Unusual infections in resected adenoid of children: PCR for C. pneumonia, M. pneumonia, H. pylori.

Mohammad FARHADİ; Samileh NOORBAKHSH; Farideh Ebrahimi TAJ; Naser JAVAHERTRASH; Azardokht TABATABAEİ; Masomeh BAKHSHYEH

Makale detayları

Unusual infections in resected adenoid of children: PCR for C. pneumonia, M. pneumonia, H. pylori.

Yazarlar:

Mohammad FARHADİ | Samileh NOORBAKHSH | Farideh Ebrahimi TAJ | Naser JAVAHERTRASH | Azardokht TABATABAEİ | Masomeh BAKHSHYEH

Yayıncı:

Van Yuzuncu Yıl University

Dergi:

EASTERN JOURNAL OF MEDICINE 2011 Vol.16 Issue 1, pp.32-38

Belge Tipi:

Makale

Yayın Tarihi:

1/2013

Belge Dili:

İngilizce

Document ID (Org No.):

2000773015

Sıklık:

Aylık

eISSN:

1301-0883

pISSN:

1301-0883

Özet:

 


Abstract. Recurrent or chronic adenotonsillar infections mainly affect children.The possible role for infectious agents in adenoid hypertrophy have reported. Searching the DNAs (PCR) of M. pneumonia, C. pneumonia and H. pylori in resected adenoid of children with adenoid surgery. A cross-sectional study done in ENT and Pediatric Department of Rasul Akram Hospital during 2006-2008. 53 children with recurrent or chronic adenotonsillar infections candidate for adenoid surgery were selected .The resected adenoid tissues (1cm) during surgery removed by surgeon. The tissue samples were centrifuged and homogenized, DNAs were extracted and searched for DNAs of M. pneumonia, C. pneumonia and H. pylori by qualitative PCR. Mean age of cases was 8 ±1.9 years. 48% male; 51.9% female 23%. Most cases aged between 6-9 years (71.5%). Most adenoid surgery was done in winter (32%). M. pneumonia- DNA detected in 28%; C. pneumonia in 13.2%; H. pylori in 15% of tissue samples with no relation to   sex and age of cases. Most positive PCR results for C. pneumonia and H. pylori (p=0.05; 0.02) were seen in spring and summer but not for M. pneumonia ( p=0.5) We could detect at least 1 of these 3 unusual infectious agents (M. pneumonia, C. pneumonia and H. Pylori) in adenoid tissues of 60% cases. These unusual infections may have a relative role in etiology of adenoid hypertrophy. Chronic sinusitis and ear infection might be added to infected adenoid tissue as a reservoir for these unusual bacteria. The search by more specific method such as Real time-PCR; or specific culture may elucidate better the role of these unusual infections in adenoid hypertrophy in future. The decision for use of antibiotics to eradicate these unusual infections in recurrent or chronic adenotonsillar infections before adenoid surgery (with or without rhinosinusitis or chronic ear infection) needs Randomized Controlled Trial studies.

Key words: Adenoid tissue; Adenoid hypertrophy; C. pneumonia; M. pneumonia; H. pylori  

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Makale detayları

Unusual infections in resected adenoid of children: PCR for C. pneumonia, M. pneumonia, H. pylori.

Yazarlar: Mohammad FARHADİ | Samileh NOORBAKHSH | Farideh Ebrahimi TAJ | Naser JAVAHERTRASH | Azardokht TABATABAEİ | Masomeh BAKHSHYEH

Yayıncı: Van Yuzuncu Yıl University

Dergi: EASTERN JOURNAL OF MEDICINE 2011 Vol.16 Issue 1, pp.32-38

Belge Tipi: Makale

Yayın Tarihi: 1/2013

Belge Dili: İngilizce

Document ID (Org No.): 2000773015

Sıklık: Aylık

eISSN: 1301-0883

pISSN: 1301-0883

Sayı

Yazarlar:

Mohammad FARHADİ | Samileh NOORBAKHSH | Farideh Ebrahimi TAJ | Naser JAVAHERTRASH | Azardokht TABATABAEİ | Masomeh BAKHSHYEH

Yayıncı:

Van Yuzuncu Yıl University

Dergi:

EASTERN JOURNAL OF MEDICINE 2011 Vol.16 Issue 1, pp.32-38

Belge Tipi:

Makale

Yayın Tarihi:

1/2013

Belge Dili:

İngilizce

Document ID (Org No.):

2000773015

Sıklık:

Aylık

eISSN:

1301-0883

pISSN:

1301-0883