Evaluation of Serum Cortisol Level, Hepatitis B and C Virus Infection and Elevated Aminotransferase Enzymes in a Group of Patients with Oral Lichen Planus

Hakan Yülek; Filiz Mediha Namdar Pekiner

Makale detayları

Evaluation of Serum Cortisol Level, Hepatitis B and C Virus Infection and Elevated Aminotransferase Enzymes in a Group of Patients with Oral Lichen Planus

Yazarlar:

Hakan Yülek | Filiz Mediha Namdar Pekiner

Yayıncı:

Marmara University

Ana Başlıklar:

Oral and Maxillofacial Radiology

Dergi:

Clinical and Experimental Health Sciences Vol.14 Issue 4, pp.889-894

Belge Tipi:

Makale

Yayın Tarihi:

12/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001329786

pISSN:

2459-1459

Anahtar kelimeler:

Özet:

 Objective: Oral Lichen planus OLP is a common oral disease that can be caused by a variety of circumstances, including the hepatitis B and C virus HCV. Stress, as a psychological component, raises cortisol levels, which is linked to a cytokine imbalance that may predispose to the development of autoimmune disorders. An association between OLP and serum cortisol levels has been also widely established. In this study, we aimed to evaluate the relationship of serum cortisol levels, hepatitis BC virus infections and alanine transaminase ALT, aspartate transaminase AST in patients with oral lichen planus and to compare to healthy controls. Method: Forty adult patients with OLP and 40 age gender matched healthy controls were participated in the study. All patients were subjected to routine blood test and the estimation of serum cortisol levels, detection of anti-HCV antibody, hepatitis B surface antigen HBsAg, alanine transaminase ALT, aspartate transaminase AST by using the enzyme immunoassay. The data were statistically analyzed using Student-t, Mann-Whitney U, Chi-Square and Fischers Exact test. Results: Serum cortisol level of OLP patients was found to be 13.385.93, and that of the control group was 12.803.93. The OLP patients ALT-AST levels were 19.9110.66, 20.819.85, and those of the control group were 19.9110.66, 20.819.85, respectively. There was no statistical difference of serum cortisol levels, hepatitis BC virus infections and ALT-AST levels in OLP patient compared to the healthy control group p.05. Conclusion: This study identified that there was no association between OLP and healthy controls regarding elevated serum cortisol levels, hepatitis BC virus infection and aminotransferaze enzymes.

 Objective: Oral Lichen planus OLP is a common oral disease that can be caused by a variety of circumstances, including the hepatitis B and C virus HCV. Stress, as a psychological component, raises cortisol levels, which is linked to a cytokine imbalance that may predispose to the development of autoimmune disorders. An association between OLP and serum cortisol levels has been also widely established. In this study, we aimed to evaluate the relationship of serum cortisol levels, hepatitis BC virus infections and alanine transaminase ALT, aspartate transaminase AST in patients with oral lichen planus and to compare to healthy controls. Method: Forty adult patients with OLP and 40 age gender matched healthy controls were participated in the study. All patients were subjected to routine blood test and the estimation of serum cortisol levels, detection of anti-HCV antibody, hepatitis B surface antigen HBsAg, alanine transaminase ALT, aspartate transaminase AST by using the enzyme immunoassay. The data were statistically analyzed using Student-t, Mann-Whitney U, Chi-Square and Fischers Exact test. Results: Serum cortisol level of OLP patients was found to be 13.385.93, and that of the control group was 12.803.93. The OLP patients ALT-AST levels were 19.9110.66, 20.819.85, and those of the control group were 19.9110.66, 20.819.85, respectively. There was no statistical difference of serum cortisol levels, hepatitis BC virus infections and ALT-AST levels in OLP patient compared to the healthy control group p.05. Conclusion: This study identified that there was no association between OLP and healthy controls regarding elevated serum cortisol levels, hepatitis BC virus infection and aminotransferaze enzymes.

 Objective: Oral Lichen planus OLP is a common oral disease that can be caused by a variety of circumstances, including the hepatitis B and C virus HCV. Stress, as a psychological component, raises cortisol levels, which is linked to a cytokine imbalance that may predispose to the development of autoimmune disorders. An association between OLP and serum cortisol levels has been also widely established. In this study, we aimed to evaluate the relationship of serum cortisol levels, hepatitis BC virus infections and alanine transaminase ALT, aspartate transaminase AST in patients with oral lichen planus and to compare to healthy controls. Method: Forty adult patients with OLP and 40 age gender matched healthy controls were participated in the study. All patients were subjected to routine blood test and the estimation of serum cortisol levels, detection of anti-HCV antibody, hepatitis B surface antigen HBsAg, alanine transaminase ALT, aspartate transaminase AST by using the enzyme immunoassay. The data were statistically analyzed using Student-t, Mann-Whitney U, Chi-Square and Fischers Exact test. Results: Serum cortisol level of OLP patients was found to be 13.385.93, and that of the control group was 12.803.93. The OLP patients ALT-AST levels were 19.9110.66, 20.819.85, and those of the control group were 19.9110.66, 20.819.85, respectively. There was no statistical difference of serum cortisol levels, hepatitis BC virus infections and ALT-AST levels in OLP patient compared to the healthy control group p.05. Conclusion: This study identified that there was no association between OLP and healthy controls regarding elevated serum cortisol levels, hepatitis BC virus infection and aminotransferaze enzymes.

 Objective: Oral Lichen planus OLP is a common oral disease that can be caused by a variety of circumstances, including the hepatitis B and C virus HCV. Stress, as a psychological component, raises cortisol levels, which is linked to a cytokine imbalance that may predispose to the development of autoimmune disorders. An association between OLP and serum cortisol levels has been also widely established. In this study, we aimed to evaluate the relationship of serum cortisol levels, hepatitis BC virus infections and alanine transaminase ALT, aspartate transaminase AST in patients with oral lichen planus and to compare to healthy controls. Method: Forty adult patients with OLP and 40 age gender matched healthy controls were participated in the study. All patients were subjected to routine blood test and the estimation of serum cortisol levels, detection of anti-HCV antibody, hepatitis B surface antigen HBsAg, alanine transaminase ALT, aspartate transaminase AST by using the enzyme immunoassay. The data were statistically analyzed using Student-t, Mann-Whitney U, Chi-Square and Fischers Exact test. Results: Serum cortisol level of OLP patients was found to be 13.385.93, and that of the control group was 12.803.93. The OLP patients ALT-AST levels were 19.9110.66, 20.819.85, and those of the control group were 19.9110.66, 20.819.85, respectively. There was no statistical difference of serum cortisol levels, hepatitis BC virus infections and ALT-AST levels in OLP patient compared to the healthy control group p.05. Conclusion: This study identified that there was no association between OLP and healthy controls regarding elevated serum cortisol levels, hepatitis BC virus infection and aminotransferaze enzymes.

Makale detayları

Evaluation of Serum Cortisol Level, Hepatitis B and C Virus Infection and Elevated Aminotransferase Enzymes in a Group of Patients with Oral Lichen Planus

Yazarlar:

Hakan Yülek | Filiz Mediha Namdar Pekiner

Yayıncı:

Marmara University

Ana Başlıklar:

Oral and Maxillofacial Radiology

Dergi:

Clinical and Experimental Health Sciences Vol.14 Issue 4, pp.889-894

Belge Tipi:

Makale

Yayın Tarihi:

12/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001329786

pISSN:

2459-1459

Oral lichen planus

oral mucosal diseases

hepatitis

serum cortisol

Sayı

Makale detayları

Evaluation of Serum Cortisol Level, Hepatitis B and C Virus Infection and Elevated Aminotransferase Enzymes in a Group of Patients with Oral Lichen Planus

Yazarlar: Hakan Yülek | Filiz Mediha Namdar Pekiner

Yayıncı: Marmara University

Ana Başlıklar: Oral and Maxillofacial Radiology

Dergi: Clinical and Experimental Health Sciences Vol.14 Issue 4, pp.889-894

Belge Tipi: Makale

Yayın Tarihi: 12/2024

Belge Dili: İngilizce

Document ID (Org No.): 2001329786

pISSN: 2459-1459

Oral lichen planus

oral mucosal diseases

hepatitis

serum cortisol

Sayı

Yazarlar:

Hakan Yülek | Filiz Mediha Namdar Pekiner

Yayıncı:

Marmara University

Ana Başlıklar:

Oral and Maxillofacial Radiology

Dergi:

Clinical and Experimental Health Sciences Vol.14 Issue 4, pp.889-894

Belge Tipi:

Makale

Yayın Tarihi:

12/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001329786

pISSN:

2459-1459