Biocompatibility of different resin composites after polymerization with two light curing units: an immunohistochemical study

İrem İpek; Murat Ünal; Tülay Koç

Makale detayları

Biocompatibility of different resin composites after polymerization with two light curing units: an immunohistochemical study

Yazarlar:

İrem İpek | Murat Ünal | Tülay Koç

Yayıncı:

Istanbul University

Ana Başlıklar:

Dentistry (Other)

Dergi:

European Oral Research Vol.58 Issue 1, pp.22-29

Belge Tipi:

Makale

Yayın Tarihi:

1/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001311474

pISSN:

2630-6158

Anahtar kelimeler:

Özet:

 Purpose: The aim of this study is to compare the biocompatibility of two different resin composites after polymerization under two different light sources in three different time periods. Materials and Methods: 72 polyethylene tubes polymerized with 2 different resin composites and 2 different light sources Elipar S10 and Valo  Group 1: Kalore Elipar S10 KE, Group 2: Kalore Valo KV, Group 3: Essentia Elipar S10 EE, Group 4: Essentia Valo EV were implanted in the dorsal connective tissue of 18 rats. 24 empty polyethylene tubes Group 5: Control group were implanted in the dorsal connective tissue of 6 rats. Then, the rats were sacrificed after 7th, 15th and 30th days in each time intervals n8. Biopsy samples were stained with HE and examined for inflammation, necrosis, macrophage infiltrate, giant cell and fibrous capsule criteria. Immunohistochemical staining was performed to evaluate proinflammatory cytokines IL-1β, IL-6 and IL-8. Results: When the composite groups and the control groups were compared; there was difference statistically significant for the criteria of inflammation at 7th and 15th days, there was no statistical difference between the time points in terms of fibrous capsule and necrosis. When the composite groups and control groups were evaluated in terms of proinflammatory cytokines; statistically significant differences were found at 7th, 15th and 30th days. Conclusion: All CRs used in this study showed acceptable biocompatibility in the subcutaneous tissues of rats after polymerization with different light sources.

 Purpose: The aim of this study is to compare the biocompatibility of two different resin composites after polymerization under two different light sources in three different time periods. Materials and Methods: 72 polyethylene tubes polymerized with 2 different resin composites and 2 different light sources Elipar S10 and Valo  Group 1: Kalore Elipar S10 KE, Group 2: Kalore Valo KV, Group 3: Essentia Elipar S10 EE, Group 4: Essentia Valo EV were implanted in the dorsal connective tissue of 18 rats. 24 empty polyethylene tubes Group 5: Control group were implanted in the dorsal connective tissue of 6 rats. Then, the rats were sacrificed after 7th, 15th and 30th days in each time intervals n8. Biopsy samples were stained with HE and examined for inflammation, necrosis, macrophage infiltrate, giant cell and fibrous capsule criteria. Immunohistochemical staining was performed to evaluate proinflammatory cytokines IL-1β, IL-6 and IL-8. Results: When the composite groups and the control groups were compared; there was difference statistically significant for the criteria of inflammation at 7th and 15th days, there was no statistical difference between the time points in terms of fibrous capsule and necrosis. When the composite groups and control groups were evaluated in terms of proinflammatory cytokines; statistically significant differences were found at 7th, 15th and 30th days. Conclusion: All CRs used in this study showed acceptable biocompatibility in the subcutaneous tissues of rats after polymerization with different light sources.

 Purpose: The aim of this study is to compare the biocompatibility of two different resin composites after polymerization under two different light sources in three different time periods. Materials and Methods: 72 polyethylene tubes polymerized with 2 different resin composites and 2 different light sources Elipar S10 and Valo  Group 1: Kalore Elipar S10 KE, Group 2: Kalore Valo KV, Group 3: Essentia Elipar S10 EE, Group 4: Essentia Valo EV were implanted in the dorsal connective tissue of 18 rats. 24 empty polyethylene tubes Group 5: Control group were implanted in the dorsal connective tissue of 6 rats. Then, the rats were sacrificed after 7th, 15th and 30th days in each time intervals n8. Biopsy samples were stained with HE and examined for inflammation, necrosis, macrophage infiltrate, giant cell and fibrous capsule criteria. Immunohistochemical staining was performed to evaluate proinflammatory cytokines IL-1β, IL-6 and IL-8. Results: When the composite groups and the control groups were compared; there was difference statistically significant for the criteria of inflammation at 7th and 15th days, there was no statistical difference between the time points in terms of fibrous capsule and necrosis. When the composite groups and control groups were evaluated in terms of proinflammatory cytokines; statistically significant differences were found at 7th, 15th and 30th days. Conclusion: All CRs used in this study showed acceptable biocompatibility in the subcutaneous tissues of rats after polymerization with different light sources.

 Purpose: The aim of this study is to compare the biocompatibility of two different resin composites after polymerization under two different light sources in three different time periods. Materials and Methods: 72 polyethylene tubes polymerized with 2 different resin composites and 2 different light sources Elipar S10 and Valo  Group 1: Kalore Elipar S10 KE, Group 2: Kalore Valo KV, Group 3: Essentia Elipar S10 EE, Group 4: Essentia Valo EV were implanted in the dorsal connective tissue of 18 rats. 24 empty polyethylene tubes Group 5: Control group were implanted in the dorsal connective tissue of 6 rats. Then, the rats were sacrificed after 7th, 15th and 30th days in each time intervals n8. Biopsy samples were stained with HE and examined for inflammation, necrosis, macrophage infiltrate, giant cell and fibrous capsule criteria. Immunohistochemical staining was performed to evaluate proinflammatory cytokines IL-1β, IL-6 and IL-8. Results: When the composite groups and the control groups were compared; there was difference statistically significant for the criteria of inflammation at 7th and 15th days, there was no statistical difference between the time points in terms of fibrous capsule and necrosis. When the composite groups and control groups were evaluated in terms of proinflammatory cytokines; statistically significant differences were found at 7th, 15th and 30th days. Conclusion: All CRs used in this study showed acceptable biocompatibility in the subcutaneous tissues of rats after polymerization with different light sources.

Makale detayları

Biocompatibility of different resin composites after polymerization with two light curing units: an immunohistochemical study

Yazarlar:

İrem İpek | Murat Ünal | Tülay Koç

Yayıncı:

Istanbul University

Ana Başlıklar:

Dentistry (Other)

Dergi:

European Oral Research Vol.58 Issue 1, pp.22-29

Belge Tipi:

Makale

Yayın Tarihi:

1/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001311474

pISSN:

2630-6158

Composite resins

light sources

biocompatibility

rat

immunohistochemistry

Sayı

Makale detayları

Biocompatibility of different resin composites after polymerization with two light curing units: an immunohistochemical study

Yazarlar: İrem İpek | Murat Ünal | Tülay Koç

Yayıncı: Istanbul University

Ana Başlıklar: Dentistry (Other)

Dergi: European Oral Research Vol.58 Issue 1, pp.22-29

Belge Tipi: Makale

Yayın Tarihi: 1/2024

Belge Dili: İngilizce

Document ID (Org No.): 2001311474

pISSN: 2630-6158

Composite resins

light sources

biocompatibility

rat

immunohistochemistry

Sayı

Yazarlar:

İrem İpek | Murat Ünal | Tülay Koç

Yayıncı:

Istanbul University

Ana Başlıklar:

Dentistry (Other)

Dergi:

European Oral Research Vol.58 Issue 1, pp.22-29

Belge Tipi:

Makale

Yayın Tarihi:

1/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001311474

pISSN:

2630-6158