Protective effect of different layers of onion extracts (Allium cepa L.) on markers of oxidative stress in erythrocytes

Syed RİZVİ

Makale detayları

Protective effect of different layers of onion extracts (Allium cepa L.) on markers of oxidative stress in erythrocytes

Yazarlar:

Syed RİZVİ

Yayıncı:

Hücresel Sinir Bilimleri ve Oksidatif Stres Derneği

Dergi:

Cell Membranes and Free Radical Research 2011 Vol.3 Issue 2, pp.171-177

Belge Tipi:

Makale

Yayın Tarihi:

8/2013

Belge Dili:

İngilizce

Document ID (Org No.):

2000708994

Sıklık:

Üç Yıllık

eISSN:

2149-7222

Özet:

 

Onions (Allium cepa L.) are the rich source of flavonoids, consisting mainly quercetin-3,4´-O-diglucoside (QDG) and quercetin-4´-O-monoglucoside (QMG), as major flavonoids. In the present study, we report the in vitro protective effect of different layers of onion extract on biomarkers of oxidative stress and on free radical induced oxidative hemolysis in erythrocytes. Results show a significant protection of oxidative stress by onion extract on erythrocyte subjected to tert-butyl hydroperoxide (t-BHP) treatment, as evidenced by the decrease in malondialdehyde (MDA) and increase in reduced glutathione (GSH) content. Onion extracts also showed significant protection of the erythrocyte from oxidative hemolysis. Quercetin (at micromolar concentration) showed significant antioxidant effect in protecting erythrocytes from t-BHP induced oxidative changes. The results are more pronounced for outer layers as compared to inner layers, suggesting that the outermost living layers had higher antioxidant activities compared to innermost layers.

Makale detayları

Protective effect of different layers of onion extracts (Allium cepa L.) on markers of oxidative stress in erythrocytes

Yazarlar: Syed RİZVİ

Yayıncı: Hücresel Sinir Bilimleri ve Oksidatif Stres Derneği

Dergi: Cell Membranes and Free Radical Research 2011 Vol.3 Issue 2, pp.171-177

Belge Tipi: Makale

Yayın Tarihi: 8/2013

Belge Dili: İngilizce

Document ID (Org No.): 2000708994

Sıklık: Üç Yıllık

eISSN: 2149-7222

Sayı

Yazarlar:

Syed RİZVİ

Yayıncı:

Hücresel Sinir Bilimleri ve Oksidatif Stres Derneği

Dergi:

Cell Membranes and Free Radical Research 2011 Vol.3 Issue 2, pp.171-177

Belge Tipi:

Makale

Yayın Tarihi:

8/2013

Belge Dili:

İngilizce

Document ID (Org No.):

2000708994

Sıklık:

Üç Yıllık

eISSN:

2149-7222