The effect of transcatheter aortic valve implantation on mean platelet volume

Mehmet Burak ÖZEN; Hüseyin AYHAN; Haci Ahmet KASAPKARA; Telat KELEŞ; Tahir DURMAZ; Kemal Eşref ERDOĞAN; Bilge Duran KARADUMAN; Serdal BAŞTUĞ; Cenk SARI; Abdullah Nabi ASLAN; Engin BOZKURT

Makale detayları

The effect of transcatheter aortic valve implantation on mean platelet volume

Yazarlar:

Mehmet Burak ÖZEN | Hüseyin AYHAN | Haci Ahmet KASAPKARA | Telat KELEŞ | Tahir DURMAZ | Kemal Eşref ERDOĞAN | Bilge Duran KARADUMAN | Serdal BAŞTUĞ | Cenk SARI | Abdullah Nabi ASLAN | Engin BOZKURT

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2017 Vol.47 Issue 2, pp.385-390

Belge Tipi:

Makale

Yayın Tarihi:

3/2017

Belge Dili:

Türkçe

Document ID (Org No.):

2000751384

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144

Özet:

 

Background/aim: Transcatheter aortic valve implantation (TAVI) is an innovative approach to the treatment of aortic stenosis (AS)  as an alternative to surgery in high-risk patients. Mean platelet volume (MPV) is considered an indicator of endothelial dysfunction,  platelet function, and activation. In this study, we aimed to investigate MPV changes in patients undergoing TAVI.  Materials and methods: This study included 100 patients diagnosed with symptomatic severe AS and treated with TAVI between July  2011 and August 2013. Hematological parameters of the patients were examined prior to the procedure and 24 h, 1 month, and 6 months  after TAVI.  Results: A statistically significant change in patients' MPV was detected after TAVI compared to the baseline situation (P: 0.001). While  no statistically significant change was observed on the first day after TAVI, at discharge, compared to the baseline situation, a statistically  significant decrease was seen 1 month and 6 months after discharge.  Conclusion: We have demonstrated a decrease in MPV after surgery compared to the value before surgery. We have sought to propound  the change in MPV as an indication of endothelial function after TAVI.

Makale detayları

The effect of transcatheter aortic valve implantation on mean platelet volume

Yazarlar: Mehmet Burak ÖZEN | Hüseyin AYHAN | Haci Ahmet KASAPKARA | Telat KELEŞ | Tahir DURMAZ | Kemal Eşref ERDOĞAN | Bilge Duran KARADUMAN | Serdal BAŞTUĞ | Cenk SARI | Abdullah Nabi ASLAN | Engin BOZKURT

Yayıncı: TUBITAK

Dergi: Turkish Journal of Medical Sciences 2017 Vol.47 Issue 2, pp.385-390

Belge Tipi: Makale

Yayın Tarihi: 3/2017

Belge Dili: Türkçe

Document ID (Org No.): 2000751384

Sıklık: İki Aylık

eISSN: 1303-6165

pISSN: 1300-0144

Sayı

Yazarlar:

Mehmet Burak ÖZEN | Hüseyin AYHAN | Haci Ahmet KASAPKARA | Telat KELEŞ | Tahir DURMAZ | Kemal Eşref ERDOĞAN | Bilge Duran KARADUMAN | Serdal BAŞTUĞ | Cenk SARI | Abdullah Nabi ASLAN | Engin BOZKURT

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2017 Vol.47 Issue 2, pp.385-390

Belge Tipi:

Makale

Yayın Tarihi:

3/2017

Belge Dili:

Türkçe

Document ID (Org No.):

2000751384

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144