Susceptibility-Weighted Imaging In Grading of Infiltrative Glial Tumors

Firuze OCAK; Mehmet Erdem YILDIZ; Alp DİNÇER

Makale detayları

Susceptibility-Weighted Imaging In Grading of Infiltrative Glial Tumors

Yazarlar:

Firuze OCAK | Mehmet Erdem YILDIZ | Alp DİNÇER

Dergi:

Acıbadem Üniversitesi Sağlık Bilimleri Dergisi 2020 Issue 3, pp.488-493

Belge Tipi:

Makale

Yayın Tarihi:

8/2020

Belge Dili:

İngilizce

Document ID (Org No.):

2000438703

Özet:

 

Purpose: Histopathological and radiological examination is necessary for the evaluation of tumor types and staging. Histopathologic examination is considered as the gold standard, while the radiological examination is used for preoperative evaluation. The purpose of the present study was to evaluate susceptibility-weighted imaging  SWI  the in grading of infiltrative glial tumors.Materials and Methods: The SWI sequences in pre-operative magnetic resonance imaging  MRI  images were retrospectively assessed in a total of 67 patients  mean age, 36.7 years; age range, 4–79 years; 29 female, 38 male  who were diagnosed with a glial tumor based on histopathological examination. The numbers of punctate intratumoral susceptibility sign  ITSS  in the SWI sequence in the tumors were determined by two radiologists on a consensus-based approach. Lesions with no ITSS were graded as Grade 0, while those having 1–5, 6–15, >15 ITSS were categorized as Grade 1, Grade 2, and Grade 3, respectively. No susceptibility was classified as ITSS, “non-punctate with blurred margins” and diffuse susceptibility were categorized as >15. ITSS grades were compared to the results of histopathological grading and diagnosis.Results: The sensitivity, specificity, negative predictive value, and positive predictive value of the presence of ITSS regarding differentiating high and low-grade glial tumors were 97.6%, 88%, 95.65%, and 93.18%, respectively.Conclusion: In diffuse glial tumors, while the presence of ITSS is indicative of high-grade tumors, its absence is associated with low-grade tumors. These data suggest that the presence rather than the number of ITSS yields more information on the grade of this type of tumor.

 

Amaç: Tümör tipleri ve evrelendirme için histopatolojik ve radyolojik inceleme gereklidir. Histopatolojik inceleme altın  standart olarak kabul edilirken, preoperatif değerlendirme için radyolojik inceleme kullanılır. Bu çalışmanın amacı infiltratif glial tümörlerin evrelemesinde susceptibility ağırlıklı görüntülemenin  SWI  değerlendirilmesidir.  Materyal ve Metot: Patolojik olarak glial tümör tanısı konmuş 67 hastanın  4–79 yaş, yaş ortalaması 36,7; 29 kadın ve  38 erkek  retrospektif olarak preoperatif MRG görüntülemelerindeki SWI sekansları değerlendirilmiştir. Tüm tümörlerin  SWI sekansında izlenen punktat ITSS  intratumoral susceptibility sign  sayıları iki radyolog tarafından konsensusla patolojik tanıları bilinmeden kör olarak hesaplanmıştır. Hiç ITSS içermeyen lezyonlar ITSS Evre 0, 1–5 ITSS içeren lezyonlar  ITSS Evre 1, 6–15 ITSS içeren lezyonlar ITSS Evre 2, 15.

Makale detayları

Susceptibility-Weighted Imaging In Grading of Infiltrative Glial Tumors

Yazarlar: Firuze OCAK | Mehmet Erdem YILDIZ | Alp DİNÇER

Dergi: Acıbadem Üniversitesi Sağlık Bilimleri Dergisi 2020 Issue 3, pp.488-493

Belge Tipi: Makale

Yayın Tarihi: 8/2020

Belge Dili: İngilizce

Document ID (Org No.): 2000438703

Sayı

Yazarlar:

Firuze OCAK | Mehmet Erdem YILDIZ | Alp DİNÇER

Dergi:

Acıbadem Üniversitesi Sağlık Bilimleri Dergisi 2020 Issue 3, pp.488-493

Belge Tipi:

Makale

Yayın Tarihi:

8/2020

Belge Dili:

İngilizce

Document ID (Org No.):

2000438703