Clinical Significance of CRP/Albumin Value on Hospitalization and Length of Hospital Stay of Patients with Coronavirus-19: A Prospective Study

Uğur Lök; Umut Gülaçtı; Hüseyin Kafadar; Hakan Kaya

Makale detayları

Clinical Significance of CRP/Albumin Value on Hospitalization and Length of Hospital Stay of Patients with Coronavirus-19: A Prospective Study

Yazarlar:

Uğur Lök | Umut Gülaçtı | Hüseyin Kafadar | Hakan Kaya

Yayıncı:

Kahramanmaras Sutcu Imam University

Ana Başlıklar:

Sağlık Kurumları Yönetimi

Dergi:

Kahramanmaraş Sütçü İmam Üniversitesi Tıp Fakültesi Dergisi Vol.18 Issue 2, pp.99-105

Belge Tipi:

Makale

Yayın Tarihi:

12/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001293227

pISSN:

1303-6610

Anahtar kelimeler:

Özet:

 Objective: To investigate the diagnostic and prognostic significance of the C-reactive protein-to-albumin ratio CAR in coronavirus disease 2019 COVID- 19 patients admitted for the first time to a hospital emergency department ED. Materials and methods: The study we report herein was a single-center, prospective observational study. A total of 745 participants 385 patients, 360 individuals were included in the study. The CAR was calculated by dividing the C-reactive protein CRP; mgL value by the albumin value gr. The data were analyzed using MedCalc Statistical Software v12.7.0.0 Ostend, Belgium and Students t-test, chi square test, and Pearsons correlation coefficient. A p-value of 0.05was considered statistically significant. Results: A total of 355 patients were hospitalized, and 30 of them were followed as outpatients. The mean CAR values of the hospitalized patients and the outpatients were 0.340.89 and 0.390.72 respectively 95 confidence interval CI: -0.31 to 0.40; p0.796. A 309 patients were hospitalized in wards and 46, in intensive care units; their mean CAR values were 0.330.92 and 0.440.74, respectively 95 CI: -0.17 to 0.39; p0.449. As the CAR value increased, the length of hospital stay also increased p0.0001. At the best cut-off point for COVID-19 diagnosis, CAR was shown to have 82.66 specificity, 69.72 sensitivity, 4.02 positive likelihood, and 0.37 negative likelihood. Conclusion: The length of stay in the hospital of the COVID-19 patients in the study was closely related to their CAR values obtained at the time of their first ED admission.s closely related to their CAR values obtained at the time of their first ED admission.

 Objective: To investigate the diagnostic and prognostic significance of the C-reactive protein-to-albumin ratio CAR in coronavirus disease 2019 COVID- 19 patients admitted for the first time to a hospital emergency department ED. Materials and methods: The study we report herein was a single-center, prospective observational study. A total of 745 participants 385 patients, 360 individuals were included in the study. The CAR was calculated by dividing the C-reactive protein CRP; mgL value by the albumin value gr. The data were analyzed using MedCalc Statistical Software v12.7.0.0 Ostend, Belgium and Students t-test, chi square test, and Pearsons correlation coefficient. A p-value of 0.05was considered statistically significant. Results: A total of 355 patients were hospitalized, and 30 of them were followed as outpatients. The mean CAR values of the hospitalized patients and the outpatients were 0.340.89 and 0.390.72 respectively 95 confidence interval CI: -0.31 to 0.40; p0.796. A 309 patients were hospitalized in wards and 46, in intensive care units; their mean CAR values were 0.330.92 and 0.440.74, respectively 95 CI: -0.17 to 0.39; p0.449. As the CAR value increased, the length of hospital stay also increased p0.0001. At the best cut-off point for COVID-19 diagnosis, CAR was shown to have 82.66 specificity, 69.72 sensitivity, 4.02 positive likelihood, and 0.37 negative likelihood. Conclusion: The length of stay in the hospital of the COVID-19 patients in the study was closely related to their CAR values obtained at the time of their first ED admission.s closely related to their CAR values obtained at the time of their first ED admission.

 Objective: To investigate the diagnostic and prognostic significance of the C-reactive protein-to-albumin ratio CAR in coronavirus disease 2019 COVID- 19 patients admitted for the first time to a hospital emergency department ED. Materials and methods: The study we report herein was a single-center, prospective observational study. A total of 745 participants 385 patients, 360 individuals were included in the study. The CAR was calculated by dividing the C-reactive protein CRP; mgL value by the albumin value gr. The data were analyzed using MedCalc Statistical Software v12.7.0.0 Ostend, Belgium and Students t-test, chi square test, and Pearsons correlation coefficient. A p-value of 0.05was considered statistically significant. Results: A total of 355 patients were hospitalized, and 30 of them were followed as outpatients. The mean CAR values of the hospitalized patients and the outpatients were 0.340.89 and 0.390.72 respectively 95 confidence interval CI: -0.31 to 0.40; p0.796. A 309 patients were hospitalized in wards and 46, in intensive care units; their mean CAR values were 0.330.92 and 0.440.74, respectively 95 CI: -0.17 to 0.39; p0.449. As the CAR value increased, the length of hospital stay also increased p0.0001. At the best cut-off point for COVID-19 diagnosis, CAR was shown to have 82.66 specificity, 69.72 sensitivity, 4.02 positive likelihood, and 0.37 negative likelihood. Conclusion: The length of stay in the hospital of the COVID-19 patients in the study was closely related to their CAR values obtained at the time of their first ED admission.s closely related to their CAR values obtained at the time of their first ED admission.

 Amaç: İlk tanısı acil servis te yapılan Koronavirüs 2019 COVID-19 hastalarda C- reaktif proteinalbümin oranının CAR tanısal ve prognostik önemini araştırması. Gereç ve Yöntemler: Burada sunduğumuz çalışma, tek merkezli, ileriye dönük gözlemsel bir çalışmadır. Çalışmaya toplam 745 katılımcı 385 hasta, 360 kişi dâhil edildi. CAR, C-reaktif protein CRP; mgL değerinin albümin değerine gr bölünmesiyle hesaplandı. Veriler MedCalc İstatistik Yazılımı v12.7.0.0 Oostende, Belçika ve Student t testi, ki kare testi ve Pearson korelasyon katsayısı kullanılarak analiz edildi. p0.05 değeri istatistiksel olarak anlamlı kabul edildi. Bulgular: Toplam 355 hasta yatarak tedavi edildi ve bunların 30u ayaktan takip edildi. Hastanede yatan hastaların ve ayaktan hastaların ortalama CAR değerleri sırasıyla 0.340.89 ve 0.390.72 idi 95 güven aralığı GA: -0.31 ila 0.40; p  0.796. 309 hasta koğuşlarda, 46 hasta ise yoğun bakım ünitelerinde tedavi edilirken; ortalama CAR değerleri sırasıyla 0.330.92 ve 0.440.74 idi 95 GA: -0.17 ila 0.39; p0.449. CAR değeri arttıkça hastanede kalış süresi de arttı p 0,0001. COVID-19 teşhisi için en iyi kesme noktasında CARın 82.66 özgüllük, 69.72 duyarlılık, 4.02 pozitif olasılık ve 0.37 negatif olasılığa sahip olduğu gösterildi. Sonuç: Çalışmadaki COVID-19 hastalarının hastanede kalış süresi, ilk acil servise başvuru anında tespit edilen CAR değerleri ile yakından ilişkiliydi.rının hastanede kalış süresi, ilk acil servise başvuru anında tespit edilen CAR değerleri ile yakından ilişkiliydi.

Makale detayları

Clinical Significance of CRP/Albumin Value on Hospitalization and Length of Hospital Stay of Patients with Coronavirus-19: A Prospective Study

Yazarlar:

Uğur Lök | Umut Gülaçtı | Hüseyin Kafadar | Hakan Kaya

Yayıncı:

Kahramanmaras Sutcu Imam University

Ana Başlıklar:

Sağlık Kurumları Yönetimi

Dergi:

Kahramanmaraş Sütçü İmam Üniversitesi Tıp Fakültesi Dergisi Vol.18 Issue 2, pp.99-105

Belge Tipi:

Makale

Yayın Tarihi:

12/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001293227

pISSN:

1303-6610

Coronavirus disease 2019

C reactive protein to albumin ratio

first admission

hospital stayCoronavirus disease 2019

C reactive protein to albumin ratio

first admission

hospital stay

Coronavirüs hastalığı 2019

C-reaktif protein/albümin oranı

ilk başvuru

hastanede kalış süresi

Sayı

Makale detayları

Yazarlar: Uğur Lök | Umut Gülaçtı | Hüseyin Kafadar | Hakan Kaya

Yayıncı: Kahramanmaras Sutcu Imam University

Ana Başlıklar: Sağlık Kurumları Yönetimi

Dergi: Kahramanmaraş Sütçü İmam Üniversitesi Tıp Fakültesi Dergisi Vol.18 Issue 2, pp.99-105

Belge Tipi: Makale

Yayın Tarihi: 12/2023

Belge Dili: İngilizce

Document ID (Org No.): 2001293227

pISSN: 1303-6610

Sayı

Yazarlar:

Uğur Lök | Umut Gülaçtı | Hüseyin Kafadar | Hakan Kaya

Yayıncı:

Kahramanmaras Sutcu Imam University

Ana Başlıklar:

Sağlık Kurumları Yönetimi

Dergi:

Kahramanmaraş Sütçü İmam Üniversitesi Tıp Fakültesi Dergisi Vol.18 Issue 2, pp.99-105

Belge Tipi:

Makale

Yayın Tarihi:

12/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001293227

pISSN:

1303-6610