The quantification for the treatment response evaluation of Metastatic Gastroenteropancreatic Neuroendocrine Tumors in Ga-68 DOTATATE PET/CT

Zehra Pınar Koç; Pınar Pelin Özcan; Tuba Kara

Makale detayları

The quantification for the treatment response evaluation of Metastatic Gastroenteropancreatic Neuroendocrine Tumors in Ga-68 DOTATATE PET/CT

Yazarlar:

Zehra Pınar Koç | Pınar Pelin Özcan | Tuba Kara

Yayıncı:

Mersin University

Ana Başlıklar:

Gastroenterology and Hepatology | Nuclear Medicine

Dergi:

Molecular Oncologic Imaging Vol.4 Issue 2, pp.17-23

Belge Tipi:

Makale

Yayın Tarihi:

6/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001326704

pISSN:

2791-965X

Anahtar kelimeler:

Özet:

 Aim: The treatment response evaluation by means of Ga-68 DOTATATE PETCT in Metastatic Gastroenteropancreatic Neuroendocrine Tumors GEPNETs needs careful attention due to the subtle changes that might affect decision. The aim of this study is to analyze a new modified method in quantification of the Ga-68 DOTATATE PETCT in treatment response evaluation of GEP-NETs. Materials and Methods: 37 patients with diagnosis of metastatik GEP-NET were included in the study. Comparative evaluation of Ga-68 DOTATATE PETCT images before and after treatment were performed. Quantitative analysis as well as visual interpretation results were compared with oncology follow up. The patients were divided according to oncology follow up results as responders and nonresponders. Results: The comparative analysis results showed that the difference between mean SUVmax and index values after and before the treatment were not significant for primary lesions. However both the index values were significantly different between groups in metastatic lesions. Conclusion: The SUVmax levels of the metastatic lesions could be considered for determination of treatment response and quantification for the treatment response might be indicated in special cases.

 Aim: The treatment response evaluation by means of Ga-68 DOTATATE PETCT in Metastatic Gastroenteropancreatic Neuroendocrine Tumors GEPNETs needs careful attention due to the subtle changes that might affect decision. The aim of this study is to analyze a new modified method in quantification of the Ga-68 DOTATATE PETCT in treatment response evaluation of GEP-NETs. Materials and Methods: 37 patients with diagnosis of metastatik GEP-NET were included in the study. Comparative evaluation of Ga-68 DOTATATE PETCT images before and after treatment were performed. Quantitative analysis as well as visual interpretation results were compared with oncology follow up. The patients were divided according to oncology follow up results as responders and nonresponders. Results: The comparative analysis results showed that the difference between mean SUVmax and index values after and before the treatment were not significant for primary lesions. However both the index values were significantly different between groups in metastatic lesions. Conclusion: The SUVmax levels of the metastatic lesions could be considered for determination of treatment response and quantification for the treatment response might be indicated in special cases.

 Aim: The treatment response evaluation by means of Ga-68 DOTATATE PETCT in Metastatic Gastroenteropancreatic Neuroendocrine Tumors GEPNETs needs careful attention due to the subtle changes that might affect decision. The aim of this study is to analyze a new modified method in quantification of the Ga-68 DOTATATE PETCT in treatment response evaluation of GEP-NETs. Materials and Methods: 37 patients with diagnosis of metastatik GEP-NET were included in the study. Comparative evaluation of Ga-68 DOTATATE PETCT images before and after treatment were performed. Quantitative analysis as well as visual interpretation results were compared with oncology follow up. The patients were divided according to oncology follow up results as responders and nonresponders. Results: The comparative analysis results showed that the difference between mean SUVmax and index values after and before the treatment were not significant for primary lesions. However both the index values were significantly different between groups in metastatic lesions. Conclusion: The SUVmax levels of the metastatic lesions could be considered for determination of treatment response and quantification for the treatment response might be indicated in special cases.

 Aim: The treatment response evaluation by means of Ga-68 DOTATATE PETCT in Metastatic Gastroenteropancreatic Neuroendocrine Tumors GEPNETs needs careful attention due to the subtle changes that might affect decision. The aim of this study is to analyze a new modified method in quantification of the Ga-68 DOTATATE PETCT in treatment response evaluation of GEP-NETs. Materials and Methods: 37 patients with diagnosis of metastatik GEP-NET were included in the study. Comparative evaluation of Ga-68 DOTATATE PETCT images before and after treatment were performed. Quantitative analysis as well as visual interpretation results were compared with oncology follow up. The patients were divided according to oncology follow up results as responders and nonresponders. Results: The comparative analysis results showed that the difference between mean SUVmax and index values after and before the treatment were not significant for primary lesions. However both the index values were significantly different between groups in metastatic lesions. Conclusion: The SUVmax levels of the metastatic lesions could be considered for determination of treatment response and quantification for the treatment response might be indicated in special cases.

Makale detayları

The quantification for the treatment response evaluation of Metastatic Gastroenteropancreatic Neuroendocrine Tumors in Ga-68 DOTATATE PET/CT

Yazarlar:

Zehra Pınar Koç | Pınar Pelin Özcan | Tuba Kara

Yayıncı:

Mersin University

Ana Başlıklar:

Gastroenterology and Hepatology | Nuclear Medicine

Dergi:

Molecular Oncologic Imaging Vol.4 Issue 2, pp.17-23

Belge Tipi:

Makale

Yayın Tarihi:

6/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001326704

pISSN:

2791-965X

Ga-68 DOTATATE

malignancy

positron emission tomography

fluorodeoxyglucose

Sayı

Makale detayları

The quantification for the treatment response evaluation of Metastatic Gastroenteropancreatic Neuroendocrine Tumors in Ga-68 DOTATATE PET/CT

Yazarlar: Zehra Pınar Koç | Pınar Pelin Özcan | Tuba Kara

Yayıncı: Mersin University

Ana Başlıklar: Gastroenterology and Hepatology | Nuclear Medicine

Dergi: Molecular Oncologic Imaging Vol.4 Issue 2, pp.17-23

Belge Tipi: Makale

Yayın Tarihi: 6/2024

Belge Dili: İngilizce

Document ID (Org No.): 2001326704

pISSN: 2791-965X

Ga-68 DOTATATE

malignancy

positron emission tomography

fluorodeoxyglucose

Sayı

Yazarlar:

Zehra Pınar Koç | Pınar Pelin Özcan | Tuba Kara

Yayıncı:

Mersin University

Ana Başlıklar:

Gastroenterology and Hepatology | Nuclear Medicine

Dergi:

Molecular Oncologic Imaging Vol.4 Issue 2, pp.17-23

Belge Tipi:

Makale

Yayın Tarihi:

6/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001326704

pISSN:

2791-965X