Phytochemistry, Cytotoxicity, and Antibacterial Activity of Almaciga (Agathis philippinensis) Aqueous Resin Extract

N.A.

Makale detayları

Phytochemistry, Cytotoxicity, and Antibacterial Activity of Almaciga (Agathis philippinensis) Aqueous Resin Extract

Yazarlar:

N.A.

Yayıncı:

Bursa Uludağ University

Ana Başlıklar:

Agricultural Biotechnology (Other)

Dergi:

Journal of Biological and Environmental Sciences Vol.19 Issue 55, pp.1-9

Belge Tipi:

Makale

Yayın Tarihi:

1/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001345427

pISSN:

1307-9530

Anahtar kelimeler:

Özet:

 This study investigated the phytochemistry, cytotoxicity, and antibacterial activity of almaciga Agathis philippinensis resin sourced from Governor Generoso, Davao Oriental, using water as the extracting solvent. Phytochemical screening employed various tests, including Borntragers test for anthraquinones, a coumarin test, the Alkaline Reagent test for flavonoids, the Froth test for saponins, and the Salkowski test for terpenoids. The cytotoxic activity was assessed using the brine shrimp lethality test, while the antibacterial activity was evaluated through the disc diffusion method. The study found the presence of terpenoids and saponins in the aqueous extract of almaciga A. philippinensis resin. The cytotoxicity results indicated a high mortality rate of 85 at a concentration of 1000 μgml, with an LC50 value of 401.65 μgml, which is classified as toxic according to Meyers Toxicity Index. Furthermore, the concentrated crude extract demonstrated significant inhibitory effects against Staphylococcus aureus, with an average zone of inhibition measuring 21.0 mm. These findings underscore the pharmacological potential of almaciga resin, though further investigation is encouraged to validate the results.

 This study investigated the phytochemistry, cytotoxicity, and antibacterial activity of almaciga Agathis philippinensis resin sourced from Governor Generoso, Davao Oriental, using water as the extracting solvent. Phytochemical screening employed various tests, including Borntragers test for anthraquinones, a coumarin test, the Alkaline Reagent test for flavonoids, the Froth test for saponins, and the Salkowski test for terpenoids. The cytotoxic activity was assessed using the brine shrimp lethality test, while the antibacterial activity was evaluated through the disc diffusion method. The study found the presence of terpenoids and saponins in the aqueous extract of almaciga A. philippinensis resin. The cytotoxicity results indicated a high mortality rate of 85 at a concentration of 1000 μgml, with an LC50 value of 401.65 μgml, which is classified as toxic according to Meyers Toxicity Index. Furthermore, the concentrated crude extract demonstrated significant inhibitory effects against Staphylococcus aureus, with an average zone of inhibition measuring 21.0 mm. These findings underscore the pharmacological potential of almaciga resin, though further investigation is encouraged to validate the results.

 This study investigated the phytochemistry, cytotoxicity, and antibacterial activity of almaciga Agathis philippinensis resin sourced from Governor Generoso, Davao Oriental, using water as the extracting solvent. Phytochemical screening employed various tests, including Borntragers test for anthraquinones, a coumarin test, the Alkaline Reagent test for flavonoids, the Froth test for saponins, and the Salkowski test for terpenoids. The cytotoxic activity was assessed using the brine shrimp lethality test, while the antibacterial activity was evaluated through the disc diffusion method. The study found the presence of terpenoids and saponins in the aqueous extract of almaciga A. philippinensis resin. The cytotoxicity results indicated a high mortality rate of 85 at a concentration of 1000 μgml, with an LC50 value of 401.65 μgml, which is classified as toxic according to Meyers Toxicity Index. Furthermore, the concentrated crude extract demonstrated significant inhibitory effects against Staphylococcus aureus, with an average zone of inhibition measuring 21.0 mm. These findings underscore the pharmacological potential of almaciga resin, though further investigation is encouraged to validate the results.

 This study investigated the phytochemistry, cytotoxicity, and antibacterial activity of almaciga Agathis philippinensis resin sourced from Governor Generoso, Davao Oriental, using water as the extracting solvent. Phytochemical screening employed various tests, including Borntragers test for anthraquinones, a coumarin test, the Alkaline Reagent test for flavonoids, the Froth test for saponins, and the Salkowski test for terpenoids. The cytotoxic activity was assessed using the brine shrimp lethality test, while the antibacterial activity was evaluated through the disc diffusion method. The study found the presence of terpenoids and saponins in the aqueous extract of almaciga A. philippinensis resin. The cytotoxicity results indicated a high mortality rate of 85 at a concentration of 1000 μgml, with an LC50 value of 401.65 μgml, which is classified as toxic according to Meyers Toxicity Index. Furthermore, the concentrated crude extract demonstrated significant inhibitory effects against Staphylococcus aureus, with an average zone of inhibition measuring 21.0 mm. These findings underscore the pharmacological potential of almaciga resin, though further investigation is encouraged to validate the results.

Makale detayları

Phytochemistry, Cytotoxicity, and Antibacterial Activity of Almaciga (Agathis philippinensis) Aqueous Resin Extract

Yazarlar:

N.A.

Yayıncı:

Bursa Uludağ University

Ana Başlıklar:

Agricultural Biotechnology (Other)

Dergi:

Journal of Biological and Environmental Sciences Vol.19 Issue 55, pp.1-9

Belge Tipi:

Makale

Yayın Tarihi:

1/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001345427

pISSN:

1307-9530

Agathis philippinensis

almaciga

antibacterial activity

aqueous resin extract

cytotoxicity

Staphylococcus aureus

Sayı

Makale detayları

Phytochemistry, Cytotoxicity, and Antibacterial Activity of Almaciga (Agathis philippinensis) Aqueous Resin Extract

Yazarlar: N.A.

Yayıncı: Bursa Uludağ University

Ana Başlıklar: Agricultural Biotechnology (Other)

Dergi: Journal of Biological and Environmental Sciences Vol.19 Issue 55, pp.1-9

Belge Tipi: Makale

Yayın Tarihi: 1/2025

Belge Dili: İngilizce

Document ID (Org No.): 2001345427

pISSN: 1307-9530

Agathis philippinensis

almaciga

antibacterial activity

aqueous resin extract

cytotoxicity

Staphylococcus aureus

Sayı

Yazarlar:

N.A.

Yayıncı:

Bursa Uludağ University

Ana Başlıklar:

Agricultural Biotechnology (Other)

Dergi:

Journal of Biological and Environmental Sciences Vol.19 Issue 55, pp.1-9

Belge Tipi:

Makale

Yayın Tarihi:

1/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001345427

pISSN:

1307-9530