In-vitro Activity of Tigecycline against Methicillin-Resistant Staphylococcus aureus Isolated from Wounds of Burn Patients in Tripoli-Libya

Abdulazziz Zorgani; Omar Elahmer; Hisham Ziglam; Khalifa Sifaw Ghenghesh

doi:https://doi.org/10.5799/ahinjs.02.2012.03.0053

Makale detayları

In-vitro Activity of Tigecycline against Methicillin-Resistant Staphylococcus aureus Isolated from Wounds of Burn Patients in Tripoli-Libya

Yazarlar:

Abdulazziz Zorgani | Omar Elahmer | Hisham Ziglam | Khalifa Sifaw Ghenghesh

Yayıncı:

Sağlık Araştırmaları Derneği

Dergi:

Journal of Microbiology and Infectious Diseases 2012 Vol.2 Issue 03, pp.109-112

Belge Tipi:

Makale

Yayın Tarihi:

8/2012

Belge Dili:

İngilizce

Document ID (Org No.):

2000488007

Sıklık:

Üç Aylık

eISSN:

2146-9369

pISSN:

2146-3158

DOI:

https://doi.org/10.5799/ahinjs.02.2012.03.0053

Özet:

 

Objectives: Tigecycline is a new glycylcycline group antibiotic with broad-spectrum activity. In the present study we     	report on in vitro activity of tigecycline as well as the comparator antimicrobials linezolid and quinupristin/dalfopristin     	against methicillin-susceptible Staphylococcus aureus (MSSA) and methicillin resistant Staphylococcus aureus (MRSA)     	strains isolated from burn wounds in Tripoli-Libya.     	Materials and methods: Included in the study 155 MSSA and 144 MRSA isolates from wounds of burn patients and     	identiied by PCR. The susceptibility of MSSA and MRSA isolates to tigecycline, linezolid and quinupristin/dalfopristin     	was determined by the disc diffusion technique.     	Results: Of the MSSA and MRSA isolates examined, susceptibility to tigecycline was observed in 96.8% and 95.8%, to     	linezolid in 97.4% and 96.5% and to quinupristin/dalfopristin in 98.1% and 97.2%, respectively.     	Conclusion: Tigecycline showed excellent in-vitro activity against MSSA and MRSA similar to the comparator drugs (i.e.     	linezolid and quinupristin/dalfopristin). However, tigecycline should be used to treat serious infections when no other     	option exists.

Makale detayları

In-vitro Activity of Tigecycline against Methicillin-Resistant Staphylococcus aureus Isolated from Wounds of Burn Patients in Tripoli-Libya

Yazarlar: Abdulazziz Zorgani | Omar Elahmer | Hisham Ziglam | Khalifa Sifaw Ghenghesh

Yayıncı: Sağlık Araştırmaları Derneği

Dergi: Journal of Microbiology and Infectious Diseases 2012 Vol.2 Issue 03, pp.109-112

Belge Tipi: Makale

Yayın Tarihi: 8/2012

Belge Dili: İngilizce

Document ID (Org No.): 2000488007

Sıklık: Üç Aylık

eISSN: 2146-9369

pISSN: 2146-3158

DOI: https://doi.org/10.5799/ahinjs.02.2012.03.0053

Sayı

Yazarlar:

Abdulazziz Zorgani | Omar Elahmer | Hisham Ziglam | Khalifa Sifaw Ghenghesh

Yayıncı:

Sağlık Araştırmaları Derneği

Dergi:

Journal of Microbiology and Infectious Diseases 2012 Vol.2 Issue 03, pp.109-112

Belge Tipi:

Makale

Yayın Tarihi:

8/2012

Belge Dili:

İngilizce

Document ID (Org No.):

2000488007

Sıklık:

Üç Aylık

eISSN:

2146-9369

pISSN:

2146-3158

DOI:

https://doi.org/10.5799/ahinjs.02.2012.03.0053