Dinitro-Ortho-Cresol Maruziyeti Sonrasında Akut Koroner Sendrom GelişenArdışık İki Hasta

Ahmet Oğuz BAKTIR; Hayrettin SAĞLAM; Bahadır ŞARLI; Hüseyin ARINÇ; Yasemin DOĞAN; Hüseyin KATLANDUR

Makale detayları

Dinitro-Ortho-Cresol Maruziyeti Sonrasında Akut Koroner Sendrom GelişenArdışık İki Hasta

Yazarlar:

Ahmet Oğuz BAKTIR | Hayrettin SAĞLAM | Bahadır ŞARLI | Hüseyin ARINÇ | Yasemin DOĞAN | Hüseyin KATLANDUR

Yayıncı:

Acil Tıp Uzmanları Derneği

Dergi:

Journal of Emergency Medicine Case Reports 2013 Vol.4 Issue 4, pp.147-150

Belge Tipi:

Makale

Yayın Tarihi:

9/2013

Belge Dili:

Türkçe

Document ID (Org No.):

2000505059

Sıklık:

Aylık

eISSN:

2149-9934

Özet:

 

Nitrophenols are common components of industrial effluents and have been detected in urban and agricultural waste. Dinitroortho-cresol (DNOC) can easily enter the body through inhalation, ingestion or the skin. Yellow staining is typical in toxications via skin contact. The main toxic effects of DNOC derivatives are due to an increase in cellular metabolism. It acts directly on metabolism by inducing cellular oxidation and inhibiting phosphorylation, leading to the uncoupling of oxidative phosphorylation. Cardiovascular effects appear to be secondary to cellular anoxia. We report here two consecutive patients admitted to the emergency department with an initial diagnosis of toxic exposure to DNOC. Further examination revealed that toxic exposure led to simultaneous acute coronary syndrome.

 

Nitrophenols are common components of industrial effluents and have been detected in urban and agricultural waste. Dinitro-ortho-cresol (DNOC) can easily enter the body through inhalation, ingestion or the skin. Yellow staining is typical in toxications via skin contact. The main toxic effects of DNOC derivatives are due to an increase in cellular metabolism. It acts directly on metabolism by inducing cellular oxidation and inhibiting phosphorylation, leading to the uncoupling of oxidative phosphorylation. Cardiovascular effects appear to be secondary to cellular anoxia. We report here two consecutive patients admitted to the emergency department with an initial diagnosis of toxic exposure to DNOC. Further examination revealed that toxic exposure led to simultaneous acute coronary syndrome.

Makale detayları

Dinitro-Ortho-Cresol Maruziyeti Sonrasında Akut Koroner Sendrom GelişenArdışık İki Hasta

Yazarlar: Ahmet Oğuz BAKTIR | Hayrettin SAĞLAM | Bahadır ŞARLI | Hüseyin ARINÇ | Yasemin DOĞAN | Hüseyin KATLANDUR

Yayıncı: Acil Tıp Uzmanları Derneği

Dergi: Journal of Emergency Medicine Case Reports 2013 Vol.4 Issue 4, pp.147-150

Belge Tipi: Makale

Yayın Tarihi: 9/2013

Belge Dili: Türkçe

Document ID (Org No.): 2000505059

Sıklık: Aylık

eISSN: 2149-9934

Sayı

Yazarlar:

Ahmet Oğuz BAKTIR | Hayrettin SAĞLAM | Bahadır ŞARLI | Hüseyin ARINÇ | Yasemin DOĞAN | Hüseyin KATLANDUR

Yayıncı:

Acil Tıp Uzmanları Derneği

Dergi:

Journal of Emergency Medicine Case Reports 2013 Vol.4 Issue 4, pp.147-150

Belge Tipi:

Makale

Yayın Tarihi:

9/2013

Belge Dili:

Türkçe

Document ID (Org No.):

2000505059

Sıklık:

Aylık

eISSN:

2149-9934