Assessment of vitamin D deficiency and hyperparathyroidism in metabolically healthy and unhealthy obese patients

Nergis Akbaş; Emin Akbaş

Makale detayları

Assessment of vitamin D deficiency and hyperparathyroidism in metabolically healthy and unhealthy obese patients

Yazarlar:

Nergis Akbaş | Emin Akbaş

Yayıncı:

MediHealth Academy Yayıncılık

Ana Başlıklar:

İç Hastalıkları

Dergi:

Journal of Health Sciences and Medicine Vol.6 Issue 5, pp.968-973

Belge Tipi:

Makale

Yayın Tarihi:

9/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001299329

pISSN:

2636-8579

Anahtar kelimeler:

Özet:

 Aims: This study aimed to compare the levels of vitamin D in metabolically healthy MHO and metabolically unhealthy obese MUO individuals and determine if there are differences between these two groups concerning vitamin D deficiency and hyperparathyroidism. Methods: A total of 263 obese female patients were included in the study and divided into two groups based on metabolic syndrome diagnostic criteria. Biochemical and anthropometric data obtained after a 12-hour fasting period were analyzed. Results: Among the patients, the average 25-OH vitamin D level was 10.96.5 ngml. A total of 242 patients 92 had vitamin D deficiency, and 132 patients 50.2 were diagnosed with hyperparathyroidism. Significant differences were found in vitamin D p0.003 and uric acid p0.001 levels between the MHO and MUO groups. Additionally, the groups with vitamin D deficiency showed significantly different glucose p0.026 and homeostatic model assessment for insulin resistance p0.042 values. Patients with hyperparathyroidism had higher waist circumference p0.001, waist-to-hip ratio p0.018, BMI p0.006, and systolic p0.001 and diastolic p0.001 blood pressure values compared to those with normal parathyroid hormone levels. Conclusion: The study emphasizes the importance of monitoring vitamin D deficiency and hyperparathyroidism in obese patients, as these conditions are more prevalent in this population and might be associated with metabolic syndrome parameters, increasing cardiometabolic risk.

 Aims: This study aimed to compare the levels of vitamin D in metabolically healthy MHO and metabolically unhealthy obese MUO individuals and determine if there are differences between these two groups concerning vitamin D deficiency and hyperparathyroidism. Methods: A total of 263 obese female patients were included in the study and divided into two groups based on metabolic syndrome diagnostic criteria. Biochemical and anthropometric data obtained after a 12-hour fasting period were analyzed. Results: Among the patients, the average 25-OH vitamin D level was 10.96.5 ngml. A total of 242 patients 92 had vitamin D deficiency, and 132 patients 50.2 were diagnosed with hyperparathyroidism. Significant differences were found in vitamin D p0.003 and uric acid p0.001 levels between the MHO and MUO groups. Additionally, the groups with vitamin D deficiency showed significantly different glucose p0.026 and homeostatic model assessment for insulin resistance p0.042 values. Patients with hyperparathyroidism had higher waist circumference p0.001, waist-to-hip ratio p0.018, BMI p0.006, and systolic p0.001 and diastolic p0.001 blood pressure values compared to those with normal parathyroid hormone levels. Conclusion: The study emphasizes the importance of monitoring vitamin D deficiency and hyperparathyroidism in obese patients, as these conditions are more prevalent in this population and might be associated with metabolic syndrome parameters, increasing cardiometabolic risk.

 Aims: This study aimed to compare the levels of vitamin D in metabolically healthy MHO and metabolically unhealthy obese MUO individuals and determine if there are differences between these two groups concerning vitamin D deficiency and hyperparathyroidism. Methods: A total of 263 obese female patients were included in the study and divided into two groups based on metabolic syndrome diagnostic criteria. Biochemical and anthropometric data obtained after a 12-hour fasting period were analyzed. Results: Among the patients, the average 25-OH vitamin D level was 10.96.5 ngml. A total of 242 patients 92 had vitamin D deficiency, and 132 patients 50.2 were diagnosed with hyperparathyroidism. Significant differences were found in vitamin D p0.003 and uric acid p0.001 levels between the MHO and MUO groups. Additionally, the groups with vitamin D deficiency showed significantly different glucose p0.026 and homeostatic model assessment for insulin resistance p0.042 values. Patients with hyperparathyroidism had higher waist circumference p0.001, waist-to-hip ratio p0.018, BMI p0.006, and systolic p0.001 and diastolic p0.001 blood pressure values compared to those with normal parathyroid hormone levels. Conclusion: The study emphasizes the importance of monitoring vitamin D deficiency and hyperparathyroidism in obese patients, as these conditions are more prevalent in this population and might be associated with metabolic syndrome parameters, increasing cardiometabolic risk.

 Aims: This study aimed to compare the levels of vitamin D in metabolically healthy MHO and metabolically unhealthy obese MUO individuals and determine if there are differences between these two groups concerning vitamin D deficiency and hyperparathyroidism. Methods: A total of 263 obese female patients were included in the study and divided into two groups based on metabolic syndrome diagnostic criteria. Biochemical and anthropometric data obtained after a 12-hour fasting period were analyzed. Results: Among the patients, the average 25-OH vitamin D level was 10.96.5 ngml. A total of 242 patients 92 had vitamin D deficiency, and 132 patients 50.2 were diagnosed with hyperparathyroidism. Significant differences were found in vitamin D p0.003 and uric acid p0.001 levels between the MHO and MUO groups. Additionally, the groups with vitamin D deficiency showed significantly different glucose p0.026 and homeostatic model assessment for insulin resistance p0.042 values. Patients with hyperparathyroidism had higher waist circumference p0.001, waist-to-hip ratio p0.018, BMI p0.006, and systolic p0.001 and diastolic p0.001 blood pressure values compared to those with normal parathyroid hormone levels. Conclusion: The study emphasizes the importance of monitoring vitamin D deficiency and hyperparathyroidism in obese patients, as these conditions are more prevalent in this population and might be associated with metabolic syndrome parameters, increasing cardiometabolic risk.

Makale detayları

Assessment of vitamin D deficiency and hyperparathyroidism in metabolically healthy and unhealthy obese patients

Yazarlar:

Nergis Akbaş | Emin Akbaş

Yayıncı:

MediHealth Academy Yayıncılık

Ana Başlıklar:

İç Hastalıkları

Dergi:

Journal of Health Sciences and Medicine Vol.6 Issue 5, pp.968-973

Belge Tipi:

Makale

Yayın Tarihi:

9/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001299329

pISSN:

2636-8579

Vitamin D deficiency

obesity

hyperparathyroidism

metabolic syndrome

cardiovascular disease

Sayı

Makale detayları

Assessment of vitamin D deficiency and hyperparathyroidism in metabolically healthy and unhealthy obese patients

Yazarlar: Nergis Akbaş | Emin Akbaş

Yayıncı: MediHealth Academy Yayıncılık

Ana Başlıklar: İç Hastalıkları

Dergi: Journal of Health Sciences and Medicine Vol.6 Issue 5, pp.968-973

Belge Tipi: Makale

Yayın Tarihi: 9/2023

Belge Dili: İngilizce

Document ID (Org No.): 2001299329

pISSN: 2636-8579

Vitamin D deficiency

obesity

hyperparathyroidism

metabolic syndrome

cardiovascular disease

Sayı

Yazarlar:

Nergis Akbaş | Emin Akbaş

Yayıncı:

MediHealth Academy Yayıncılık

Ana Başlıklar:

İç Hastalıkları

Dergi:

Journal of Health Sciences and Medicine Vol.6 Issue 5, pp.968-973

Belge Tipi:

Makale

Yayın Tarihi:

9/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001299329

pISSN:

2636-8579