HDL-C as a new therapeutic target in the treatment of dyslipidemia

Sahin I

Makale detayları

HDL-C as a new therapeutic target in the treatment of dyslipidemia

Yazarlar:

Sahin I

Yayıncı:

Inonu University

Dergi:

Medicine Science 2012 Vol.1 Issue 2, pp.141-149

Belge Tipi:

Makale

Yayın Tarihi:

5/2012

Belge Dili:

Türkçe

Document ID (Org No.):

2000828858

Sıklık:

Üç Aylık

eISSN:

2147-0634

pISSN:

2147-0634

Anahtar kelimeler:

Özet:

 

Clinical and epidemiological studies have suggested that low plasma levels of high-density lipoproteins cholesterol (HDL-C) are independently associated with an increased risk of cardio-vascular diseases (CVD). Accumulated data from epidemiologic, animal models and clinical studies support the view that raising HDL may be an effective new target to decrease cardio-vascular risks. New insights in the understanding of the physiology, mechanisms and pathways by which HDL may reduce atherosclerosis allow new promising agents for increasing plasma HDL-C. In this regards, apo-AI analogs, acute HDL-C infusions therapies and new cholesteryl ester transfer protein CETP inhibitors have opened new expectations in the treatment of CVD.

 

Clinical and epidemiological studies have suggested that low plasma levels of high-density lipoproteins cholesterol (HDL-C) are independently associated with an increased risk of cardio-vascular diseases (CVD). Accumulated data from epidemiologic, animal models and clinical studies support the view that raising HDL may be an effective new target to decrease cardio-vascular risks. New insights in the understanding of the physiology, mechanisms and pathways by which HDL may reduce atherosclerosis allow new promising agents for increasing plasma HDL-C. In this regards, apo-AI analogs, acute HDL-C infusions therapies and new cholesteryl ester transfer protein CETP inhibitors have opened new expectations in the treatment of CVD.

Makale detayları

HDL-C as a new therapeutic target in the treatment of dyslipidemia

Yazarlar:

Sahin I

Yayıncı:

Inonu University

Dergi:

Medicine Science 2012 Vol.1 Issue 2, pp.141-149

Belge Tipi:

Makale

Yayın Tarihi:

5/2012

Belge Dili:

Türkçe

Document ID (Org No.):

2000828858

Sıklık:

Üç Aylık

eISSN:

2147-0634

pISSN:

2147-0634

HDL

cardiovascular risks

treatment

Sayı

Makale detayları

HDL-C as a new therapeutic target in the treatment of dyslipidemia

Yazarlar: Sahin I

Yayıncı: Inonu University

Dergi: Medicine Science 2012 Vol.1 Issue 2, pp.141-149

Belge Tipi: Makale

Yayın Tarihi: 5/2012

Belge Dili: Türkçe

Document ID (Org No.): 2000828858

Sıklık: Üç Aylık

eISSN: 2147-0634

pISSN: 2147-0634

HDL

cardiovascular risks

treatment

Sayı

Yazarlar:

Sahin I

Yayıncı:

Inonu University

Dergi:

Medicine Science 2012 Vol.1 Issue 2, pp.141-149

Belge Tipi:

Makale

Yayın Tarihi:

5/2012

Belge Dili:

Türkçe

Document ID (Org No.):

2000828858

Sıklık:

Üç Aylık

eISSN:

2147-0634

pISSN:

2147-0634