Determination of plasma fibrinogen and haptoglobin, hematological and blood biochemical changes in Bulgarian local goats with experimentally induced Staphylococcus aureus mastitis

İvan FASULKOV; Manol KARADAEV; Nasko VASILEV; Valentina URUMOVA; Teodora MIRCHEVA

Makale detayları

Determination of plasma fibrinogen and haptoglobin, hematological and blood biochemical changes in Bulgarian local goats with experimentally induced Staphylococcus aureus mastitis

Yazarlar:

İvan FASULKOV | Manol KARADAEV | Nasko VASILEV | Valentina URUMOVA | Teodora MIRCHEVA

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Veterinary and Animal Sciences 2014 Vol.38 Issue 4, pp.439-444

Belge Tipi:

Makale

Yayın Tarihi:

3/2014

Belge Dili:

Türkçe

Document ID (Org No.):

2000765958

Sıklık:

İki Aylık

eISSN:

1303-6181

pISSN:

1300-0128

Anahtar kelimeler:

Özet:

 

The aim of the present study was to assess changes in acute phase proteins fibrinogen and haptoglobin, as well as hematological, blood biochemical, and microbiological alterations in local Bulgarian goats with experimentally induced Staphylococcus aureus mastitis. The experiments were conducted with 6 clinically healthy local Bulgarian goats, 2 to 6 years of age, weighing 46-57 kg. The experimental infection was done with a stationary phase culture of a field Staphylococcus aureus strain isolated from a cow with clinical mastitis. Blood haptoglobin in goats was considerably higher (P < 0.05) as early as 8 h after the pathogen's inoculation. The most significant differences from baseline values occurred 24 and 48 h (P < 0.01) after infection. Plasma fibrinogen increased significantly (P < 0.05) 8 h after infection and reached the highest mean concentration (9.12 g/L) by 72 h. Leukocytosis was established as early as 4 h after the experimental infection when leukocyte counts were significantly higher than baseline (P < 0.001). The analysis of results indicates that in experimentally induced Staphylococcus aureus mastitis, significantly higher (P < 0.05) levels of the leukocyte, fibrinogen, and haptoglobin are established as early as 8 h after the infection.

 

The aim of the present study was to assess changes in acute phase proteins fibrinogen and haptoglobin, as well as hematological, blood biochemical, and microbiological alterations in local Bulgarian goats with experimentally induced Staphylococcus aureus mastitis. The experiments were conducted with 6 clinically healthy local Bulgarian goats, 2 to 6 years of age, weighing 46-57 kg. The experimental infection was done with a stationary phase culture of a field Staphylococcus aureus strain isolated from a cow with clinical mastitis. Blood haptoglobin in goats was considerably higher (P < 0.05) as early as 8 h after the pathogen's inoculation. The most significant differences from baseline values occurred 24 and 48 h (P < 0.01) after infection. Plasma fibrinogen increased significantly (P < 0.05) 8 h after infection and reached the highest mean concentration (9.12 g/L) by 72 h. Leukocytosis was established as early as 4 h after the experimental infection when leukocyte counts were significantly higher than baseline (P < 0.001). The analysis of results indicates that in experimentally induced Staphylococcus aureus mastitis, significantly higher (P < 0.05) levels of the leukocyte, fibrinogen, and haptoglobin are established as early as 8 h after the infection.

Makale detayları

Determination of plasma fibrinogen and haptoglobin, hematological and blood biochemical changes in Bulgarian local goats with experimentally induced Staphylococcus aureus mastitis

Yazarlar:

İvan FASULKOV | Manol KARADAEV | Nasko VASILEV | Valentina URUMOVA | Teodora MIRCHEVA

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Veterinary and Animal Sciences 2014 Vol.38 Issue 4, pp.439-444

Belge Tipi:

Makale

Yayın Tarihi:

3/2014

Belge Dili:

Türkçe

Document ID (Org No.):

2000765958

Sıklık:

İki Aylık

eISSN:

1303-6181

pISSN:

1300-0128

Acute phase proteins

goats

mastitis

Sayı

Makale detayları

Determination of plasma fibrinogen and haptoglobin, hematological and blood biochemical changes in Bulgarian local goats with experimentally induced Staphylococcus aureus mastitis

Yazarlar: İvan FASULKOV | Manol KARADAEV | Nasko VASILEV | Valentina URUMOVA | Teodora MIRCHEVA

Yayıncı: TUBITAK

Dergi: Turkish Journal of Veterinary and Animal Sciences 2014 Vol.38 Issue 4, pp.439-444

Belge Tipi: Makale

Yayın Tarihi: 3/2014

Belge Dili: Türkçe

Document ID (Org No.): 2000765958

Sıklık: İki Aylık

eISSN: 1303-6181

pISSN: 1300-0128

Acute phase proteins

goats

mastitis

Sayı

Yazarlar:

İvan FASULKOV | Manol KARADAEV | Nasko VASILEV | Valentina URUMOVA | Teodora MIRCHEVA

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Veterinary and Animal Sciences 2014 Vol.38 Issue 4, pp.439-444

Belge Tipi:

Makale

Yayın Tarihi:

3/2014

Belge Dili:

Türkçe

Document ID (Org No.):

2000765958

Sıklık:

İki Aylık

eISSN:

1303-6181

pISSN:

1300-0128