Green Synthesis, Characterization and Determination of Biological Activity of Sunflower Honey Based-Silver Nanoparticles

Merve Keskin

Makale detayları

Green Synthesis, Characterization and Determination of Biological Activity of Sunflower Honey Based-Silver Nanoparticles

Yazarlar:

Merve Keskin

Yayıncı:

Bursa Uludağ University

Ana Başlıklar:

Geleneksel | Tamamlayıcı ve Bütünleştirici Tıp (Diğer) | Kimya Mühendisliği (Diğer)

Dergi:

Uludağ Arıcılık Dergisi Vol.24 Issue 2, pp.311-324

Belge Tipi:

Makale

Yayın Tarihi:

11/2024

Belge Dili:

Türkçe

Document ID (Org No.):

2001331460

pISSN:

2687-5594

Anahtar kelimeler:

Özet:

 Nanoparticles such as gold, silver, zinc, which are the building blocks of nanotechnology, which have a wide range of applications in medicine, drug release systems, pharmacy, agriculture, can be synthesized in an environmentally friendly, economical and biocompatible way using green synthesis technique. In the green synthesis of silver nanoparticles, plants or plant-based products are widely used due to the bioactive components they contain. Honey is one of the important natural products that can be used in the synthesis of silver nanoparticles with its phenolic components and sugars. In this study, the potential of sunflower honey, which is weaker than chestnut and oak honey in terms of bioactive components, for the synthesis of silver nanoparticles was determined. The synthesized sunflower honey-based silver nanoparticles SH-AgNPs were characterized and then their antioxidant activity and inhibition of myeloperoxidase and collagenase enzymes, which play an important role in wound healing, were determined. It was determined that the synthesized nanoparticles gave maximum absorbance at 440 nm and particle sizes ranged between 33 nm and 38 nm. The DPPH radical scavenging activities and ferric reducing capacity FRAP of the synthesized nanoparticles were determined as 811.42 and 861.24, respectively, and the inhibition properties of myleoperoxidase and collagenase enzymes were determined as 631.45 and 371.14, respectively. The findings obtained show that sunflower honey has the potential for use in the field of nanotechnology.

 Nanoparticles such as gold, silver, zinc, which are the building blocks of nanotechnology, which have a wide range of applications in medicine, drug release systems, pharmacy, agriculture, can be synthesized in an environmentally friendly, economical and biocompatible way using green synthesis technique. In the green synthesis of silver nanoparticles, plants or plant-based products are widely used due to the bioactive components they contain. Honey is one of the important natural products that can be used in the synthesis of silver nanoparticles with its phenolic components and sugars. In this study, the potential of sunflower honey, which is weaker than chestnut and oak honey in terms of bioactive components, for the synthesis of silver nanoparticles was determined. The synthesized sunflower honey-based silver nanoparticles SH-AgNPs were characterized and then their antioxidant activity and inhibition of myeloperoxidase and collagenase enzymes, which play an important role in wound healing, were determined. It was determined that the synthesized nanoparticles gave maximum absorbance at 440 nm and particle sizes ranged between 33 nm and 38 nm. The DPPH radical scavenging activities and ferric reducing capacity FRAP of the synthesized nanoparticles were determined as 811.42 and 861.24, respectively, and the inhibition properties of myleoperoxidase and collagenase enzymes were determined as 631.45 and 371.14, respectively. The findings obtained show that sunflower honey has the potential for use in the field of nanotechnology.

 Nanoparticles such as gold, silver, zinc, which are the building blocks of nanotechnology, which have a wide range of applications in medicine, drug release systems, pharmacy, agriculture, can be synthesized in an environmentally friendly, economical and biocompatible way using green synthesis technique. In the green synthesis of silver nanoparticles, plants or plant-based products are widely used due to the bioactive components they contain. Honey is one of the important natural products that can be used in the synthesis of silver nanoparticles with its phenolic components and sugars. In this study, the potential of sunflower honey, which is weaker than chestnut and oak honey in terms of bioactive components, for the synthesis of silver nanoparticles was determined. The synthesized sunflower honey-based silver nanoparticles SH-AgNPs were characterized and then their antioxidant activity and inhibition of myeloperoxidase and collagenase enzymes, which play an important role in wound healing, were determined. It was determined that the synthesized nanoparticles gave maximum absorbance at 440 nm and particle sizes ranged between 33 nm and 38 nm. The DPPH radical scavenging activities and ferric reducing capacity FRAP of the synthesized nanoparticles were determined as 811.42 and 861.24, respectively, and the inhibition properties of myleoperoxidase and collagenase enzymes were determined as 631.45 and 371.14, respectively. The findings obtained show that sunflower honey has the potential for use in the field of nanotechnology.

 Tıp, ilaç salınım sistemleri, eczacılık, tarım gibi geniş bir yelpazede uygulama alanı bulan nanoteknolojinin yapı taşları olan altın, gümüş, çinko gibi nanopartiküller yeşil sentez tekniği kullanılarak çevre dostu, ekonomik ve biyouyumlu olarak sentezlenebilmektedir. Gümüş nanopartiküllerin yeşil sentezinde içermiş oldukları biyoaktif bileşenler nedeniyle bitkiler veya bitki temelli ürünler yaygın olarak kullanılmaktadır. Bal içermiş olduğu fenolik bileşenler ve şekerler ile gümüş nanopartiküllerin sentezinde kullanılabilecek önemli doğal ürünlerden biridir. Yapılan bu çalışmada, biyoaktif bileşen yönünden kestane ve meşe balına göre daha zayıf olan ayçiçeği balının gümüş nanopartiküllerin sentezinde kullanım potansiyeli tespit edilmiştir. Sentezlenen ayçiçeği balı temelli gümüş nanopartiküller SH-AgNPs karakterize edilmiş ve daha sonra antioksidan aktiviteleri ile yara iyileşmede önemli rolü olan myeloperoksidaz ve kollegenaz enzimleri inhibe etme özellikleri tespit edilmiştir. Sentezlenen nanopartiküllerin 440 nm de maksimum absorbans verdiği, partikül boyutlarnın 33 nm ile 38 nm arasında değiştiği tespit edilmiştir. Sentezlenen nanopartiküllerin DPPHradikal süpürme aktiviteleri ve FRAP demir indirgeme kapasiteleri sırasıyla  811,42 and  861,24; myleoperksidaz ile kollegenaz enzimlerini inhibe etme özellikleri sırasıyla  631,45 and  371,14 olarak tespit edildi. Elde edilen bulgular ayçiçeği balının nanoteknoloji alanında kullanım potansiyeli olduğunu göstermektedir.

Makale detayları

Green Synthesis, Characterization and Determination of Biological Activity of Sunflower Honey Based-Silver Nanoparticles

Yazarlar:

Merve Keskin

Yayıncı:

Bursa Uludağ University

Ana Başlıklar:

Geleneksel | Tamamlayıcı ve Bütünleştirici Tıp (Diğer) | Kimya Mühendisliği (Diğer)

Dergi:

Uludağ Arıcılık Dergisi Vol.24 Issue 2, pp.311-324

Belge Tipi:

Makale

Yayın Tarihi:

11/2024

Belge Dili:

Türkçe

Document ID (Org No.):

2001331460

pISSN:

2687-5594

Biological synthesis

Silver nanoparticles

Nanotechnology

Antioxidant activity

Enzyme inhibitionBiyolojik sentez

Gümüş nanopartikül

Nanoteknoloji

Antioksidan aktivite

Enzim inhibisyonu

Sayı

Makale detayları

Yazarlar: Merve Keskin

Yayıncı: Bursa Uludağ University

Ana Başlıklar: Geleneksel | Tamamlayıcı ve Bütünleştirici Tıp (Diğer) | Kimya Mühendisliği (Diğer)

Dergi: Uludağ Arıcılık Dergisi Vol.24 Issue 2, pp.311-324

Belge Tipi: Makale

Yayın Tarihi: 11/2024

Belge Dili: Türkçe

Document ID (Org No.): 2001331460

pISSN: 2687-5594

Sayı

Yazarlar:

Merve Keskin

Yayıncı:

Bursa Uludağ University

Ana Başlıklar:

Geleneksel | Tamamlayıcı ve Bütünleştirici Tıp (Diğer) | Kimya Mühendisliği (Diğer)

Dergi:

Uludağ Arıcılık Dergisi Vol.24 Issue 2, pp.311-324

Belge Tipi:

Makale

Yayın Tarihi:

11/2024

Belge Dili:

Türkçe

Document ID (Org No.):

2001331460

pISSN:

2687-5594