Splenic hemangiosarcoma with abdominal dissemination in a dog

M. Yavuz GÜLBAHAR

Makale detayları

Splenic hemangiosarcoma with abdominal dissemination in a dog

Yazarlar:

M. Yavuz GÜLBAHAR

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Veterinary and Animal Sciences 1998 Vol.22 Issue 5, pp.459-464

Belge Tipi:

Makale

Yayın Tarihi:

4/1998

Belge Dili:

Türkçe

Document ID (Org No.):

2000772511

Sıklık:

İki Aylık

eISSN:

1303-6181

pISSN:

1300-0128

Anahtar kelimeler:

Özet:

 

A case of spontaneosly ruptured splenic hemangiosarcoma with abdominal dissemination in a 12-year-old male German  shepherd dog is described. At necropsy, a ruptured tumor mass was seen in the ventral region of the visceral surface of the spleen,  and disseminated tumor masses were seen throughout the peritoneal cavity. Histologically, in both the primary tumor mass and dis-seminated  tumor masses, atypical endothelial cells lining vascular spaces as small clefts or as cavernous channels were observed.  Some immunological properties of tumor cells were determined for endothelial cell markers (factor VII-related antigen=von  Willebrand's factor [vWf] and CD31 antigen), mesenchymal tissue marker (vimentin) and pericyte-smooth muscle marker (a-smooth  muscle actin [a-SMA]). Tumor cells were positive for CD31, vimentin and a -SMA, whereas they were negative for vWf. According  to morphological and immunohistochemical results, this case was diagnosed as hemangiosarcoma arising from the spleen with  abdominal dissemination.

 

A case of spontaneosly ruptured splenic hemangiosarcoma with abdominal dissemination in a 12-year-old male German  shepherd dog is described. At necropsy, a ruptured tumor mass was seen in the ventral region of the visceral surface of the spleen,  and disseminated tumor masses were seen throughout the peritoneal cavity. Histologically, in both the primary tumor mass and dis-seminated  tumor masses, atypical endothelial cells lining vascular spaces as small clefts or as cavernous channels were observed.  Some immunological properties of tumor cells were determined for endothelial cell markers (factor VII-related antigen=von  Willebrand's factor [vWf] and CD31 antigen), mesenchymal tissue marker (vimentin) and pericyte-smooth muscle marker (a-smooth  muscle actin [a-SMA]). Tumor cells were positive for CD31, vimentin and a -SMA, whereas they were negative for vWf. According  to morphological and immunohistochemical results, this case was diagnosed as hemangiosarcoma arising from the spleen with  abdominal dissemination.

Makale detayları

Splenic hemangiosarcoma with abdominal dissemination in a dog

Yazarlar:

M. Yavuz GÜLBAHAR

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Veterinary and Animal Sciences 1998 Vol.22 Issue 5, pp.459-464

Belge Tipi:

Makale

Yayın Tarihi:

4/1998

Belge Dili:

Türkçe

Document ID (Org No.):

2000772511

Sıklık:

İki Aylık

eISSN:

1303-6181

pISSN:

1300-0128

Splenic hemangiosarcoma

dog

factor VIII-related antigen

CD31

vimentin

a-smooth muscle actin

Sayı

Makale detayları

Splenic hemangiosarcoma with abdominal dissemination in a dog

Yazarlar: M. Yavuz GÜLBAHAR

Yayıncı: TUBITAK

Dergi: Turkish Journal of Veterinary and Animal Sciences 1998 Vol.22 Issue 5, pp.459-464

Belge Tipi: Makale

Yayın Tarihi: 4/1998

Belge Dili: Türkçe

Document ID (Org No.): 2000772511

Sıklık: İki Aylık

eISSN: 1303-6181

pISSN: 1300-0128

Splenic hemangiosarcoma

dog

factor VIII-related antigen

CD31

vimentin

a-smooth muscle actin

Sayı

Yazarlar:

M. Yavuz GÜLBAHAR

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Veterinary and Animal Sciences 1998 Vol.22 Issue 5, pp.459-464

Belge Tipi:

Makale

Yayın Tarihi:

4/1998

Belge Dili:

Türkçe

Document ID (Org No.):

2000772511

Sıklık:

İki Aylık

eISSN:

1303-6181

pISSN:

1300-0128