Effect of Low-Intensity Microwave Radiation on Rat Kidney: An Ultrastructural Study

Yusuf NERGİZ

Makale detayları

Effect of Low-Intensity Microwave Radiation on Rat Kidney: An Ultrastructural Study

Yazarlar:

Yusuf NERGİZ

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2000 Vol.30 Issue 3, pp.223-228

Belge Tipi:

Makale

Yayın Tarihi:

2/2000

Belge Dili:

Türkçe

Document ID (Org No.):

2000757613

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144

Anahtar kelimeler:

Özet:

 

Exposure to low-intensity  microwave radiation for prolonged periods is  known to be a potential factor inducing  visceral damage. There are several studies in  the literature demonstrating the harmful  effects of such radiation on the kidney of  laboratory animals. Our aim was to  determine the effect of low intensity  microwave radiation on rat kidney at the  light and electron microscopic level.  Animals (28 rats) in the experiment group  were exposed to 2.65 mW/cm 2 radition  (9450 MHz) for 1 h per day during 26 and  52 days respectively and tissue samples of  these animals were examined and compared  with those of the control group.  At the light microscopic level most significant  changes were observed in the 52.0-days  exposure group. In the renal tubular  epithelium there was extensive apical  vesiculation almost totally obliterating the  lumen. Cytoplasmic vacuolization of the  epithelial cells was not prominent in the  26.0-day group but also became most  significant in the 52.0-day group.  Degenerative changes in the kidney glomeruli  were also most prominent in the 52.0-day  group at light and electron microscopic levels.  At the ultrastructural level renal tubular  epithelium and glomeruli reflected features  of early necrotic changes gradually increasing  as the exposure period increased. Glomerular  sclerosis was the end stage of these  degenerative changes as clearly outlined at  the ultrastructural level.  Our findings clearly demonstrate the harmful  effects of low-intensity microwave radiation  on kidney parenchyma in an exposure-period  dependent manner.

 

Exposure to low-intensity  microwave radiation for prolonged periods is  known to be a potential factor inducing  visceral damage. There are several studies in  the literature demonstrating the harmful  effects of such radiation on the kidney of  laboratory animals. Our aim was to  determine the effect of low intensity  microwave radiation on rat kidney at the  light and electron microscopic level.  Animals (28 rats) in the experiment group  were exposed to 2.65 mW/cm 2 radition  (9450 MHz) for 1 h per day during 26 and  52 days respectively and tissue samples of  these animals were examined and compared  with those of the control group.  At the light microscopic level most significant  changes were observed in the 52.0-days  exposure group. In the renal tubular  epithelium there was extensive apical  vesiculation almost totally obliterating the  lumen. Cytoplasmic vacuolization of the  epithelial cells was not prominent in the  26.0-day group but also became most  significant in the 52.0-day group.  Degenerative changes in the kidney glomeruli  were also most prominent in the 52.0-day  group at light and electron microscopic levels.  At the ultrastructural level renal tubular  epithelium and glomeruli reflected features  of early necrotic changes gradually increasing  as the exposure period increased. Glomerular  sclerosis was the end stage of these  degenerative changes as clearly outlined at  the ultrastructural level.  Our findings clearly demonstrate the harmful  effects of low-intensity microwave radiation  on kidney parenchyma in an exposure-period  dependent manner.

Makale detayları

Effect of Low-Intensity Microwave Radiation on Rat Kidney: An Ultrastructural Study

Yazarlar:

Yusuf NERGİZ

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2000 Vol.30 Issue 3, pp.223-228

Belge Tipi:

Makale

Yayın Tarihi:

2/2000

Belge Dili:

Türkçe

Document ID (Org No.):

2000757613

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144

Low-intensity microwave radiation

kidney

rat.

Sayı

Makale detayları

Effect of Low-Intensity Microwave Radiation on Rat Kidney: An Ultrastructural Study

Yazarlar: Yusuf NERGİZ

Yayıncı: TUBITAK

Dergi: Turkish Journal of Medical Sciences 2000 Vol.30 Issue 3, pp.223-228

Belge Tipi: Makale

Yayın Tarihi: 2/2000

Belge Dili: Türkçe

Document ID (Org No.): 2000757613

Sıklık: İki Aylık

eISSN: 1303-6165

pISSN: 1300-0144

Low-intensity microwave radiation

kidney

rat.

Sayı

Yazarlar:

Yusuf NERGİZ

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2000 Vol.30 Issue 3, pp.223-228

Belge Tipi:

Makale

Yayın Tarihi:

2/2000

Belge Dili:

Türkçe

Document ID (Org No.):

2000757613

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144