usage in patients with a family history of glaucoma may cause an increase in IOP and thinning of the RNFL.

 Objectives: We aimed at analyzing the effect of nasal steroids on intraocular pressure IOP and retinal nerve fiber layer thickness RNFL in patients with a family history of glaucoma who also use fluticasone propionate FP group and mometasone furoate MF group. Methods: Patients with a family history of glaucoma and suitable for using nasal steroids were included in the study population. IOP, anterior chamber depth ACD, axial length AL and central corneal thickness CCT and RNFL thickness measurements of the patients were carried out. Measurements were done on 3 levels, namely, one before starting the medication, the other 1 month after starting the medication and the last one 3 months after the medication. 3 groups were established in our study: patients who are using MF group and FP group and also C group control group; healthy individuals who have a family history of glaucoma but not using any medication. Results: The average age of patients in our study who were under medication was 33.2  8.9 years. The study consisted of a total of 46 patients, 32 of whom were using nasal steroids and 14 belonging to the C group. It was found that global value in MF group decreased from 100.9  7.7 to 99.6  7.6 in the 3 rd month and ACD in MF group decreased from 3.2  0.4 mm to 2.9  0.4 mm in the 1 st month, both to be found statistically significant  p  0.037 and p  0.001 respectively. During the RNFL thickness measurements of patients, it was found that Temporal T segment in FP group decreased from 82.1  13.8 to 81.7  13.3 in the first month and T segment in MF group decreased from 72.8  12.0 to 71.3  10.2 in 3 months, both decreases to be found statistically significant  p  0.047 and p0.003 respectively. It was found that IOP in FP group increased from 15.3  3.6 mm Hg to 17.7  4.1 mm Hg in the 3 rd month hence found to be statistically significant  p  0.006. CCT in FP patients was found to be significantly higher in the 3 rd month  p  0.025. Conclusions: As a result of our study, it was found that nasal steroid usage in patients with a family history of glaucoma may cause an increase in IOP and thinning of the RNFL.

 Objectives: We aimed at analyzing the effect of nasal steroids on intraocular pressure IOP and retinal nerve fiber layer thickness RNFL in patients with a family history of glaucoma who also use fluticasone propionate FP group and mometasone furoate MF group. Methods: Patients with a family history of glaucoma and suitable for using nasal steroids were included in the study population. IOP, anterior chamber depth ACD, axial length AL and central corneal thickness CCT and RNFL thickness measurements of the patients were carried out. Measurements were done on 3 levels, namely, one before starting the medication, the other 1 month after starting the medication and the last one 3 months after the medication. 3 groups were established in our study: patients who are using MF group and FP group and also C group control group; healthy individuals who have a family history of glaucoma but not using any medication. Results: The average age of patients in our study who were under medication was 33.2  8.9 years. The study consisted of a total of 46 patients, 32 of whom were using nasal steroids and 14 belonging to the C group. It was found that global value in MF group decreased from 100.9  7.7 to 99.6  7.6 in the 3 rd month and ACD in MF group decreased from 3.2  0.4 mm to 2.9  0.4 mm in the 1 st month, both to be found statistically significant  p  0.037 and p  0.001 respectively. During the RNFL thickness measurements of patients, it was found that Temporal T segment in FP group decreased from 82.1  13.8 to 81.7  13.3 in the first month and T segment in MF group decreased from 72.8  12.0 to 71.3  10.2 in 3 months, both decreases to be found statistically significant  p  0.047 and p0.003 respectively. It was found that IOP in FP group increased from 15.3  3.6 mm Hg to 17.7  4.1 mm Hg in the 3 rd month hence found to be statistically significant  p  0.006. CCT in FP patients was found to be significantly higher in the 3 rd month  p  0.025. Conclusions: As a result of our study, it was found that nasal steroid usage in patients with a family history of glaucoma may cause an increase in IOP and thinning of the RNFL.

 Objectives: We aimed at analyzing the effect of nasal steroids on intraocular pressure IOP and retinal nerve fiber layer thickness RNFL in patients with a family history of glaucoma who also use fluticasone propionate FP group and mometasone furoate MF group. Methods: Patients with a family history of glaucoma and suitable for using nasal steroids were included in the study population. IOP, anterior chamber depth ACD, axial length AL and central corneal thickness CCT and RNFL thickness measurements of the patients were carried out. Measurements were done on 3 levels, namely, one before starting the medication, the other 1 month after starting the medication and the last one 3 months after the medication. 3 groups were established in our study: patients who are using MF group and FP group and also C group control group; healthy individuals who have a family history of glaucoma but not using any medication. Results: The average age of patients in our study who were under medication was 33.2  8.9 years. The study consisted of a total of 46 patients, 32 of whom were using nasal steroids and 14 belonging to the C group. It was found that global value in MF group decreased from 100.9  7.7 to 99.6  7.6 in the 3 rd month and ACD in MF group decreased from 3.2  0.4 mm to 2.9  0.4 mm in the 1 st month, both to be found statistically significant  p  0.037 and p  0.001 respectively. During the RNFL thickness measurements of patients, it was found that Temporal T segment in FP group decreased from 82.1  13.8 to 81.7  13.3 in the first month and T segment in MF group decreased from 72.8  12.0 to 71.3  10.2 in 3 months, both decreases to be found statistically significant  p  0.047 and p0.003 respectively. It was found that IOP in FP group increased from 15.3  3.6 mm Hg to 17.7  4.1 mm Hg in the 3 rd month hence found to be statistically significant  p  0.006. CCT in FP patients was found to be significantly higher in the 3 rd month  p  0.025. Conclusions: As a result of our study, it was found that nasal steroid usage in patients with a family history of glaucoma may cause an increase in IOP and thinning of the RNFL.

Makale detayları

The effect of nasal steroids on retinal nerve fiber layer in patients with a family history of glaucoma

Yazarlar:

Mehmet Tahir Eski | İlhan Ünlü

Yayıncı:

Prusa Medical Publishing

Ana Başlıklar:

Ophthalmology

Dergi:

The European Research Journal Vol.9 Issue 2, pp.222-230

Belge Tipi:

Makale

Yayın Tarihi:

4/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001282996

pISSN:

2149-3189

Mometasone furoate

fluticasone propionate

intraocular pressure

retinal nerve fiber layer thickness

Sayı

Makale detayları

The effect of nasal steroids on retinal nerve fiber layer in patients with a family history of glaucoma

Yazarlar: Mehmet Tahir Eski | İlhan Ünlü

Yayıncı: Prusa Medical Publishing

Ana Başlıklar: Ophthalmology

Dergi: The European Research Journal Vol.9 Issue 2, pp.222-230

Belge Tipi: Makale

Yayın Tarihi: 4/2023

Belge Dili: İngilizce

Document ID (Org No.): 2001282996

pISSN: 2149-3189

Mometasone furoate

fluticasone propionate

intraocular pressure

retinal nerve fiber layer thickness

Sayı

Yazarlar:

Mehmet Tahir Eski | İlhan Ünlü

Yayıncı:

Prusa Medical Publishing

Ana Başlıklar:

Ophthalmology

Dergi:

The European Research Journal Vol.9 Issue 2, pp.222-230

Belge Tipi:

Makale

Yayın Tarihi:

4/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001282996

pISSN:

2149-3189