Study of binary complexes of nickel(II), copper(II), and vanadium(V) with acetazolamide in aqueous medium by voltammetry

İclal BULUT

Makale detayları

Study of binary complexes of nickel(II), copper(II), and vanadium(V) with acetazolamide in aqueous medium by voltammetry

Yazarlar:

İclal BULUT

Yayıncı:

TUBITAK

Ana Başlıklar:

Uygulamalı fizik

Dergi:

Turkish Journal of Chemistry 2009 Vol.33 Issue 4, pp.507-520

Belge Tipi:

Makale

Yayın Tarihi:

3/2009

Belge Dili:

İngilizce

Document ID (Org No.):

2000728260

Sıklık:

İki Aylık

eISSN:

1303-6130

pISSN:

1300-0527

Özet:

 

The voltammetric behaviour of acetazolamide, the systemic  carbonic anhydrase inhibitor, in the presence of some metal ions  (Cu(II), Ni(II), and V(V)) were investigated using square-wave and  cyclic voltammetry in physiological pH (pH 7.4).  Square-wave  voltammogram of acetazolamide in the absence of metal ions gave only 1  reduction peak at -1.65 V attributed to a catalytic hydrogen peak.  Three reversible peaks at -0.068, -0.262, and -0.434 V were observed  for the solutions containing both copper(II) ions and acetazolamide in  the SWV. The peak at -0.434 V was attributed to Cu(II)-acetazolamide  complex.  In the presence of acetazolamide, copper-acetazolamide  complex formation was proved by a reversible peak with 2 electron  transfers at -0.450 V. Complex formation of an adduct of  trioxovanadate(V) with acetazolamide onto dropping mercury electrode  was followed by a reduction peak at -0.480 V. Ni(II)-acetazolamide  complex was observed to reduce at the more positive potential (-0.830  V) than that of the hydrated Ni(II) ions (-1.200 V) implying that  acetazolamide is a catalyst for Ni(II) reduction at a mercury  electrode.  The UV-vis spectra of all the acetazolamide complexes were  also discussed.

 

The voltammetric behaviour of acetazolamide, the systemic  carbonic anhydrase inhibitor, in the presence of some metal ions  (Cu(II), Ni(II), and V(V)) were investigated using square-wave and  cyclic voltammetry in physiological pH (pH 7.4).  Square-wave  voltammogram of acetazolamide in the absence of metal ions gave only 1  reduction peak at -1.65 V attributed to a catalytic hydrogen peak.  Three reversible peaks at -0.068, -0.262, and -0.434 V were observed  for the solutions containing both copper(II) ions and acetazolamide in  the SWV. The peak at -0.434 V was attributed to Cu(II)-acetazolamide  complex.  In the presence of acetazolamide, copper-acetazolamide  complex formation was proved by a reversible peak with 2 electron  transfers at -0.450 V. Complex formation of an adduct of  trioxovanadate(V) with acetazolamide onto dropping mercury electrode  was followed by a reduction peak at -0.480 V. Ni(II)-acetazolamide  complex was observed to reduce at the more positive potential (-0.830  V) than that of the hydrated Ni(II) ions (-1.200 V) implying that  acetazolamide is a catalyst for Ni(II) reduction at a mercury  electrode.  The UV-vis spectra of all the acetazolamide complexes were  also discussed.

Makale detayları

Study of binary complexes of nickel(II), copper(II), and vanadium(V) with acetazolamide in aqueous medium by voltammetry

Yazarlar: İclal BULUT

Yayıncı: TUBITAK

Ana Başlıklar: Uygulamalı fizik

Dergi: Turkish Journal of Chemistry 2009 Vol.33 Issue 4, pp.507-520

Belge Tipi: Makale

Yayın Tarihi: 3/2009

Belge Dili: İngilizce

Document ID (Org No.): 2000728260

Sıklık: İki Aylık

eISSN: 1303-6130

pISSN: 1300-0527

Sayı

Yazarlar:

İclal BULUT

Yayıncı:

TUBITAK

Ana Başlıklar:

Uygulamalı fizik

Dergi:

Turkish Journal of Chemistry 2009 Vol.33 Issue 4, pp.507-520

Belge Tipi:

Makale

Yayın Tarihi:

3/2009

Belge Dili:

İngilizce

Document ID (Org No.):

2000728260

Sıklık:

İki Aylık

eISSN:

1303-6130

pISSN:

1300-0527