Mucormycosis: a 10-year experience at a tertiary care center in Turkey

Süheyla KÖMÜR; Ayşe Seza İNAL; Behice KURTARAN; Aslihan ULU; Aysun UĞUZ; Hasan Salih Zeki AKSU; Yeşim TAŞOVA

Makale detayları

Mucormycosis: a 10-year experience at a tertiary care center in Turkey

Yazarlar:

Süheyla KÖMÜR | Ayşe Seza İNAL | Behice KURTARAN | Aslihan ULU | Aysun UĞUZ | Hasan Salih Zeki AKSU | Yeşim TAŞOVA

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2016 Vol.46 Issue 1, pp.58-62

Belge Tipi:

Makale

Yayın Tarihi:

1/2016

Belge Dili:

Türkçe

Document ID (Org No.):

2000752295

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144

Özet:

 

Background/aim: Mucormycosis is a rare invasive fungal infection most commonly encountered in the immunocompromised host. We analyzed 51 adult patients treated for mucormycosis between 2003 and 2013 and recorded at a tertiary university hospital in Turkey.  Materials and methods: We examined the following data for all patients: age, sex, predisposing disease, symptoms, treatment, surgical procedure, concomitant infections, intensive care requirement, and outcomes.  Results: During the study period 51 cases of mucormycosis were documented; 54.9% of the patients were female. The mean age was 44.2 ± 18.2 years. Rhinocerebral presentation was reported in 94.1% of patients. Almost all patients (88.2%) had at least one risk factor. The common predisposing factors were hematologic malignancies (52.9%), diabetes mellitus (25.5%), and solid malignancies (5.8%). The most common initial symptoms were fever, cellulitis, and facial pain. The primary medication used was liposomal amphotericin B or conventional amphotericin B. Surgery was performed in 94.1% of patients. Mortality was 52.9%.   Conclusion: Our study revealed that mucormycosis continues to be a mortal disease in about half of the cases. Our findings indicate that treatment with L-AMB is associated with a favorable response. Also, in the case of facial pain, the low mortality rate may indicate the importance of early diagnosis.

Makale detayları

Mucormycosis: a 10-year experience at a tertiary care center in Turkey

Yazarlar: Süheyla KÖMÜR | Ayşe Seza İNAL | Behice KURTARAN | Aslihan ULU | Aysun UĞUZ | Hasan Salih Zeki AKSU | Yeşim TAŞOVA

Yayıncı: TUBITAK

Dergi: Turkish Journal of Medical Sciences 2016 Vol.46 Issue 1, pp.58-62

Belge Tipi: Makale

Yayın Tarihi: 1/2016

Belge Dili: Türkçe

Document ID (Org No.): 2000752295

Sıklık: İki Aylık

eISSN: 1303-6165

pISSN: 1300-0144

Sayı

Yazarlar:

Süheyla KÖMÜR | Ayşe Seza İNAL | Behice KURTARAN | Aslihan ULU | Aysun UĞUZ | Hasan Salih Zeki AKSU | Yeşim TAŞOVA

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2016 Vol.46 Issue 1, pp.58-62

Belge Tipi:

Makale

Yayın Tarihi:

1/2016

Belge Dili:

Türkçe

Document ID (Org No.):

2000752295

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144