Dosimetric Comparison of Inverse Planning Simulated Annealing and Manual Optimization for Intracavitary Cervix Brachytherapy

Osman Vefa Gül; Hamit Başaran; Mursel Duzova; Gökçen İnan

Makale detayları

Dosimetric Comparison of Inverse Planning Simulated Annealing and Manual Optimization for Intracavitary Cervix Brachytherapy

Yazarlar:

Osman Vefa Gül | Hamit Başaran | Mursel Duzova | Gökçen İnan

Yayıncı:

Selcuk University

Ana Başlıklar:

Klinik Onkoloji

Dergi:

Genel Tıp Dergisi Vol.34 Issue 1, pp.109-113

Belge Tipi:

Makale

Yayın Tarihi:

2/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001312233

pISSN:

2602-3741

Anahtar kelimeler:

Özet:

 BackgroundAims: Different optimization methods in brachytherapy treatment planning is used. The aim of this study is to evaluate dosimetric differences between manual optimization MO and inverse planning simulated annealing IPSA planning techniques commonly used in brachytherapy of cervical cancer. Methods: Fifteen cervical cancer patients were included in this study. Nucletron standard tandem-ovoid TO applicators were used for treatment. High-risk clinical tumor volume HR-CTV, bladder, rectum, and sigmoid contouring were performed according to GEC-ESTRO recommendations. Two plans were created for each patient using IPSA and MO techniques. While a dose of 700 cGy was prescribed to the target volume during the planning phase, an effort was made to protect the organs at risk in the best way possible. IPSA and MO planning techniques were compared via dose volume histogram DVH. Results: There was no significant difference between HR-CTV and CI values for MO and IPSA techniques. There was a significant difference between IPSA and MO techniques for the 2cm3 volume of the rectum p 0.002. It was observed that the bladder was better protected by the IPSA technique. There was a 6.26 dose difference between IPSA and MO for the bladder. A significant difference was found between IPSA and MO techniques for the 2cm3 volume of the sigmoid p 0.002. The IPSA technique was superior to the MO technique in terms of time. Conclusions: The IPSA technique was superior to the MO technique in terms of protecting organs at risk OARs. IPSA provides a faster and higher quality plan in cervical brachytherapy.

 BackgroundAims: Different optimization methods in brachytherapy treatment planning is used. The aim of this study is to evaluate dosimetric differences between manual optimization MO and inverse planning simulated annealing IPSA planning techniques commonly used in brachytherapy of cervical cancer. Methods: Fifteen cervical cancer patients were included in this study. Nucletron standard tandem-ovoid TO applicators were used for treatment. High-risk clinical tumor volume HR-CTV, bladder, rectum, and sigmoid contouring were performed according to GEC-ESTRO recommendations. Two plans were created for each patient using IPSA and MO techniques. While a dose of 700 cGy was prescribed to the target volume during the planning phase, an effort was made to protect the organs at risk in the best way possible. IPSA and MO planning techniques were compared via dose volume histogram DVH. Results: There was no significant difference between HR-CTV and CI values for MO and IPSA techniques. There was a significant difference between IPSA and MO techniques for the 2cm3 volume of the rectum p 0.002. It was observed that the bladder was better protected by the IPSA technique. There was a 6.26 dose difference between IPSA and MO for the bladder. A significant difference was found between IPSA and MO techniques for the 2cm3 volume of the sigmoid p 0.002. The IPSA technique was superior to the MO technique in terms of time. Conclusions: The IPSA technique was superior to the MO technique in terms of protecting organs at risk OARs. IPSA provides a faster and higher quality plan in cervical brachytherapy.

 BackgroundAims: Different optimization methods in brachytherapy treatment planning is used. The aim of this study is to evaluate dosimetric differences between manual optimization MO and inverse planning simulated annealing IPSA planning techniques commonly used in brachytherapy of cervical cancer. Methods: Fifteen cervical cancer patients were included in this study. Nucletron standard tandem-ovoid TO applicators were used for treatment. High-risk clinical tumor volume HR-CTV, bladder, rectum, and sigmoid contouring were performed according to GEC-ESTRO recommendations. Two plans were created for each patient using IPSA and MO techniques. While a dose of 700 cGy was prescribed to the target volume during the planning phase, an effort was made to protect the organs at risk in the best way possible. IPSA and MO planning techniques were compared via dose volume histogram DVH. Results: There was no significant difference between HR-CTV and CI values for MO and IPSA techniques. There was a significant difference between IPSA and MO techniques for the 2cm3 volume of the rectum p 0.002. It was observed that the bladder was better protected by the IPSA technique. There was a 6.26 dose difference between IPSA and MO for the bladder. A significant difference was found between IPSA and MO techniques for the 2cm3 volume of the sigmoid p 0.002. The IPSA technique was superior to the MO technique in terms of time. Conclusions: The IPSA technique was superior to the MO technique in terms of protecting organs at risk OARs. IPSA provides a faster and higher quality plan in cervical brachytherapy.

 ArkaplanHedefler: Brakiterapi tedavi planlamasında farklı optimizasyon yöntemleri kullanılmaktadır. Bu çalışmanın amacı, serviks kanserinin brakiterapisinde yaygın olarak kullanılan manuel optimizasyon MO ve ters planlama simüle edilmiş tavlama IPSA planlama teknikleri arasındaki dozimetrik farklılıkları değerlendirmektir. Yöntemler: Bu çalışmaya on beş serviks kanseri hasta dahil edildi. Tedavide Nucletron standart tandem-ovoid TO aplikatörler kullanıldı. Yüksek riskli klinik tümör hacmi HR-CTV, mesane, rektum ve sigmoid şekillendirme GEC-ESTRO tavsiyelerine göre yapıldı. IPSA ve MO teknikleri kullanılarak her hasta için iki plan oluşturuldu. Planlama aşamasında hedef hacme 700 cGy doz reçete edilirken, risk altındaki organların en iyi şekilde korunmasına çalışıldı. IPSA ve MO planlama teknikleri doz hacim histogramı DVH aracılığıyla karşılaştırıldı. Bulgular: MO ve IPSA teknikleri için HR-CTV ve CI değerleri arasında anlamlı fark yoktu. Rektumun 2cm3 hacmi açısından IPSA ve MO teknikleri arasında anlamlı fark vardı p 0.002. IPSA tekniği ile mesanenin daha iyi korunduğu görüldü. Mesane için IPSA ve MO arasında 6,26 doz farkı vardı. Sigmoidin 2cm3 hacmi açısından IPSA ve MO teknikleri arasında anlamlı fark bulundu p 0.002. IPSA tekniği zaman açısından MO tekniğinden üstündü. Sonuç: IPSA tekniği risk altındaki organların OARs korunması açısından MO tekniğinden üstündü. IPSA, serviks brakiterapisinde daha hızlı ve kaliteli bir plan sağlar.

Makale detayları

Dosimetric Comparison of Inverse Planning Simulated Annealing and Manual Optimization for Intracavitary Cervix Brachytherapy

Yazarlar:

Osman Vefa Gül | Hamit Başaran | Mursel Duzova | Gökçen İnan

Yayıncı:

Selcuk University

Ana Başlıklar:

Klinik Onkoloji

Dergi:

Genel Tıp Dergisi Vol.34 Issue 1, pp.109-113

Belge Tipi:

Makale

Yayın Tarihi:

2/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001312233

pISSN:

2602-3741

Brachytherapy

Cervix cancer

IPSABrakiterapi

Serviks kanseri

IPSA

Sayı

Makale detayları

Dosimetric Comparison of Inverse Planning Simulated Annealing and Manual Optimization for Intracavitary Cervix Brachytherapy

Yazarlar: Osman Vefa Gül | Hamit Başaran | Mursel Duzova | Gökçen İnan

Yayıncı: Selcuk University

Ana Başlıklar: Klinik Onkoloji

Dergi: Genel Tıp Dergisi Vol.34 Issue 1, pp.109-113

Belge Tipi: Makale

Yayın Tarihi: 2/2024

Belge Dili: İngilizce

Document ID (Org No.): 2001312233

pISSN: 2602-3741

Brachytherapy

Cervix cancer

IPSABrakiterapi

Serviks kanseri

IPSA

Sayı

Yazarlar:

Osman Vefa Gül | Hamit Başaran | Mursel Duzova | Gökçen İnan

Yayıncı:

Selcuk University

Ana Başlıklar:

Klinik Onkoloji

Dergi:

Genel Tıp Dergisi Vol.34 Issue 1, pp.109-113

Belge Tipi:

Makale

Yayın Tarihi:

2/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001312233

pISSN:

2602-3741