The Role of Royal Jelly on Exhaustive Exercise-Induced Oxidative Stress

Murat Bakır

Makale detayları

The Role of Royal Jelly on Exhaustive Exercise-Induced Oxidative Stress

Yazarlar:

Murat Bakır

Yayıncı:

Bingol University

Ana Başlıklar:

Sağlık Kurumları Yönetimi

Dergi:

Türk Doğa ve Fen Dergisi Vol.12 Issue 2, pp.1-7

Belge Tipi:

Makale

Yayın Tarihi:

6/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001292404

pISSN:

2149-6366

Anahtar kelimeler:

Özet:

 In this study, the effects of Royal Jelly RJ on oxidative stress caused by exhaustive swimming exercise in rat tissues were evaluated. Methods: Twenty four male Wistar albino rats were indiscriminately distributed into four experimental groups: Sedentary control SC; SC with administration of RJ 100 mg kg-1 SC  RJ; exhaustive swimming exercise E; Exhaustive swimming exercise with administration of RJ 100 mg kg-1 E  RJ. 100 mg kg-1 of RJ were dissolved in drinking water. Rats in the SCRJ and ERJ groups supplemented with RJ 100 mg kg-1 orally once a day for two weeks. Rats in groups E and ERJ subjected to acute exhaustive swimming exercise on the 14th day of the study, then some biochemical parameters related to oxidative stress of all groups were measured. Results: The activities of alanine aminotransferase ALT, aspartate aminotransferase AST, alkaline phosphatase ALP, blood urea nitrogen BUN and creatinine CRE levels significantly raised in the exercised rats compared with the sedentary rats P  0.05. The decreased superoxide dismutase SOD, glutathione peroxidase GSHPx, and catalase CAT activities of muscular and hepatic tissues significantly increased and the high malondialdehyde MDA levels of muscular, hepatic and kidney tissues significantly reduced in exercised rats treated with RJ P  0.05. Conclucion: Collectively, in this study, protective effects of RJ on tissues against oxidative damage after exhaustive exercise were observed.

 In this study, the effects of Royal Jelly RJ on oxidative stress caused by exhaustive swimming exercise in rat tissues were evaluated. Methods: Twenty four male Wistar albino rats were indiscriminately distributed into four experimental groups: Sedentary control SC; SC with administration of RJ 100 mg kg-1 SC  RJ; exhaustive swimming exercise E; Exhaustive swimming exercise with administration of RJ 100 mg kg-1 E  RJ. 100 mg kg-1 of RJ were dissolved in drinking water. Rats in the SCRJ and ERJ groups supplemented with RJ 100 mg kg-1 orally once a day for two weeks. Rats in groups E and ERJ subjected to acute exhaustive swimming exercise on the 14th day of the study, then some biochemical parameters related to oxidative stress of all groups were measured. Results: The activities of alanine aminotransferase ALT, aspartate aminotransferase AST, alkaline phosphatase ALP, blood urea nitrogen BUN and creatinine CRE levels significantly raised in the exercised rats compared with the sedentary rats P  0.05. The decreased superoxide dismutase SOD, glutathione peroxidase GSHPx, and catalase CAT activities of muscular and hepatic tissues significantly increased and the high malondialdehyde MDA levels of muscular, hepatic and kidney tissues significantly reduced in exercised rats treated with RJ P  0.05. Conclucion: Collectively, in this study, protective effects of RJ on tissues against oxidative damage after exhaustive exercise were observed.

 In this study, the effects of Royal Jelly RJ on oxidative stress caused by exhaustive swimming exercise in rat tissues were evaluated. Methods: Twenty four male Wistar albino rats were indiscriminately distributed into four experimental groups: Sedentary control SC; SC with administration of RJ 100 mg kg-1 SC  RJ; exhaustive swimming exercise E; Exhaustive swimming exercise with administration of RJ 100 mg kg-1 E  RJ. 100 mg kg-1 of RJ were dissolved in drinking water. Rats in the SCRJ and ERJ groups supplemented with RJ 100 mg kg-1 orally once a day for two weeks. Rats in groups E and ERJ subjected to acute exhaustive swimming exercise on the 14th day of the study, then some biochemical parameters related to oxidative stress of all groups were measured. Results: The activities of alanine aminotransferase ALT, aspartate aminotransferase AST, alkaline phosphatase ALP, blood urea nitrogen BUN and creatinine CRE levels significantly raised in the exercised rats compared with the sedentary rats P  0.05. The decreased superoxide dismutase SOD, glutathione peroxidase GSHPx, and catalase CAT activities of muscular and hepatic tissues significantly increased and the high malondialdehyde MDA levels of muscular, hepatic and kidney tissues significantly reduced in exercised rats treated with RJ P  0.05. Conclucion: Collectively, in this study, protective effects of RJ on tissues against oxidative damage after exhaustive exercise were observed.

 Bu çalışmada, Arı Sütü RJnin sıçan dokularındaki tüketici yüzme egzersizinin neden olduğu oksidatif stres üzerindeki etkileri değerlendirildi. Metodlar: Yirmi dört adet erkek Wistar albino sıçan rastgele dört deney grubuna ayrıldı: Sedanter kontrol SC; 100 mg kg-1 RJ uygulanmış SC SC  RJ; tüketici yüzme egzersiz grubu E; 100 mg kg-1 RJ uygulanmış tüketici yüzme egzersiz grubu E  RJ. 100 mg kg-1 RJ içme suyunda çözüldü. SC  RJ ve E  RJ gruplarındaki sıçanlara, iki hafta boyunca günde bir kez ağızdan RJ 100 mg kg-1 verildi. E ve E  RJ gruplarındaki sıçanlar çalışmanın 14. gününde akut tüketici yüzme egzersizine tabi tutulduktan sonra tüm grupların oksidatif stres ile ilgili bazı biyokimyasal parametreleri ölçüldü. Bulgular: Alanin aminotransferaz ALT, aspartat aminotransferaz AST, alkalin fosfataz ALP, kan üre azotu BUN ve kreatinin CRE seviyelerinin aktiviteleri, egzersiz yapılan sıçanlarda, sedanter sıçanlara kıyasla önemli ölçüde artmıştır P  0.05. RJ ile tedavi edilen sıçanlarda kas ve hepatik dokuların azalmış süperoksit dismutaz SOD, glutatyon peroksidaz GSHPx ve katalaz CAT aktiviteleri önemli ölçüde artmış ve kas, hepatik ve böbrek dokularının yüksek malondialdehit MDA seviyeleri önemli ölçüde azalmıştır P  0.05. Sonuç: Sonuç olarak, bu çalışmada, tüketici egzersiz sonrası oluşan dokular üzerindeki oksidatif hasara karşı RJnin koruyucu etkileri gözlenmiştir.

Makale detayları

The Role of Royal Jelly on Exhaustive Exercise-Induced Oxidative Stress

Yazarlar:

Murat Bakır

Yayıncı:

Bingol University

Ana Başlıklar:

Sağlık Kurumları Yönetimi

Dergi:

Türk Doğa ve Fen Dergisi Vol.12 Issue 2, pp.1-7

Belge Tipi:

Makale

Yayın Tarihi:

6/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001292404

pISSN:

2149-6366

Royal Jelly

Liver

Kidney

Skeletal muscle

Exhaustive exercise

AntioxidantArı sütü

Karaciğer

Böbrek

İskelet kası

Tüketici egzersiz

Antioksidan

Sayı

Makale detayları

Yazarlar: Murat Bakır

Yayıncı: Bingol University

Ana Başlıklar: Sağlık Kurumları Yönetimi

Dergi: Türk Doğa ve Fen Dergisi Vol.12 Issue 2, pp.1-7

Belge Tipi: Makale

Yayın Tarihi: 6/2023

Belge Dili: İngilizce

Document ID (Org No.): 2001292404

pISSN: 2149-6366

Sayı

Yazarlar:

Murat Bakır

Yayıncı:

Bingol University

Ana Başlıklar:

Sağlık Kurumları Yönetimi

Dergi:

Türk Doğa ve Fen Dergisi Vol.12 Issue 2, pp.1-7

Belge Tipi:

Makale

Yayın Tarihi:

6/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001292404

pISSN:

2149-6366