Analysis of anti-aging activity of Chinese perfume (Aglaia  odorata) and Indian camphorweed (Pluchea indica) leaves  using Saccharomyces cerevisiae model system

N.A.

Makale detayları

Analysis of anti-aging activity of Chinese perfume (Aglaia odorata) and Indian camphorweed (Pluchea indica) leaves using Saccharomyces cerevisiae model system

Yazarlar:

N.A.

Yayıncı:

Marmara University

Ana Başlıklar:

Pharmacology and Pharmaceutical Sciences (Other)

Dergi:

Journal of Research in Pharmacy Vol.29 Issue 1, pp.396-406

Belge Tipi:

Makale

Yayın Tarihi:

3/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001339630

pISSN:

2630-6344

Anahtar kelimeler:

Özet:

 This study examined the anti-aging effect of Chinese perfume Aglaia odorata and Indian camphorweed Pluchea indica leaf extracts on Saccharomyces cerevisiae as a model system. Investigation of the antioxidant activity and bioactive compounds using GCMS and qualitative anti-aging spot tests were performed to determine the anti-aging effects. In addition, a quantitative anti-aging test was conducted using high-throughput chronological lifespan analysis. The results showed that the antioxidant enzyme activities of SOD, APX, and CAT in Chinese perfume leaves were 393.96 unitsming FW, 215 µmoles H2O2ming FW, and 5.6 µmoles H2O2 decomposedming FW, respectively; the values in Indian camphorweed leaves were 717.57 unitsming FW, 48 µmoles H2O2ming FW, and 12.33 µmole H2O2 decomposedming FW, respectively. The antioxidant activity of Chinese perfume and Indian camphorweed was 577.2 µgmL and 348.86 µgmL. The antioxidant bioactive compounds of Chinese perfume extract included n-hexadecanoic acid, β turmerone, and 2-propenoic acid, 3-phenyl-, methyl ester methyl cinnamate and those from Indian camphorweed included n-hexadecanoic acid and neophytadiene. Treatment with both extracts prolonged the life of yeast after 15 days of incubation. In addition, H2O2 stress conditions, the yeasts showed better growth with the addition of both leaf extracts. This study revealed that the extracts of Chinese perfume and Indian camphorweed leaves demonstrate promising potential as ingredients for anti-aging cosmetics.

 This study examined the anti-aging effect of Chinese perfume Aglaia odorata and Indian camphorweed Pluchea indica leaf extracts on Saccharomyces cerevisiae as a model system. Investigation of the antioxidant activity and bioactive compounds using GCMS and qualitative anti-aging spot tests were performed to determine the anti-aging effects. In addition, a quantitative anti-aging test was conducted using high-throughput chronological lifespan analysis. The results showed that the antioxidant enzyme activities of SOD, APX, and CAT in Chinese perfume leaves were 393.96 unitsming FW, 215 µmoles H2O2ming FW, and 5.6 µmoles H2O2 decomposedming FW, respectively; the values in Indian camphorweed leaves were 717.57 unitsming FW, 48 µmoles H2O2ming FW, and 12.33 µmole H2O2 decomposedming FW, respectively. The antioxidant activity of Chinese perfume and Indian camphorweed was 577.2 µgmL and 348.86 µgmL. The antioxidant bioactive compounds of Chinese perfume extract included n-hexadecanoic acid, β turmerone, and 2-propenoic acid, 3-phenyl-, methyl ester methyl cinnamate and those from Indian camphorweed included n-hexadecanoic acid and neophytadiene. Treatment with both extracts prolonged the life of yeast after 15 days of incubation. In addition, H2O2 stress conditions, the yeasts showed better growth with the addition of both leaf extracts. This study revealed that the extracts of Chinese perfume and Indian camphorweed leaves demonstrate promising potential as ingredients for anti-aging cosmetics.

 This study examined the anti-aging effect of Chinese perfume Aglaia odorata and Indian camphorweed Pluchea indica leaf extracts on Saccharomyces cerevisiae as a model system. Investigation of the antioxidant activity and bioactive compounds using GCMS and qualitative anti-aging spot tests were performed to determine the anti-aging effects. In addition, a quantitative anti-aging test was conducted using high-throughput chronological lifespan analysis. The results showed that the antioxidant enzyme activities of SOD, APX, and CAT in Chinese perfume leaves were 393.96 unitsming FW, 215 µmoles H2O2ming FW, and 5.6 µmoles H2O2 decomposedming FW, respectively; the values in Indian camphorweed leaves were 717.57 unitsming FW, 48 µmoles H2O2ming FW, and 12.33 µmole H2O2 decomposedming FW, respectively. The antioxidant activity of Chinese perfume and Indian camphorweed was 577.2 µgmL and 348.86 µgmL. The antioxidant bioactive compounds of Chinese perfume extract included n-hexadecanoic acid, β turmerone, and 2-propenoic acid, 3-phenyl-, methyl ester methyl cinnamate and those from Indian camphorweed included n-hexadecanoic acid and neophytadiene. Treatment with both extracts prolonged the life of yeast after 15 days of incubation. In addition, H2O2 stress conditions, the yeasts showed better growth with the addition of both leaf extracts. This study revealed that the extracts of Chinese perfume and Indian camphorweed leaves demonstrate promising potential as ingredients for anti-aging cosmetics.

 This study examined the anti-aging effect of Chinese perfume Aglaia odorata and Indian camphorweed Pluchea indica leaf extracts on Saccharomyces cerevisiae as a model system. Investigation of the antioxidant activity and bioactive compounds using GCMS and qualitative anti-aging spot tests were performed to determine the anti-aging effects. In addition, a quantitative anti-aging test was conducted using high-throughput chronological lifespan analysis. The results showed that the antioxidant enzyme activities of SOD, APX, and CAT in Chinese perfume leaves were 393.96 unitsming FW, 215 µmoles H2O2ming FW, and 5.6 µmoles H2O2 decomposedming FW, respectively; the values in Indian camphorweed leaves were 717.57 unitsming FW, 48 µmoles H2O2ming FW, and 12.33 µmole H2O2 decomposedming FW, respectively. The antioxidant activity of Chinese perfume and Indian camphorweed was 577.2 µgmL and 348.86 µgmL. The antioxidant bioactive compounds of Chinese perfume extract included n-hexadecanoic acid, β turmerone, and 2-propenoic acid, 3-phenyl-, methyl ester methyl cinnamate and those from Indian camphorweed included n-hexadecanoic acid and neophytadiene. Treatment with both extracts prolonged the life of yeast after 15 days of incubation. In addition, H2O2 stress conditions, the yeasts showed better growth with the addition of both leaf extracts. This study revealed that the extracts of Chinese perfume and Indian camphorweed leaves demonstrate promising potential as ingredients for anti-aging cosmetics.

Makale detayları

Analysis of anti-aging activity of Chinese perfume (Aglaia odorata) and Indian camphorweed (Pluchea indica) leaves using Saccharomyces cerevisiae model system

Yazarlar:

N.A.

Yayıncı:

Marmara University

Ana Başlıklar:

Pharmacology and Pharmaceutical Sciences (Other)

Dergi:

Journal of Research in Pharmacy Vol.29 Issue 1, pp.396-406

Belge Tipi:

Makale

Yayın Tarihi:

3/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001339630

pISSN:

2630-6344

Chinese perfume

Indian camphorweed

anti-aging

antioxidant

S. cerevisiae

Sayı

Makale detayları

Analysis of anti-aging activity of Chinese perfume (Aglaia odorata) and Indian camphorweed (Pluchea indica) leaves using Saccharomyces cerevisiae model system

Yazarlar: N.A.

Yayıncı: Marmara University

Ana Başlıklar: Pharmacology and Pharmaceutical Sciences (Other)

Dergi: Journal of Research in Pharmacy Vol.29 Issue 1, pp.396-406

Belge Tipi: Makale

Yayın Tarihi: 3/2025

Belge Dili: İngilizce

Document ID (Org No.): 2001339630

pISSN: 2630-6344

Chinese perfume

Indian camphorweed

anti-aging

antioxidant

S. cerevisiae

Sayı

Yazarlar:

N.A.

Yayıncı:

Marmara University

Ana Başlıklar:

Pharmacology and Pharmaceutical Sciences (Other)

Dergi:

Journal of Research in Pharmacy Vol.29 Issue 1, pp.396-406

Belge Tipi:

Makale

Yayın Tarihi:

3/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001339630

pISSN:

2630-6344