Co(III) catalysed asymmetric ring-opening of epichlorohydrin by salicylaldehyde derivatives: reversal of enantioselectivity and rate acceleration on addition of AlCl3

Leman KARADENİZ; Gamze KOZ; Kadriye AYDIN; Stephen T. ASTLEY

Makale detayları

Co(III) catalysed asymmetric ring-opening of epichlorohydrin by salicylaldehyde derivatives: reversal of enantioselectivity and rate acceleration on addition of AlCl3

Yazarlar:

Leman KARADENİZ | Gamze KOZ | Kadriye AYDIN | Stephen T. ASTLEY

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Chemistry 2010 Vol.34 Issue 5, pp.711-718

Belge Tipi:

Makale

Yayın Tarihi:

4/2010

Belge Dili:

Türkçe

Document ID (Org No.):

2000727973

Sıklık:

İki Aylık

eISSN:

1303-6130

pISSN:

1300-0527

Özet:

 

Using asymmetric Cobalt(III) salen catalysts, the  ring-opening of epichlorohydrin by 2,3-dihydroxybenzal- dehyde and  2,4- dihydroxybenzaldehyde was found to occur at the phenolic groups  most distant from the aldehydic group.  Switching catalysts afforded a reversal in enantioselectivity.  For 2,3-dihydroxybenzaldehyde and  salicylaldehyde, addition of AlCl3 to the reaction mixture led to an  increase in reaction rate without any decrease in product  enantiopurity.

 

Using asymmetric Cobalt(III) salen catalysts, the  ring-opening of epichlorohydrin by 2,3-dihydroxybenzal- dehyde and  2,4- dihydroxybenzaldehyde was found to occur at the phenolic groups  most distant from the aldehydic group.  Switching catalysts afforded a reversal in enantioselectivity.  For 2,3-dihydroxybenzaldehyde and  salicylaldehyde, addition of AlCl3 to the reaction mixture led to an  increase in reaction rate without any decrease in product  enantiopurity.

Makale detayları

Co(III) catalysed asymmetric ring-opening of epichlorohydrin by salicylaldehyde derivatives: reversal of enantioselectivity and rate acceleration on addition of AlCl3

Yazarlar: Leman KARADENİZ | Gamze KOZ | Kadriye AYDIN | Stephen T. ASTLEY

Yayıncı: TUBITAK

Dergi: Turkish Journal of Chemistry 2010 Vol.34 Issue 5, pp.711-718

Belge Tipi: Makale

Yayın Tarihi: 4/2010

Belge Dili: Türkçe

Document ID (Org No.): 2000727973

Sıklık: İki Aylık

eISSN: 1303-6130

pISSN: 1300-0527

Sayı

Yazarlar:

Leman KARADENİZ | Gamze KOZ | Kadriye AYDIN | Stephen T. ASTLEY

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Chemistry 2010 Vol.34 Issue 5, pp.711-718

Belge Tipi:

Makale

Yayın Tarihi:

4/2010

Belge Dili:

Türkçe

Document ID (Org No.):

2000727973

Sıklık:

İki Aylık

eISSN:

1303-6130

pISSN:

1300-0527