Comparison of sevoflurane insufflation and intravenous ketamine use in terms of failure rate in consecutive paediatrıc radiotherapy sessions: a cross-over study

Betül Güven Aytaç

Makale detayları

Comparison of sevoflurane insufflation and intravenous ketamine use in terms of failure rate in consecutive paediatrıc radiotherapy sessions: a cross-over study

Yazarlar:

Betül Güven Aytaç

Yayıncı:

MediHealth Academy Yayıncılık

Ana Başlıklar:

Anesteziyoloji

Dergi:

Journal of Medicine and Palliative Care Vol.4 Issue 5, pp.591-595

Belge Tipi:

Makale

Yayın Tarihi:

10/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001302599

pISSN:

2717-7505

Anahtar kelimeler:

Özet:

 Aim: Childhood cancers are often treated with radiotherapy. During radiation therapy, sedation is often required for immobilization, especially for young children and patients with mental disabilities. Our study aimed to compare the efficacy of sevoflurane insufflation and intravenous ketamine for sedation during pediatric radiotherapy. Materials and methods: This prospective, randomized, cross-over study was conducted between August and December 2020 on pediatric patients 1 month to 18 years requiring sedation or general anesthesia for radiotherapy. 352 repeated sessions were conducted in the study involving 18 patients who participated. Two groups were categorized by session: ketamine Group K or sevoflurane Group S. Results: The study included the evaluation of 352 sessions for 18 patients Although there was no significant difference in procedure times between Group S and Group K during the sessions p0.05, Group K showed a significantly longer discharge time, higher failure rate, and higher score sedation scale in comparison to Group S p0.001. Discussion: During radiotherapy sessions conducted outside of the operating room for children, the use of sevoflurane sedation was found to have a lower failure rate compared to intravenous sedation.

 Aim: Childhood cancers are often treated with radiotherapy. During radiation therapy, sedation is often required for immobilization, especially for young children and patients with mental disabilities. Our study aimed to compare the efficacy of sevoflurane insufflation and intravenous ketamine for sedation during pediatric radiotherapy. Materials and methods: This prospective, randomized, cross-over study was conducted between August and December 2020 on pediatric patients 1 month to 18 years requiring sedation or general anesthesia for radiotherapy. 352 repeated sessions were conducted in the study involving 18 patients who participated. Two groups were categorized by session: ketamine Group K or sevoflurane Group S. Results: The study included the evaluation of 352 sessions for 18 patients Although there was no significant difference in procedure times between Group S and Group K during the sessions p0.05, Group K showed a significantly longer discharge time, higher failure rate, and higher score sedation scale in comparison to Group S p0.001. Discussion: During radiotherapy sessions conducted outside of the operating room for children, the use of sevoflurane sedation was found to have a lower failure rate compared to intravenous sedation.

 Aim: Childhood cancers are often treated with radiotherapy. During radiation therapy, sedation is often required for immobilization, especially for young children and patients with mental disabilities. Our study aimed to compare the efficacy of sevoflurane insufflation and intravenous ketamine for sedation during pediatric radiotherapy. Materials and methods: This prospective, randomized, cross-over study was conducted between August and December 2020 on pediatric patients 1 month to 18 years requiring sedation or general anesthesia for radiotherapy. 352 repeated sessions were conducted in the study involving 18 patients who participated. Two groups were categorized by session: ketamine Group K or sevoflurane Group S. Results: The study included the evaluation of 352 sessions for 18 patients Although there was no significant difference in procedure times between Group S and Group K during the sessions p0.05, Group K showed a significantly longer discharge time, higher failure rate, and higher score sedation scale in comparison to Group S p0.001. Discussion: During radiotherapy sessions conducted outside of the operating room for children, the use of sevoflurane sedation was found to have a lower failure rate compared to intravenous sedation.

 Amaç: Çocukluk çağı kanserleri sıklıkla radyoterapi ile tedavi edilir. Radyasyon tedavisi sırasında, özellikle küçük çocuklarda ve zihinsel engelli hastalarda immobilizasyon için sıklıkla sedasyon gereklidir. Çalışmamızda pediatrik radyoterapi sırasında sedasyon için sevofluran insuflasyonu ve intravenöz ketaminin etkinliğini karşılaştırmayı amaçladık. Gereç ve yöntemler: Bu prospektif, randomize, cross-over çalışma Ağustos-Aralık 2020 tarihleri arasında radyoterapi için sedasyon veya genel anestezi gerektiren pediatrik hastalarda 1 ay-18 yaş yürütüldü. 18 hastanın katıldığı çalışmada 352 tekrarlı seans gerçekleştirilmiştir. Seanslara göre iki grup kategorize edilmiştir: ketamin Grup K veya sevofluran Grup S. Sonuçlar: Çalışma 18 hasta için 352 seansın değerlendirilmesini içeriyordu. Seanslar sırasında Grup S ve Grup K arasında işlem süreleri açısından anlamlı bir fark olmamasına rağmen p0.05, Grup K, Grup Sye kıyasla anlamlı olarak daha uzun taburcu süresi, daha yüksek başarısızlık oranı ve daha yüksek sedasyon skoru gösterdi p0.001. Tartışma: Çocuklarda ameliyathane dışında yapılan radyoterapi seansları sırasında sevofluran sedasyon kullanımının intravenöz sedasyona kıyasla daha düşük başarısızlık oranına sahip olduğu bulunmuştur.

Makale detayları

Comparison of sevoflurane insufflation and intravenous ketamine use in terms of failure rate in consecutive paediatrıc radiotherapy sessions: a cross-over study

Yazarlar:

Betül Güven Aytaç

Yayıncı:

MediHealth Academy Yayıncılık

Ana Başlıklar:

Anesteziyoloji

Dergi:

Journal of Medicine and Palliative Care Vol.4 Issue 5, pp.591-595

Belge Tipi:

Makale

Yayın Tarihi:

10/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001302599

pISSN:

2717-7505

Nonoperating room sedation

Sevoflurane

Ketamine

Radiotherapy

Childhood malignancies.Ameliyathane dışı sedasyon

Sevofluran

Ketamin

Radyoterapi

Çocukluk çağı maligniteleri.

Sayı

Makale detayları

Yazarlar: Betül Güven Aytaç

Yayıncı: MediHealth Academy Yayıncılık

Ana Başlıklar: Anesteziyoloji

Dergi: Journal of Medicine and Palliative Care Vol.4 Issue 5, pp.591-595

Belge Tipi: Makale

Yayın Tarihi: 10/2023

Belge Dili: İngilizce

Document ID (Org No.): 2001302599

pISSN: 2717-7505

Sayı

Yazarlar:

Betül Güven Aytaç

Yayıncı:

MediHealth Academy Yayıncılık

Ana Başlıklar:

Anesteziyoloji

Dergi:

Journal of Medicine and Palliative Care Vol.4 Issue 5, pp.591-595

Belge Tipi:

Makale

Yayın Tarihi:

10/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001302599

pISSN:

2717-7505