Efficacy and safety of topical dapsone versus topical tetracycline in mild to moderate acne vulgaris: a retrospective analysis

Sabir Hasanbeyzade

Makale detayları

Efficacy and safety of topical dapsone versus topical tetracycline in mild to moderate acne vulgaris: a retrospective analysis

Yazarlar:

Sabir Hasanbeyzade

Yayıncı:

Kafkas University

Ana Başlıklar:

Dermatoloji

Dergi:

Kafkas Tıp Bilimleri Dergisi Vol.15 Issue 1, pp.1-5

Belge Tipi:

Makale

Yayın Tarihi:

4/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001347642

pISSN:

2146-2631

Anahtar kelimeler:

Özet:

 Objective: In this study,we compared the efficacy and side effects of topical 7.5 dapsone and 3 tetracycline in patients with mild and moderate acne. Methods: The study was approved by the hospitals clinical Ethics Committee.A total of 100 subjects aged 12-40 years were enrolled in the study and each group contained 50 subjects who applied to the dermatology clinic with the complaint of acne on 01.09.22-30.11.22,were diagnosed with mild and moderate acne,and were treated with topical 7.5 dapsone or 3 tetracycline for at least 12 weeks. Results: A statistically significant difference was found between the 2 groups in terms of acne scores and lesion numbers at the end of the treatment p0.006 for acne score,0.002 for open comedones and 0.001 for other types of lesions.There was also a significant difference between the 2 groups in terms of patients with an acne score of 0 or 1 after 12 weeks of treatment p0.007.At the end of the first month,there was a difference between the 2 groups in terms of erythema,dryness and burningstinging side effects respectively p0.009, 0.009 and 0.001. Conclusion: Our results suggest that topical 7.5 dapsone is effective in the treatment of mild to moderate acne and is safe in terms of side effects compared to topical 3 tetracycline.

 Objective: In this study,we compared the efficacy and side effects of topical 7.5 dapsone and 3 tetracycline in patients with mild and moderate acne. Methods: The study was approved by the hospitals clinical Ethics Committee.A total of 100 subjects aged 12-40 years were enrolled in the study and each group contained 50 subjects who applied to the dermatology clinic with the complaint of acne on 01.09.22-30.11.22,were diagnosed with mild and moderate acne,and were treated with topical 7.5 dapsone or 3 tetracycline for at least 12 weeks. Results: A statistically significant difference was found between the 2 groups in terms of acne scores and lesion numbers at the end of the treatment p0.006 for acne score,0.002 for open comedones and 0.001 for other types of lesions.There was also a significant difference between the 2 groups in terms of patients with an acne score of 0 or 1 after 12 weeks of treatment p0.007.At the end of the first month,there was a difference between the 2 groups in terms of erythema,dryness and burningstinging side effects respectively p0.009, 0.009 and 0.001. Conclusion: Our results suggest that topical 7.5 dapsone is effective in the treatment of mild to moderate acne and is safe in terms of side effects compared to topical 3 tetracycline.

 Objective: In this study,we compared the efficacy and side effects of topical 7.5 dapsone and 3 tetracycline in patients with mild and moderate acne. Methods: The study was approved by the hospitals clinical Ethics Committee.A total of 100 subjects aged 12-40 years were enrolled in the study and each group contained 50 subjects who applied to the dermatology clinic with the complaint of acne on 01.09.22-30.11.22,were diagnosed with mild and moderate acne,and were treated with topical 7.5 dapsone or 3 tetracycline for at least 12 weeks. Results: A statistically significant difference was found between the 2 groups in terms of acne scores and lesion numbers at the end of the treatment p0.006 for acne score,0.002 for open comedones and 0.001 for other types of lesions.There was also a significant difference between the 2 groups in terms of patients with an acne score of 0 or 1 after 12 weeks of treatment p0.007.At the end of the first month,there was a difference between the 2 groups in terms of erythema,dryness and burningstinging side effects respectively p0.009, 0.009 and 0.001. Conclusion: Our results suggest that topical 7.5 dapsone is effective in the treatment of mild to moderate acne and is safe in terms of side effects compared to topical 3 tetracycline.

 Objective: In this study,we compared the efficacy and side effects of topical 7.5 dapsone and 3 tetracycline in patients with mild and moderate acne. Methods: The study was approved by the hospitals clinical Ethics Committee.A total of 100 subjects aged 12-40 years were enrolled in the study and each group contained 50 subjects who applied to the dermatology clinic with the complaint of acne on 01.09.22-30.11.22,were diagnosed with mild and moderate acne,and were treated with topical 7.5 dapsone or 3 tetracycline for at least 12 weeks. Results: A statistically significant difference was found between the 2 groups in terms of acne scores and lesion numbers at the end of the treatment p0.006 for acne score,0.002 for open comedones and 0.001 for other types of lesions.There was also a significant difference between the 2 groups in terms of patients with an acne score of 0 or 1 after 12 weeks of treatment p0.007.At the end of the first month,there was a difference between the 2 groups in terms of erythema,dryness and burningstinging side effects respectively p0.009, 0.009 and 0.001. Conclusion: Our results suggest that topical 7.5 dapsone is effective in the treatment of mild to moderate acne and is safe in terms of side effects compared to topical 3 tetracycline.

Makale detayları

Efficacy and safety of topical dapsone versus topical tetracycline in mild to moderate acne vulgaris: a retrospective analysis

Yazarlar:

Sabir Hasanbeyzade

Yayıncı:

Kafkas University

Ana Başlıklar:

Dermatoloji

Dergi:

Kafkas Tıp Bilimleri Dergisi Vol.15 Issue 1, pp.1-5

Belge Tipi:

Makale

Yayın Tarihi:

4/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001347642

pISSN:

2146-2631

topical dapsone

acne and dapsone

tetracycline and dapsone

topical tetracycline

Sayı

Makale detayları

Efficacy and safety of topical dapsone versus topical tetracycline in mild to moderate acne vulgaris: a retrospective analysis

Yazarlar: Sabir Hasanbeyzade

Yayıncı: Kafkas University

Ana Başlıklar: Dermatoloji

Dergi: Kafkas Tıp Bilimleri Dergisi Vol.15 Issue 1, pp.1-5

Belge Tipi: Makale

Yayın Tarihi: 4/2025

Belge Dili: İngilizce

Document ID (Org No.): 2001347642

pISSN: 2146-2631

topical dapsone

acne and dapsone

tetracycline and dapsone

topical tetracycline

Sayı

Yazarlar:

Sabir Hasanbeyzade

Yayıncı:

Kafkas University

Ana Başlıklar:

Dermatoloji

Dergi:

Kafkas Tıp Bilimleri Dergisi Vol.15 Issue 1, pp.1-5

Belge Tipi:

Makale

Yayın Tarihi:

4/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001347642

pISSN:

2146-2631