Outcomes of liver transplantation patients infected with COVID-19: pandemic hospital experience from Turkey

Taner Akyol; Tolga Düzenli

Makale detayları

Outcomes of liver transplantation patients infected with COVID-19: pandemic hospital experience from Turkey

Yazarlar:

Taner Akyol | Tolga Düzenli

Yayıncı:

MediHealth Academy Yayıncılık

Ana Başlıklar:

Gastroenteroloji ve Hepatoloji

Dergi:

Journal of Health Sciences and Medicine Vol.6 Issue 6, pp.1154-1157

Belge Tipi:

Makale

Yayın Tarihi:

10/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001303040

pISSN:

2636-8579

Anahtar kelimeler:

Özet:

 Aims: There are conflicting results for the course of the disease and mortality rates for liver transplantation patients infected with COVID-19. In this study, we aimed to present the outcomes of our liver transplant patients who were hospitalized and followed up in our tertiary hospital, which served as a pandemic hospital for COVID-19. Methods: Patients hospitalized with the diagnosis of COVID-19 between March 1, 2020 and March 1, 2022 in Sancaktepe Şehit Prof. Dr. İlhan Varank Training and Research Hospital and Prof. Dr. Feriha Öz Pandemic Hospital were included. In this retrospective observational study, the clinical data of the patients, the need for intensive care hospitalization, and mortality rates were recorded by hospital computer system. The relationships were analyzed with SPSS v20.0. Results: There were 25996 patients who were hospitalized with the diagnosis of COVID-19 and 28 of them were with the history of liver transplantation. Ages of the liver transplant patients ranged from 18 to 73, with a median age of 52. 82.1 of the patients were male and 17.9 were female. Intensive care unit hospitalization rate was 25 and mortality rate was 14.3. The relationships according to the age groups revealed that all of the women were under the age of 50 p0.008 and the patients who deceased were male patients over the age of 50 p0.044. Conclusion: Mortality rates and intensive care unit requirements of chronically immunosuppressed liver transplant patients with COVID-19 infection were similar with general population. Complete immunosuppression withdrawal should not be urged in this population.

 Aims: There are conflicting results for the course of the disease and mortality rates for liver transplantation patients infected with COVID-19. In this study, we aimed to present the outcomes of our liver transplant patients who were hospitalized and followed up in our tertiary hospital, which served as a pandemic hospital for COVID-19. Methods: Patients hospitalized with the diagnosis of COVID-19 between March 1, 2020 and March 1, 2022 in Sancaktepe Şehit Prof. Dr. İlhan Varank Training and Research Hospital and Prof. Dr. Feriha Öz Pandemic Hospital were included. In this retrospective observational study, the clinical data of the patients, the need for intensive care hospitalization, and mortality rates were recorded by hospital computer system. The relationships were analyzed with SPSS v20.0. Results: There were 25996 patients who were hospitalized with the diagnosis of COVID-19 and 28 of them were with the history of liver transplantation. Ages of the liver transplant patients ranged from 18 to 73, with a median age of 52. 82.1 of the patients were male and 17.9 were female. Intensive care unit hospitalization rate was 25 and mortality rate was 14.3. The relationships according to the age groups revealed that all of the women were under the age of 50 p0.008 and the patients who deceased were male patients over the age of 50 p0.044. Conclusion: Mortality rates and intensive care unit requirements of chronically immunosuppressed liver transplant patients with COVID-19 infection were similar with general population. Complete immunosuppression withdrawal should not be urged in this population.

 Aims: There are conflicting results for the course of the disease and mortality rates for liver transplantation patients infected with COVID-19. In this study, we aimed to present the outcomes of our liver transplant patients who were hospitalized and followed up in our tertiary hospital, which served as a pandemic hospital for COVID-19. Methods: Patients hospitalized with the diagnosis of COVID-19 between March 1, 2020 and March 1, 2022 in Sancaktepe Şehit Prof. Dr. İlhan Varank Training and Research Hospital and Prof. Dr. Feriha Öz Pandemic Hospital were included. In this retrospective observational study, the clinical data of the patients, the need for intensive care hospitalization, and mortality rates were recorded by hospital computer system. The relationships were analyzed with SPSS v20.0. Results: There were 25996 patients who were hospitalized with the diagnosis of COVID-19 and 28 of them were with the history of liver transplantation. Ages of the liver transplant patients ranged from 18 to 73, with a median age of 52. 82.1 of the patients were male and 17.9 were female. Intensive care unit hospitalization rate was 25 and mortality rate was 14.3. The relationships according to the age groups revealed that all of the women were under the age of 50 p0.008 and the patients who deceased were male patients over the age of 50 p0.044. Conclusion: Mortality rates and intensive care unit requirements of chronically immunosuppressed liver transplant patients with COVID-19 infection were similar with general population. Complete immunosuppression withdrawal should not be urged in this population.

 Aims: There are conflicting results for the course of the disease and mortality rates for liver transplantation patients infected with COVID-19. In this study, we aimed to present the outcomes of our liver transplant patients who were hospitalized and followed up in our tertiary hospital, which served as a pandemic hospital for COVID-19. Methods: Patients hospitalized with the diagnosis of COVID-19 between March 1, 2020 and March 1, 2022 in Sancaktepe Şehit Prof. Dr. İlhan Varank Training and Research Hospital and Prof. Dr. Feriha Öz Pandemic Hospital were included. In this retrospective observational study, the clinical data of the patients, the need for intensive care hospitalization, and mortality rates were recorded by hospital computer system. The relationships were analyzed with SPSS v20.0. Results: There were 25996 patients who were hospitalized with the diagnosis of COVID-19 and 28 of them were with the history of liver transplantation. Ages of the liver transplant patients ranged from 18 to 73, with a median age of 52. 82.1 of the patients were male and 17.9 were female. Intensive care unit hospitalization rate was 25 and mortality rate was 14.3. The relationships according to the age groups revealed that all of the women were under the age of 50 p0.008 and the patients who deceased were male patients over the age of 50 p0.044. Conclusion: Mortality rates and intensive care unit requirements of chronically immunosuppressed liver transplant patients with COVID-19 infection were similar with general population. Complete immunosuppression withdrawal should not be urged in this population.

Makale detayları

Outcomes of liver transplantation patients infected with COVID-19: pandemic hospital experience from Turkey

Yazarlar: Taner Akyol | Tolga Düzenli

Yayıncı: MediHealth Academy Yayıncılık

Ana Başlıklar: Gastroenteroloji ve Hepatoloji

Dergi: Journal of Health Sciences and Medicine Vol.6 Issue 6, pp.1154-1157

Belge Tipi: Makale

Yayın Tarihi: 10/2023

Belge Dili: İngilizce

Document ID (Org No.): 2001303040

pISSN: 2636-8579

COVID-19

infection

liver

mortality

transplantation

Sayı

Yazarlar:

Taner Akyol | Tolga Düzenli

Yayıncı:

MediHealth Academy Yayıncılık

Ana Başlıklar:

Gastroenteroloji ve Hepatoloji

Dergi:

Journal of Health Sciences and Medicine Vol.6 Issue 6, pp.1154-1157

Belge Tipi:

Makale

Yayın Tarihi:

10/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001303040

pISSN:

2636-8579