Prolidase Enzyme Activity in Endometrial Polyps and Its Relationship with Oxidative Stress

Farida Hajıbayli; Mehmet Ferdi Kıncı; Burak Sezgin; Burcu Kasap; Ercan Saruhan; Ahmet Akın Sivaslıoğlu

Makale detayları

Prolidase Enzyme Activity in Endometrial Polyps and Its Relationship with Oxidative Stress

Yazarlar:

Farida Hajıbayli | Mehmet Ferdi Kıncı | Burak Sezgin | Burcu Kasap | Ercan Saruhan | Ahmet Akın Sivaslıoğlu

Yayıncı:

Mugla Sitki Kocman University

Ana Başlıklar:

Klinik Tıp Bilimleri (Diğer)

Dergi:

Muğla Sıtkı Koçman Üniversitesi Tıp Dergisi Vol.11 Issue 1, pp.20-24

Belge Tipi:

Makale

Yayın Tarihi:

4/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001316050

pISSN:

2148-8118

Anahtar kelimeler:

Özet:

 Endometrial polyp EP is a condition that is often encountered in obstetrics and gynecology clinic practices. In our study, we aimed to reveal the relationship between prolidase enzyme activity PEA and Oxidative Stress OS in patients with endometrial polyps. Thirty-five patients who were histopathologically diagnosed with EP and 35 patients with abnormal uterine bleeding AUB without pathology as a result of endometrial sampling were included in the control group. Serum TOS, OSI, tissue PEA, and endometrial thickness values were found to be statistically significantly higher in the EP group compared to the control group. We believe that our study, when supported by studies with larger patient groups, may be a useful marker for a more detailed understanding of the pathogenesis and clinical follow-up of patients.

 Endometrial polyp EP is a condition that is often encountered in obstetrics and gynecology clinic practices. In our study, we aimed to reveal the relationship between prolidase enzyme activity PEA and Oxidative Stress OS in patients with endometrial polyps. Thirty-five patients who were histopathologically diagnosed with EP and 35 patients with abnormal uterine bleeding AUB without pathology as a result of endometrial sampling were included in the control group. Serum TOS, OSI, tissue PEA, and endometrial thickness values were found to be statistically significantly higher in the EP group compared to the control group. We believe that our study, when supported by studies with larger patient groups, may be a useful marker for a more detailed understanding of the pathogenesis and clinical follow-up of patients.

 Endometrial polyp EP is a condition that is often encountered in obstetrics and gynecology clinic practices. In our study, we aimed to reveal the relationship between prolidase enzyme activity PEA and Oxidative Stress OS in patients with endometrial polyps. Thirty-five patients who were histopathologically diagnosed with EP and 35 patients with abnormal uterine bleeding AUB without pathology as a result of endometrial sampling were included in the control group. Serum TOS, OSI, tissue PEA, and endometrial thickness values were found to be statistically significantly higher in the EP group compared to the control group. We believe that our study, when supported by studies with larger patient groups, may be a useful marker for a more detailed understanding of the pathogenesis and clinical follow-up of patients.

 Endometrial polip EP kadın hastalıkları ve doğum kliniği pratiğinde sıklıkla karşılaşılan bir durumdur. Biz çalışmamızda endometrial polip tanısı olan hastaların prolidaz enzim aktivitesi ve oksidatif stres OS ile ilişkisini ortaya çıkarmayı amaçladık. Araştırmaya dahil edilme kriterlerini karşılayan histopatolojik olarak EP tanısı konan 35 hasta ile endometrial örnekleme sonucunda patoloji tespit edilmeyen 35 anormal uterin kanaması AUK olan kontrol grubu hastası dahil edilmiştir. EP ve kontrol grupları arasında TAS, TOS, OSI, prolidaz ve endometrium kalınlığı değerleri karşılaştırıldığında EP grubunda, kontrol grubuna göre TOS, OSI, prolidaz ve endometrial kalınlık değerleri istatistiksel olarak anlamlı düzeyde yüksek bulunmuştur. Çalışmamız, daha geniş hasta grupları ile yapılan çalışmalarla desteklendiğinde patogenezin daha ayrıntılı anlaşılması ve klinik olarak hasta takibinde yararlı bir belirteç olabileceği görüşündeyiz.

Makale detayları

Prolidase Enzyme Activity in Endometrial Polyps and Its Relationship with Oxidative Stress

Yazarlar:

Farida Hajıbayli | Mehmet Ferdi Kıncı | Burak Sezgin | Burcu Kasap | Ercan Saruhan | Ahmet Akın Sivaslıoğlu

Yayıncı:

Mugla Sitki Kocman University

Ana Başlıklar:

Klinik Tıp Bilimleri (Diğer)

Dergi:

Muğla Sıtkı Koçman Üniversitesi Tıp Dergisi Vol.11 Issue 1, pp.20-24

Belge Tipi:

Makale

Yayın Tarihi:

4/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001316050

pISSN:

2148-8118

Endometrial Polyp

Oxidative Stress

Prolidase Enzyme ActivityEndometrial Polip

Oksidatif Stress

Prolidaz Enzim Aktivitesi

Sayı

Makale detayları

Prolidase Enzyme Activity in Endometrial Polyps and Its Relationship with Oxidative Stress

Yazarlar: Farida Hajıbayli | Mehmet Ferdi Kıncı | Burak Sezgin | Burcu Kasap | Ercan Saruhan | Ahmet Akın Sivaslıoğlu

Yayıncı: Mugla Sitki Kocman University

Ana Başlıklar: Klinik Tıp Bilimleri (Diğer)

Dergi: Muğla Sıtkı Koçman Üniversitesi Tıp Dergisi Vol.11 Issue 1, pp.20-24

Belge Tipi: Makale

Yayın Tarihi: 4/2024

Belge Dili: İngilizce

Document ID (Org No.): 2001316050

pISSN: 2148-8118

Endometrial Polyp

Oxidative Stress

Prolidase Enzyme ActivityEndometrial Polip

Oksidatif Stress

Prolidaz Enzim Aktivitesi

Sayı

Yazarlar:

Farida Hajıbayli | Mehmet Ferdi Kıncı | Burak Sezgin | Burcu Kasap | Ercan Saruhan | Ahmet Akın Sivaslıoğlu

Yayıncı:

Mugla Sitki Kocman University

Ana Başlıklar:

Klinik Tıp Bilimleri (Diğer)

Dergi:

Muğla Sıtkı Koçman Üniversitesi Tıp Dergisi Vol.11 Issue 1, pp.20-24

Belge Tipi:

Makale

Yayın Tarihi:

4/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001316050

pISSN:

2148-8118