The prevalence of tuberculin skin test positivity and the effect of BCG vaccinations on tuberculin induration size in the eastern Mediterranean region of Turkey

Ferda KAZANCI; Ekrem GÜLER; Canan EREN DAĞLI; Mesut GARİPARDIÇ; Mehmet DAVUTOĞLU; Esen İSPİROĞLU; Hasan Çetin EKERBİÇER; Hamza KARABİBER

Makale detayları

The prevalence of tuberculin skin test positivity and the effect of BCG vaccinations on tuberculin induration size in the eastern Mediterranean region of Turkey

Yazarlar:

Ferda KAZANCI | Ekrem GÜLER | Canan EREN DAĞLI | Mesut GARİPARDIÇ | Mehmet DAVUTOĞLU | Esen İSPİROĞLU | Hasan Çetin EKERBİÇER | Hamza KARABİBER

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2011 Vol.41 Issue 4, pp.711-718

Belge Tipi:

Makale

Yayın Tarihi:

3/2011

Belge Dili:

Türkçe

Document ID (Org No.):

2000754661

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144

Anahtar kelimeler:

Özet:

 

To evaluate the prevalence of tuberculin skin test (TST) positivity in Kahramanmaraş and interpret the size of purified protein derivative (PPD) induration with respect to the number of Bacillus Calmette-Guerin (BCG) scars and other factors.  Materials and methods: A total of 2979 school children between the ages of 7 and 17 years were evaluated. On the basis of socioeconomic levels, 11 schools were selected and categorized into 3 subgroups: schools in the suburbs of the city (Group 1), schools in the city center (Group 2), and private schools (Group 3). Children were injected with 5 TU/0.1 mL of PPD and the sizes of induration were measured after 72 h. The number of BCG scars and the sizes of induration were recorded for each pupil.   Results: The TST was positive in 6.3% of the nonvaccinated students and in 7.5% of the vaccinated students (P > 0.05). The number of BCG vaccination scars was 0 in 174 children (5.8%), 1 in 1232 children (41.4%), 2 in 1516 children (50.9%), 3 in 54 children (1.8%), and 4 in 3 children (0.1%). The mean diameter of the size of the PPD induration for 0, 1, 2, 3, and 4 BCG vaccinations was 2.50 ± 4.05 mm, 5.60 ± 5.11 mm, 8.49 ± 5.09 mm, 8.46 ± 4.38 mm, and 7.66 ± 6.80 mm, respectively. The size of the induration was greatest in students vaccinated twice (P < 0.05). The TST positivity rate was highest in children 11-13 years of age (P < 0.05).  Conclusion: The BCG vaccination rate was higher in Kahramanmaraş, whereas the TST positivity rate was lower. The factors that affected the size of the PPD induration were the number of vaccination scars and the age of the subject.

 

To evaluate the prevalence of tuberculin skin test (TST) positivity in Kahramanmaraş and interpret the size of purified protein derivative (PPD) induration with respect to the number of Bacillus Calmette-Guerin (BCG) scars and other factors.  Materials and methods: A total of 2979 school children between the ages of 7 and 17 years were evaluated. On the basis of socioeconomic levels, 11 schools were selected and categorized into 3 subgroups: schools in the suburbs of the city (Group 1), schools in the city center (Group 2), and private schools (Group 3). Children were injected with 5 TU/0.1 mL of PPD and the sizes of induration were measured after 72 h. The number of BCG scars and the sizes of induration were recorded for each pupil.   Results: The TST was positive in 6.3% of the nonvaccinated students and in 7.5% of the vaccinated students (P > 0.05). The number of BCG vaccination scars was 0 in 174 children (5.8%), 1 in 1232 children (41.4%), 2 in 1516 children (50.9%), 3 in 54 children (1.8%), and 4 in 3 children (0.1%). The mean diameter of the size of the PPD induration for 0, 1, 2, 3, and 4 BCG vaccinations was 2.50 ± 4.05 mm, 5.60 ± 5.11 mm, 8.49 ± 5.09 mm, 8.46 ± 4.38 mm, and 7.66 ± 6.80 mm, respectively. The size of the induration was greatest in students vaccinated twice (P < 0.05). The TST positivity rate was highest in children 11-13 years of age (P < 0.05).  Conclusion: The BCG vaccination rate was higher in Kahramanmaraş, whereas the TST positivity rate was lower. The factors that affected the size of the PPD induration were the number of vaccination scars and the age of the subject.

Makale detayları

The prevalence of tuberculin skin test positivity and the effect of BCG vaccinations on tuberculin induration size in the eastern Mediterranean region of Turkey

Yazarlar:

Ferda KAZANCI | Ekrem GÜLER | Canan EREN DAĞLI | Mesut GARİPARDIÇ | Mehmet DAVUTOĞLU | Esen İSPİROĞLU | Hasan Çetin EKERBİÇER | Hamza KARABİBER

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2011 Vol.41 Issue 4, pp.711-718

Belge Tipi:

Makale

Yayın Tarihi:

3/2011

Belge Dili:

Türkçe

Document ID (Org No.):

2000754661

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144

Key words: Bacillus Calmette-Guerin vaccination

tuberculin skin test

tuberculosis

Sayı

Makale detayları

The prevalence of tuberculin skin test positivity and the effect of BCG vaccinations on tuberculin induration size in the eastern Mediterranean region of Turkey

Yazarlar: Ferda KAZANCI | Ekrem GÜLER | Canan EREN DAĞLI | Mesut GARİPARDIÇ | Mehmet DAVUTOĞLU | Esen İSPİROĞLU | Hasan Çetin EKERBİÇER | Hamza KARABİBER

Yayıncı: TUBITAK

Dergi: Turkish Journal of Medical Sciences 2011 Vol.41 Issue 4, pp.711-718

Belge Tipi: Makale

Yayın Tarihi: 3/2011

Belge Dili: Türkçe

Document ID (Org No.): 2000754661

Sıklık: İki Aylık

eISSN: 1303-6165

pISSN: 1300-0144

Key words: Bacillus Calmette-Guerin vaccination

tuberculin skin test

tuberculosis

Sayı

Yazarlar:

Ferda KAZANCI | Ekrem GÜLER | Canan EREN DAĞLI | Mesut GARİPARDIÇ | Mehmet DAVUTOĞLU | Esen İSPİROĞLU | Hasan Çetin EKERBİÇER | Hamza KARABİBER

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2011 Vol.41 Issue 4, pp.711-718

Belge Tipi:

Makale

Yayın Tarihi:

3/2011

Belge Dili:

Türkçe

Document ID (Org No.):

2000754661

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144