Differential Diagnostic Value of Serum Procalcitonin and Iron Levels in Diarrheic Neonatal Calves Caused by Escherichia coli and Rotavirus

Şükrü Değirmençay; Muhammed Sertaç Eroğlu; Emre Eren

Makale detayları

Differential Diagnostic Value of Serum Procalcitonin and Iron Levels in Diarrheic Neonatal Calves Caused by Escherichia coli and Rotavirus

Yazarlar:

Şükrü Değirmençay | Muhammed Sertaç Eroğlu | Emre Eren

Yayıncı:

Afyon Kocatepe University

Ana Başlıklar:

Veteriner Bilimleri

Dergi:

Kocatepe Veteriner Dergisi Vol.16 Issue 1, pp.77-85

Belge Tipi:

Makale

Yayın Tarihi:

3/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001282462

pISSN:

1308-1594

Anahtar kelimeler:

Özet:

 The most common enteropathogens causing diarrhea in neonatal calves are Escherichia coli E. coli and rotavirus. Procalcitonin PCT is a parameter that has recently become widely used to determine whether infectious diseases are caused by bacteria. Iron is an essential nutrient for almost all bacterial species, and serum iron levels are used as an inflammatory biomarker. Therefore, in this study, we aimed to investigate the differential diagnosis value of serum iron and procalcitonin levels in E. coli and rotavirus diarrhea. The material of the study consisted of 30 calves 1-15 days old. Three groups were formed as: E. coli n10, rotavirus n10 and control n10. Calves in the E. coli group had the highest PCT P0.005 and CRP P0.003 levels, as well as the lowest Fe P0.000 levels. As a result, it was determined that serum Fe levels could be used as an inflammatory marker and PCT levels higher than 50 pgmL could be used in the differential diagnosis of E. coli diarrhea in calves with 100 sensitivity and 100 specificity.

 The most common enteropathogens causing diarrhea in neonatal calves are Escherichia coli E. coli and rotavirus. Procalcitonin PCT is a parameter that has recently become widely used to determine whether infectious diseases are caused by bacteria. Iron is an essential nutrient for almost all bacterial species, and serum iron levels are used as an inflammatory biomarker. Therefore, in this study, we aimed to investigate the differential diagnosis value of serum iron and procalcitonin levels in E. coli and rotavirus diarrhea. The material of the study consisted of 30 calves 1-15 days old. Three groups were formed as: E. coli n10, rotavirus n10 and control n10. Calves in the E. coli group had the highest PCT P0.005 and CRP P0.003 levels, as well as the lowest Fe P0.000 levels. As a result, it was determined that serum Fe levels could be used as an inflammatory marker and PCT levels higher than 50 pgmL could be used in the differential diagnosis of E. coli diarrhea in calves with 100 sensitivity and 100 specificity.

 The most common enteropathogens causing diarrhea in neonatal calves are Escherichia coli E. coli and rotavirus. Procalcitonin PCT is a parameter that has recently become widely used to determine whether infectious diseases are caused by bacteria. Iron is an essential nutrient for almost all bacterial species, and serum iron levels are used as an inflammatory biomarker. Therefore, in this study, we aimed to investigate the differential diagnosis value of serum iron and procalcitonin levels in E. coli and rotavirus diarrhea. The material of the study consisted of 30 calves 1-15 days old. Three groups were formed as: E. coli n10, rotavirus n10 and control n10. Calves in the E. coli group had the highest PCT P0.005 and CRP P0.003 levels, as well as the lowest Fe P0.000 levels. As a result, it was determined that serum Fe levels could be used as an inflammatory marker and PCT levels higher than 50 pgmL could be used in the differential diagnosis of E. coli diarrhea in calves with 100 sensitivity and 100 specificity.

 Yeni doğan buzağılarda ishale neden olan en yaygın patojenler Escherichia coli E. coli ve rotavirüstür. Prokalsitonin PCT, son zamanlarda bulaşıcı hastalıkların etiyolojisinin bakteriyel olup olmadığını belirlemek için yaygın olarak kullanılan bir parametredir. Demir Fe neredeyse tüm bakteri türleri için temel bir besin olup serum Fe düzeyleri yangısal bir biyobelirteç olarak kullanılmaktadır. Bu yüzden bu çalışmada E. coli ve rotavirüs ishallerinde serum Fe ve PCT düzeylerinin ayırıcı tanı değerini araştırmayı amaçladık. Çalışmanın materyalini 1-15 günlük 30 buzağı oluşturdu. Buzağılar E. coli n10, rotavirüs n10 ve kontrol n10 grubu olmak üzere 3 gruba ayrıldı. En yüksek PCT P0.005 ve CRP P0.003 değerleri ve en düşük Fe P0.000 değerleri E. coli grubundaki buzağılarda saptandı. Sonuç olarak, serum Fe düzeylerinin inflamatuar belirteç olarak kullanılabileceği ve 50 pgmLden yüksek PCT düzeylerinin buzağılarda E. coliye bağlı ishalin ayırıcı tanısında 100 duyarlılık ve 100 özgüllük ile kullanılabileceği belirlendi.

Makale detayları

Differential Diagnostic Value of Serum Procalcitonin and Iron Levels in Diarrheic Neonatal Calves Caused by Escherichia coli and Rotavirus

Yazarlar:

Şükrü Değirmençay | Muhammed Sertaç Eroğlu | Emre Eren

Yayıncı:

Afyon Kocatepe University

Ana Başlıklar:

Veteriner Bilimleri

Dergi:

Kocatepe Veteriner Dergisi Vol.16 Issue 1, pp.77-85

Belge Tipi:

Makale

Yayın Tarihi:

3/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001282462

pISSN:

1308-1594

Diarrhea

Escherichia coli

Iron levels

Procalcitonin

Rotavirus

Diarrhea

Escherichia coli

Iron levels

Procalcitonin

Rotavirus

Sayı

Makale detayları

Yazarlar: Şükrü Değirmençay | Muhammed Sertaç Eroğlu | Emre Eren

Yayıncı: Afyon Kocatepe University

Ana Başlıklar: Veteriner Bilimleri

Dergi: Kocatepe Veteriner Dergisi Vol.16 Issue 1, pp.77-85

Belge Tipi: Makale

Yayın Tarihi: 3/2023

Belge Dili: İngilizce

Document ID (Org No.): 2001282462

pISSN: 1308-1594

Sayı

Yazarlar:

Şükrü Değirmençay | Muhammed Sertaç Eroğlu | Emre Eren

Yayıncı:

Afyon Kocatepe University

Ana Başlıklar:

Veteriner Bilimleri

Dergi:

Kocatepe Veteriner Dergisi Vol.16 Issue 1, pp.77-85

Belge Tipi:

Makale

Yayın Tarihi:

3/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001282462

pISSN:

1308-1594