The Value Of Ultra-Sensitive Troponin-I In Determining Mortality In Patients With Suspected Acute Coronary Syndrome

Çeral Efe Aracı; Murat Duyan; Mutlu Kartal; Erkan Göksu

Makale detayları

The Value Of Ultra-Sensitive Troponin-I In Determining Mortality In Patients With Suspected Acute Coronary Syndrome

Yazarlar:

Çeral Efe Aracı | Murat Duyan | Mutlu Kartal | Erkan Göksu

Yayıncı:

Akdeniz University

Ana Başlıklar:

Klinik Tıp Bilimleri

Dergi:

Akdeniz Tıp Dergisi Vol.9 Issue 3, pp.265-270

Belge Tipi:

Makale

Yayın Tarihi:

1/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001294276

pISSN:

2687-2781

Anahtar kelimeler:

Özet:

 Abstract: Objective: This study investigated the role of the reference value of ultra-sensitive troponin kits used in daily practice in determining mortality. Material-methods: This study was conducted in the emergency department ED of Akdeniz University Hospital between January 1, 2018, and June 30, 2019. All patients admitted to the emergency department within a period of eighteen months and who had the result of the ultra-sensitive troponin level in the range of 0.06-0.1 ngmL were included in the study. The recurrent admissions of the patients to the ED were included, and only the first troponin values of the patients were taken as s reference for the study. Result: It was determined that 1029 troponin values of 591 patients with initial troponin I value in the range 0.06-0.1 ngmL were measured. It was found that 332 of these patients were discharged from the emergency department, and the others were hospitalized. It was found that 168 28.43 of the patients died. Considering the gender distribution of the patients who died, it was observed that 101 60.11 patients were male, and 67 39.89 patients were female. A statistically significant difference was found between the ages of the patients who died mean 71.3812.25 and the age of patients alive mean 61.78  15.89 p 0.019. In univariate analysis, in addition to the positive troponin value, DM p0.022 and hyperlipidemia p0.018 were found to be statistically significant. Conclusion: For high-sensitive troponin worked in the ED, the upper value of 0.06 ngmL effectively determines mortality.

 Abstract: Objective: This study investigated the role of the reference value of ultra-sensitive troponin kits used in daily practice in determining mortality. Material-methods: This study was conducted in the emergency department ED of Akdeniz University Hospital between January 1, 2018, and June 30, 2019. All patients admitted to the emergency department within a period of eighteen months and who had the result of the ultra-sensitive troponin level in the range of 0.06-0.1 ngmL were included in the study. The recurrent admissions of the patients to the ED were included, and only the first troponin values of the patients were taken as s reference for the study. Result: It was determined that 1029 troponin values of 591 patients with initial troponin I value in the range 0.06-0.1 ngmL were measured. It was found that 332 of these patients were discharged from the emergency department, and the others were hospitalized. It was found that 168 28.43 of the patients died. Considering the gender distribution of the patients who died, it was observed that 101 60.11 patients were male, and 67 39.89 patients were female. A statistically significant difference was found between the ages of the patients who died mean 71.3812.25 and the age of patients alive mean 61.78  15.89 p 0.019. In univariate analysis, in addition to the positive troponin value, DM p0.022 and hyperlipidemia p0.018 were found to be statistically significant. Conclusion: For high-sensitive troponin worked in the ED, the upper value of 0.06 ngmL effectively determines mortality.

 Abstract: Objective: This study investigated the role of the reference value of ultra-sensitive troponin kits used in daily practice in determining mortality. Material-methods: This study was conducted in the emergency department ED of Akdeniz University Hospital between January 1, 2018, and June 30, 2019. All patients admitted to the emergency department within a period of eighteen months and who had the result of the ultra-sensitive troponin level in the range of 0.06-0.1 ngmL were included in the study. The recurrent admissions of the patients to the ED were included, and only the first troponin values of the patients were taken as s reference for the study. Result: It was determined that 1029 troponin values of 591 patients with initial troponin I value in the range 0.06-0.1 ngmL were measured. It was found that 332 of these patients were discharged from the emergency department, and the others were hospitalized. It was found that 168 28.43 of the patients died. Considering the gender distribution of the patients who died, it was observed that 101 60.11 patients were male, and 67 39.89 patients were female. A statistically significant difference was found between the ages of the patients who died mean 71.3812.25 and the age of patients alive mean 61.78  15.89 p 0.019. In univariate analysis, in addition to the positive troponin value, DM p0.022 and hyperlipidemia p0.018 were found to be statistically significant. Conclusion: For high-sensitive troponin worked in the ED, the upper value of 0.06 ngmL effectively determines mortality.

 özet: Amaç: Bu çalışmada, günlük pratikte kullanılan ultra-duyarlı troponin kitlerinin referans değerinin mortaliteyi belirlemedeki rolünü araştırıldı. Gereç-yöntem: Bu çalışma 1 Ocak 2018-30 Haziran 2019 tarihleri arasında Akdeniz Üniversitesi Hastanesi acil servisinde AS yapılmıştır. Acil servise on sekiz ay içinde başvuran ve sonucu olan tüm hastalar 0.06-0.1 ngmL aralığındaki ultra-duyarlı troponin düzeyi çalışmaya dahil edildi. Hastaların acil servise tekrarlayan başvuruları dahil edildi ve hastaların sadece ilk troponin değerleri çalışma için referans olarak alındı. Bulgular: Başlangıç troponin I değeri 0.06-0.1 ngmL aralığında olan 591 hastanın 1029 troponin değerinin ölçüldüğü belirlendi. Bu hastalardan 332sinin acil servisten taburcu edildiği, diğerlerinin ise hastaneye kaldırıldığı öğrenildi. Hastaların 168inin 28,43 öldüğü belirlendi. Ölen hastaların cinsiyet dağılımına bakıldığında 101 60,11 hastanın erkek, 67 39,89 hastanın kadın olduğu görüldü. Ölen hastaların yaşları ortalama 71.3812.25 ile yaşayan hastaların yaşları ortalama 61.7815.89 arasında istatistiksel olarak anlamlı fark bulundu p0.019. Tek değişkenli analizde pozitif troponin değerine ek olarak DM p0.022 ve hiperlipidemi p0.018 istatistiksel olarak anlamlı bulundu. Sonuç: Acil serviste çalışılan yüksek duyarlı troponin için 0.06 ngmLlik üst değer etkin bir şekilde mortaliteyi belirler.

Makale detayları

The Value Of Ultra-Sensitive Troponin-I In Determining Mortality In Patients With Suspected Acute Coronary Syndrome

Yazarlar:

Çeral Efe Aracı | Murat Duyan | Mutlu Kartal | Erkan Göksu

Yayıncı:

Akdeniz University

Ana Başlıklar:

Klinik Tıp Bilimleri

Dergi:

Akdeniz Tıp Dergisi Vol.9 Issue 3, pp.265-270

Belge Tipi:

Makale

Yayın Tarihi:

1/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001294276

pISSN:

2687-2781

Ultra-Sensitive Troponin-I

mortality

acute coronary syndromeUltra-Sensitive Troponin-I

mortalite

akut koroner sendrom

Sayı

Makale detayları

The Value Of Ultra-Sensitive Troponin-I In Determining Mortality In Patients With Suspected Acute Coronary Syndrome

Yazarlar: Çeral Efe Aracı | Murat Duyan | Mutlu Kartal | Erkan Göksu

Yayıncı: Akdeniz University

Ana Başlıklar: Klinik Tıp Bilimleri

Dergi: Akdeniz Tıp Dergisi Vol.9 Issue 3, pp.265-270

Belge Tipi: Makale

Yayın Tarihi: 1/2023

Belge Dili: İngilizce

Document ID (Org No.): 2001294276

pISSN: 2687-2781

Ultra-Sensitive Troponin-I

mortality

acute coronary syndromeUltra-Sensitive Troponin-I

mortalite

akut koroner sendrom

Sayı

Yazarlar:

Çeral Efe Aracı | Murat Duyan | Mutlu Kartal | Erkan Göksu

Yayıncı:

Akdeniz University

Ana Başlıklar:

Klinik Tıp Bilimleri

Dergi:

Akdeniz Tıp Dergisi Vol.9 Issue 3, pp.265-270

Belge Tipi:

Makale

Yayın Tarihi:

1/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001294276

pISSN:

2687-2781