Blood Leukocyte Ratios: Equivocal Parameters for Allergic Diseases

N.A.

Makale detayları

Blood Leukocyte Ratios: Equivocal Parameters for Allergic Diseases

Yazarlar:

N.A.

Yayıncı:

Ankara University

Ana Başlıklar:

Allergy

Dergi:

Ankara Üniversitesi Tıp Fakültesi Mecmuası Vol.78 Issue 1, pp.13-19

Belge Tipi:

Makale

Yayın Tarihi:

3/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001349818

pISSN:

0365-8104

Anahtar kelimeler:

Özet:

 Objectives: Leukocytes play crucial roles in allergic and immunologic diseases. We compared neutrophil-lymphocyte ratio NLR, basophillymphocyte ratio BLR, eosinophil-neutrophil ratio ENR, and eosinophil-lymphocyte ratio ELR in 100 drug-induced urticaria-angioedema, 100 drugvenom-triggered anaphylaxis cases, and 100 healthy controls to assess their association with the severity of the allergic reaction. Materials and Methods: Retrospective analysis of blood leukocyte counts and ratios was performed. Results: Median NLR was 1.975 in patients 2.09 in urticaria-angioedema, 1.905 in anaphylaxis and 1.815 in controls. NLR was significantly higher in patients p0.038 and notably elevated in urticaria-angioedema p0.008. No significant differences in NLR were found between the urticaria-angioedema and anaphylaxis groups p0.09 or between the anaphylaxis and control groups p0.342. Other leukocyte ratios showed no significant changes between patient and control groups p0.05. Conclusion: NLR may indicate allergic responses but doesnt have predictive value for reaction type or severity.

 Objectives: Leukocytes play crucial roles in allergic and immunologic diseases. We compared neutrophil-lymphocyte ratio NLR, basophillymphocyte ratio BLR, eosinophil-neutrophil ratio ENR, and eosinophil-lymphocyte ratio ELR in 100 drug-induced urticaria-angioedema, 100 drugvenom-triggered anaphylaxis cases, and 100 healthy controls to assess their association with the severity of the allergic reaction. Materials and Methods: Retrospective analysis of blood leukocyte counts and ratios was performed. Results: Median NLR was 1.975 in patients 2.09 in urticaria-angioedema, 1.905 in anaphylaxis and 1.815 in controls. NLR was significantly higher in patients p0.038 and notably elevated in urticaria-angioedema p0.008. No significant differences in NLR were found between the urticaria-angioedema and anaphylaxis groups p0.09 or between the anaphylaxis and control groups p0.342. Other leukocyte ratios showed no significant changes between patient and control groups p0.05. Conclusion: NLR may indicate allergic responses but doesnt have predictive value for reaction type or severity.

 Objectives: Leukocytes play crucial roles in allergic and immunologic diseases. We compared neutrophil-lymphocyte ratio NLR, basophillymphocyte ratio BLR, eosinophil-neutrophil ratio ENR, and eosinophil-lymphocyte ratio ELR in 100 drug-induced urticaria-angioedema, 100 drugvenom-triggered anaphylaxis cases, and 100 healthy controls to assess their association with the severity of the allergic reaction. Materials and Methods: Retrospective analysis of blood leukocyte counts and ratios was performed. Results: Median NLR was 1.975 in patients 2.09 in urticaria-angioedema, 1.905 in anaphylaxis and 1.815 in controls. NLR was significantly higher in patients p0.038 and notably elevated in urticaria-angioedema p0.008. No significant differences in NLR were found between the urticaria-angioedema and anaphylaxis groups p0.09 or between the anaphylaxis and control groups p0.342. Other leukocyte ratios showed no significant changes between patient and control groups p0.05. Conclusion: NLR may indicate allergic responses but doesnt have predictive value for reaction type or severity.

 Amaç: Lökositler, alerjik ve immünolojik hastalıklarda önemli roller oynar. Nötrofil-lenfosit oranı NLR, bazofil-lenfosit oranı BLR, eozinofilnötrofil oranı ENR ve eozinofil-lenfosit oranı ELR ölçümlerini, 100 ilaçla tetiklenen ürtiker-anjioödem, 100 ilaçvenom ile tetiklenen anafilaksi olgusu ve 100 sağlıklı kontrol olgusunda karşılaştırarak bu oranların alerjik reaksiyonun şiddeti ile ilişkilerini değerlendirmeyi amaçladık. Gereç ve Yöntem: Kan lökosit sayıları ve oranlarının retrospektif analizi gerçekleştirildi. Bulgular: Hastalarda median NLR değeri 1,975 idi ürtiker-anjioödem grubunda 2,09, anafilaksi grubunda 1,905, kontrol grubunda ise 1,815 olarak belirlendi. NLR, hasta grubunda anlamlı derecede yüksekti p0,038 ve özellikle ürtiker-anjioödem grubunda belirgin şekilde yükselmişti p0,008. Ürtiker-anjioödem ve anafilaksi grupları arasında p0,09 ve anafilaksi ile kontrol grupları arasında p0.342 NLR değerlerinde anlamlı fark bulunmadı. Diğer lökosit oranları, hasta ve kontrol grupları arasında anlamlı değişiklikler göstermedi p0,05. Sonuç: NLR, alerjik reaksiyonlar için bir belirteç olabilir, ancak reaksiyon türü veya şiddeti için öngörü değeri bulunmamaktadır.

Makale detayları

Blood Leukocyte Ratios: Equivocal Parameters for Allergic Diseases

Yazarlar:

N.A.

Yayıncı:

Ankara University

Ana Başlıklar:

Allergy

Dergi:

Ankara Üniversitesi Tıp Fakültesi Mecmuası Vol.78 Issue 1, pp.13-19

Belge Tipi:

Makale

Yayın Tarihi:

3/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001349818

pISSN:

0365-8104

Anaphylaxis

angioedema

inflammation

leukocyte

urticariaAnafilaksi

anjioödem

enflamasyon

lökosit

ürtiker

Sayı

Makale detayları

Yazarlar: N.A.

Yayıncı: Ankara University

Ana Başlıklar: Allergy

Dergi: Ankara Üniversitesi Tıp Fakültesi Mecmuası Vol.78 Issue 1, pp.13-19

Belge Tipi: Makale

Yayın Tarihi: 3/2025

Belge Dili: İngilizce

Document ID (Org No.): 2001349818

pISSN: 0365-8104

Sayı

Yazarlar:

N.A.

Yayıncı:

Ankara University

Ana Başlıklar:

Allergy

Dergi:

Ankara Üniversitesi Tıp Fakültesi Mecmuası Vol.78 Issue 1, pp.13-19

Belge Tipi:

Makale

Yayın Tarihi:

3/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001349818

pISSN:

0365-8104