The Effect of Fish Oil on Liver and Plasma MDA and Antioxidant Status of Rats

Nuriye METE

Makale detayları

The Effect of Fish Oil on Liver and Plasma MDA and Antioxidant Status of Rats

Yazarlar:

Nuriye METE

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 1999 Vol.29 Issue 1, pp.1-6

Belge Tipi:

Makale

Yayın Tarihi:

12/1998

Belge Dili:

Türkçe

Document ID (Org No.):

2000758107

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144

Anahtar kelimeler:

Özet:

 

The question how fish oil (FO) and  soybean oil (SO) change the state of  antioxidant and the lipid peroxidation in liver  and plasma of rats and the protective role of  vitamin E were investigated. Six-week-old  forty male Sprague-Dawley rats were divided  into five groups. One of the groups fed a  control diet, another one fed SO, while the  other three groups fed FO diet at the level of  10% Vitamin E supplementation was  maintained to three different levels 3, 50,  150 IU/per kg diet in the FO diets and 3 IU  vitamin E per kg of the SO diet. At the end of  tenth week, blood was drawn under ether  anesthesia and finally plasma and red blood  cell samples were separated. Liver tissues  were washed by 0.9% NaCl, then dried by a  filter paper and stored at -60oC. The  malondialdehyde (MDA) amount as an  indicator of lipid peroxidation was not  significantly affected in the SO group, while it  was found increased both in serum and liver  tissue in the FO group with vitamin E  supplementation of 3 IU/kg diet (P.

 

The question how fish oil (FO) and  soybean oil (SO) change the state of  antioxidant and the lipid peroxidation in liver  and plasma of rats and the protective role of  vitamin E were investigated. Six-week-old  forty male Sprague-Dawley rats were divided  into five groups. One of the groups fed a  control diet, another one fed SO, while the  other three groups fed FO diet at the level of  10% Vitamin E supplementation was  maintained to three different levels 3, 50,  150 IU/per kg diet in the FO diets and 3 IU  vitamin E per kg of the SO diet. At the end of  tenth week, blood was drawn under ether  anesthesia and finally plasma and red blood  cell samples were separated. Liver tissues  were washed by 0.9% NaCl, then dried by a  filter paper and stored at -60oC. The  malondialdehyde (MDA) amount as an  indicator of lipid peroxidation was not  significantly affected in the SO group, while it  was found increased both in serum and liver  tissue in the FO group with vitamin E  supplementation of 3 IU/kg diet (P.

Makale detayları

The Effect of Fish Oil on Liver and Plasma MDA and Antioxidant Status of Rats

Yazarlar:

Nuriye METE

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 1999 Vol.29 Issue 1, pp.1-6

Belge Tipi:

Makale

Yayın Tarihi:

12/1998

Belge Dili:

Türkçe

Document ID (Org No.):

2000758107

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144

Turk J Med Sci 1999; 29(1): 1-6. Full text: pdf Other articles published in the same issue: Turk J Med Sci

vol.29

iss.1.

Sayı

Makale detayları

The Effect of Fish Oil on Liver and Plasma MDA and Antioxidant Status of Rats

Yazarlar: Nuriye METE

Yayıncı: TUBITAK

Dergi: Turkish Journal of Medical Sciences 1999 Vol.29 Issue 1, pp.1-6

Belge Tipi: Makale

Yayın Tarihi: 12/1998

Belge Dili: Türkçe

Document ID (Org No.): 2000758107

Sıklık: İki Aylık

eISSN: 1303-6165

pISSN: 1300-0144

Turk J Med Sci 1999; 29(1): 1-6. Full text: pdf Other articles published in the same issue: Turk J Med Sci

vol.29

iss.1.

Sayı

Yazarlar:

Nuriye METE

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 1999 Vol.29 Issue 1, pp.1-6

Belge Tipi:

Makale

Yayın Tarihi:

12/1998

Belge Dili:

Türkçe

Document ID (Org No.):

2000758107

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144