PROLIDASE LEVEL IN CORONARY ARTERY DISEASE AND ISCHEMIC  MITRAL VALVE INSUFFICIENCY

Vedat Ağrıç; Mustafa Göz; Reşat Dikme; Mahmut Padak; Mehmet Salih Aydın; Nazım Kankılıç; Bişar Amaç

Makale detayları

PROLIDASE LEVEL IN CORONARY ARTERY DISEASE AND ISCHEMIC MITRAL VALVE INSUFFICIENCY

Yazarlar:

Vedat Ağrıç | Mustafa Göz | Reşat Dikme | Mahmut Padak | Mehmet Salih Aydın | Nazım Kankılıç | Bişar Amaç

Yayıncı:

Inonu University

Ana Başlıklar:

Klinik Tıp Bilimleri

Dergi:

İnönü Üniversitesi Sağlık Hizmetleri Meslek Yüksek Okulu Dergisi Vol.11 Issue 2, pp.1499-1506

Belge Tipi:

Makale

Yayın Tarihi:

10/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001290067

pISSN:

2147-7892

Anahtar kelimeler:

Özet:

 Plasma prolidase levels change as a determining factor for coronary artery disease and heart valve insufficiency. The aim of this study is to compare plasma prolidase levels in two groups with or without mitral regurgitation who underwent coronary artery bypass surgery CABS. For this purpose, 45 patients who underwent CABS were included in the study; patients without mitral valve insufficiency who underwent CABS 25 patients Group 1, patients with mitral valve insufficiency who underwent CABS 20 patients Group 2. Venous blood was taken from all patients before and after CABS and their prolidase levels were measured. Preoperative and postoperative serum prolidase levels in group 1 were 1038.2 and 1289.43 UL, respectively. In group 2, preoperative and postoperative serum prolidase levels were 1084.07 and 1337.74 UL, respectively. A significant difference was found between preoperative and postoperative plasma prolidase levels of Group 1 and Group 2 included in the study p0.05. Plasma prolidase level was high in both groups. However, pre- and postoperative serum prolidase levels were found to be higher in patients with mitral valve insufficiency in Group 2. In conclusion, in this study, it was determined that the plasma prolidase level was higher in patients with mitral valve insufficiency who underwent CABS.

 Plasma prolidase levels change as a determining factor for coronary artery disease and heart valve insufficiency. The aim of this study is to compare plasma prolidase levels in two groups with or without mitral regurgitation who underwent coronary artery bypass surgery CABS. For this purpose, 45 patients who underwent CABS were included in the study; patients without mitral valve insufficiency who underwent CABS 25 patients Group 1, patients with mitral valve insufficiency who underwent CABS 20 patients Group 2. Venous blood was taken from all patients before and after CABS and their prolidase levels were measured. Preoperative and postoperative serum prolidase levels in group 1 were 1038.2 and 1289.43 UL, respectively. In group 2, preoperative and postoperative serum prolidase levels were 1084.07 and 1337.74 UL, respectively. A significant difference was found between preoperative and postoperative plasma prolidase levels of Group 1 and Group 2 included in the study p0.05. Plasma prolidase level was high in both groups. However, pre- and postoperative serum prolidase levels were found to be higher in patients with mitral valve insufficiency in Group 2. In conclusion, in this study, it was determined that the plasma prolidase level was higher in patients with mitral valve insufficiency who underwent CABS.

 Plasma prolidase levels change as a determining factor for coronary artery disease and heart valve insufficiency. The aim of this study is to compare plasma prolidase levels in two groups with or without mitral regurgitation who underwent coronary artery bypass surgery CABS. For this purpose, 45 patients who underwent CABS were included in the study; patients without mitral valve insufficiency who underwent CABS 25 patients Group 1, patients with mitral valve insufficiency who underwent CABS 20 patients Group 2. Venous blood was taken from all patients before and after CABS and their prolidase levels were measured. Preoperative and postoperative serum prolidase levels in group 1 were 1038.2 and 1289.43 UL, respectively. In group 2, preoperative and postoperative serum prolidase levels were 1084.07 and 1337.74 UL, respectively. A significant difference was found between preoperative and postoperative plasma prolidase levels of Group 1 and Group 2 included in the study p0.05. Plasma prolidase level was high in both groups. However, pre- and postoperative serum prolidase levels were found to be higher in patients with mitral valve insufficiency in Group 2. In conclusion, in this study, it was determined that the plasma prolidase level was higher in patients with mitral valve insufficiency who underwent CABS.

 Plazma prolidaz seviyeleri, koroner arter hastalığı ve kalp kapağı yetmezliği için belirleyici bir faktör olarak değişir. Bu çalışmanın amacı mitral yetersizliği olan ve olmayan koroner arter baypas cerrahisi KABC uygulanan iki grupta plazma prolidaz düzeylerini karşılaştırmaktır. Bu amaçla çalışmaya KABC uygulanan 45 hasta dâhil edildi; mitral kapak yetmezliği olmayan ve KABC uygulanan hastalar 25 hasta Grup 1, mitral kapak yetmezliği olup KABC uygulanan hastalar 20 hasta Grup 2 olarak adlandırıldı. Tüm hastalardan KABC öncesi ve sonrası venöz kan alındı ve prolidaz düzeyleri ölçüldü. Grup 1de preoperatif ve postoperatif serum prolidaz seviyeleri sırasıyla 1038.2 ve 1289.43 UL olarak hesaplandı. Grup 2de ise preoperatif ve postoperatif serum prolidaz seviyeleri sırasıyla 1084,07 ve 1337.74 UL olarak hesaplandı. Çalışmaya alınan Grup 1 ve Grup 2nin preoperatif ve postoperatif plazma prolidaz düzeyleri arasında anlamlı fark bulundu p0.05. Plazma prolidaz düzeyi her iki grupta da yüksekti. Ancak Grup 2de mitral kapak yetmezliği olan hastalarda ameliyat öncesi ve sonrası serum prolidaz düzeyleri daha yüksek bulundu. Sonuç olarak bu çalışmada mitral kapak yetersizliği nedeniyle KABC yapılan hastalarda plazma prolidaz düzeyinin daha yüksek olduğu belirlendi.

Makale detayları

PROLIDASE LEVEL IN CORONARY ARTERY DISEASE AND ISCHEMIC MITRAL VALVE INSUFFICIENCY

Yazarlar:

Vedat Ağrıç | Mustafa Göz | Reşat Dikme | Mahmut Padak | Mehmet Salih Aydın | Nazım Kankılıç | Bişar Amaç

Yayıncı:

Inonu University

Ana Başlıklar:

Klinik Tıp Bilimleri

Dergi:

İnönü Üniversitesi Sağlık Hizmetleri Meslek Yüksek Okulu Dergisi Vol.11 Issue 2, pp.1499-1506

Belge Tipi:

Makale

Yayın Tarihi:

10/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001290067

pISSN:

2147-7892

Cardiopulmonary bypass

Coronary bypass surgery

Ischemic mitral regurgitation

Mitral valve insufficiency

Prolidaseİskemik mitral yetmezlik

Kardiyopulmoner baypas

Koroner baypas cerrahisi

Mitral kapak yetmezliği

Prolidaz

Sayı

Makale detayları

Yazarlar: Vedat Ağrıç | Mustafa Göz | Reşat Dikme | Mahmut Padak | Mehmet Salih Aydın | Nazım Kankılıç | Bişar Amaç

Yayıncı: Inonu University

Ana Başlıklar: Klinik Tıp Bilimleri

Dergi: İnönü Üniversitesi Sağlık Hizmetleri Meslek Yüksek Okulu Dergisi Vol.11 Issue 2, pp.1499-1506

Belge Tipi: Makale

Yayın Tarihi: 10/2023

Belge Dili: İngilizce

Document ID (Org No.): 2001290067

pISSN: 2147-7892

Sayı

Yazarlar:

Vedat Ağrıç | Mustafa Göz | Reşat Dikme | Mahmut Padak | Mehmet Salih Aydın | Nazım Kankılıç | Bişar Amaç

Yayıncı:

Inonu University

Ana Başlıklar:

Klinik Tıp Bilimleri

Dergi:

İnönü Üniversitesi Sağlık Hizmetleri Meslek Yüksek Okulu Dergisi Vol.11 Issue 2, pp.1499-1506

Belge Tipi:

Makale

Yayın Tarihi:

10/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001290067

pISSN:

2147-7892