Antioxidant  activity,  chemical  composition  and  therapeutic activity of essential oils from certain  composition,  Lamiaceae species in Türkiye

Burçak Gürbüz; Gökçe Şeker Karatoprak; Selen İlgün

Makale detayları

Antioxidant activity, chemical composition and therapeutic activity of essential oils from certain composition, Lamiaceae species in Türkiye

Yazarlar:

Burçak Gürbüz | Gökçe Şeker Karatoprak | Selen İlgün

Yayıncı:

Marmara University

Ana Başlıklar:

Pharmacognosy

Dergi:

Journal of Research in Pharmacy Vol.29 Issue 1, pp.30-51

Belge Tipi:

Makale

Yayın Tarihi:

3/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001339591

pISSN:

2630-6344

Anahtar kelimeler:

Özet:

 The study examined the antioxidant, antimicrobial, and potential anticancer properties of lavandin Lavandula x intermedia Grosso, oregano Origanum vulgare Uluğ Bey, and sage Salvia officinalis Beyhekim essential oils EOs. Chemical analysis revealed that oregano is rich in carvacrol 81.23, cymene 5.51, and 18 cineole 2.13. Sage contains notable quantities of α-thujone 17.47, camphor 13.59, and borneol 12.14. Lavandin is predominantly composed of linalool 41.10, linalyl acetate 16.66, and camphor 10.01. The antimicrobial tests demonstrated that lavandin EOs exhibited a high inhibition rate of 90.77 at 1000 μgmL, which subsequently decreased with lower concentrations. The oregano essential oils demonstrated robust antimicrobial activity across all concentrations, with a 10.97 inhibition rate observed even at the lowest concentration. The sage EOs exhibited a rapid decline in antimicrobial activity, reaching 4.97 at the lowest concentration. Both the DPPH and ABTS assays demonstrated that the antioxidant capacity of the essential oils was concentration-dependent. The cytotoxicity values of oregano essential oil were 35.58 at 50 μgmL, 32.39 at 25 μgmL, and 30.92 at 12.5 μgmL. Similar cytotoxicity results were observed for sage and lavandin essential oils. These findings indicate that plant essential oils exert a dose-dependent cytotoxic effect on cell growth, significantly inhibiting cells at high concentrations. The research indicates that essential oils derived from Lamiaceae plants exhibit robust antimicrobial effects against a range of pathogens, suggesting potential applications as alternative therapies for specific microbial infections, comparable to ciprofloxacin at certain concentrations.

 The study examined the antioxidant, antimicrobial, and potential anticancer properties of lavandin Lavandula x intermedia Grosso, oregano Origanum vulgare Uluğ Bey, and sage Salvia officinalis Beyhekim essential oils EOs. Chemical analysis revealed that oregano is rich in carvacrol 81.23, cymene 5.51, and 18 cineole 2.13. Sage contains notable quantities of α-thujone 17.47, camphor 13.59, and borneol 12.14. Lavandin is predominantly composed of linalool 41.10, linalyl acetate 16.66, and camphor 10.01. The antimicrobial tests demonstrated that lavandin EOs exhibited a high inhibition rate of 90.77 at 1000 μgmL, which subsequently decreased with lower concentrations. The oregano essential oils demonstrated robust antimicrobial activity across all concentrations, with a 10.97 inhibition rate observed even at the lowest concentration. The sage EOs exhibited a rapid decline in antimicrobial activity, reaching 4.97 at the lowest concentration. Both the DPPH and ABTS assays demonstrated that the antioxidant capacity of the essential oils was concentration-dependent. The cytotoxicity values of oregano essential oil were 35.58 at 50 μgmL, 32.39 at 25 μgmL, and 30.92 at 12.5 μgmL. Similar cytotoxicity results were observed for sage and lavandin essential oils. These findings indicate that plant essential oils exert a dose-dependent cytotoxic effect on cell growth, significantly inhibiting cells at high concentrations. The research indicates that essential oils derived from Lamiaceae plants exhibit robust antimicrobial effects against a range of pathogens, suggesting potential applications as alternative therapies for specific microbial infections, comparable to ciprofloxacin at certain concentrations.

 The study examined the antioxidant, antimicrobial, and potential anticancer properties of lavandin Lavandula x intermedia Grosso, oregano Origanum vulgare Uluğ Bey, and sage Salvia officinalis Beyhekim essential oils EOs. Chemical analysis revealed that oregano is rich in carvacrol 81.23, cymene 5.51, and 18 cineole 2.13. Sage contains notable quantities of α-thujone 17.47, camphor 13.59, and borneol 12.14. Lavandin is predominantly composed of linalool 41.10, linalyl acetate 16.66, and camphor 10.01. The antimicrobial tests demonstrated that lavandin EOs exhibited a high inhibition rate of 90.77 at 1000 μgmL, which subsequently decreased with lower concentrations. The oregano essential oils demonstrated robust antimicrobial activity across all concentrations, with a 10.97 inhibition rate observed even at the lowest concentration. The sage EOs exhibited a rapid decline in antimicrobial activity, reaching 4.97 at the lowest concentration. Both the DPPH and ABTS assays demonstrated that the antioxidant capacity of the essential oils was concentration-dependent. The cytotoxicity values of oregano essential oil were 35.58 at 50 μgmL, 32.39 at 25 μgmL, and 30.92 at 12.5 μgmL. Similar cytotoxicity results were observed for sage and lavandin essential oils. These findings indicate that plant essential oils exert a dose-dependent cytotoxic effect on cell growth, significantly inhibiting cells at high concentrations. The research indicates that essential oils derived from Lamiaceae plants exhibit robust antimicrobial effects against a range of pathogens, suggesting potential applications as alternative therapies for specific microbial infections, comparable to ciprofloxacin at certain concentrations.

 The study examined the antioxidant, antimicrobial, and potential anticancer properties of lavandin Lavandula x intermedia Grosso, oregano Origanum vulgare Uluğ Bey, and sage Salvia officinalis Beyhekim essential oils EOs. Chemical analysis revealed that oregano is rich in carvacrol 81.23, cymene 5.51, and 18 cineole 2.13. Sage contains notable quantities of α-thujone 17.47, camphor 13.59, and borneol 12.14. Lavandin is predominantly composed of linalool 41.10, linalyl acetate 16.66, and camphor 10.01. The antimicrobial tests demonstrated that lavandin EOs exhibited a high inhibition rate of 90.77 at 1000 μgmL, which subsequently decreased with lower concentrations. The oregano essential oils demonstrated robust antimicrobial activity across all concentrations, with a 10.97 inhibition rate observed even at the lowest concentration. The sage EOs exhibited a rapid decline in antimicrobial activity, reaching 4.97 at the lowest concentration. Both the DPPH and ABTS assays demonstrated that the antioxidant capacity of the essential oils was concentration-dependent. The cytotoxicity values of oregano essential oil were 35.58 at 50 μgmL, 32.39 at 25 μgmL, and 30.92 at 12.5 μgmL. Similar cytotoxicity results were observed for sage and lavandin essential oils. These findings indicate that plant essential oils exert a dose-dependent cytotoxic effect on cell growth, significantly inhibiting cells at high concentrations. The research indicates that essential oils derived from Lamiaceae plants exhibit robust antimicrobial effects against a range of pathogens, suggesting potential applications as alternative therapies for specific microbial infections, comparable to ciprofloxacin at certain concentrations.

Makale detayları

Antioxidant activity, chemical composition and therapeutic activity of essential oils from certain composition, Lamiaceae species in Türkiye

Yazarlar:

Burçak Gürbüz | Gökçe Şeker Karatoprak | Selen İlgün

Yayıncı:

Marmara University

Ana Başlıklar:

Pharmacognosy

Dergi:

Journal of Research in Pharmacy Vol.29 Issue 1, pp.30-51

Belge Tipi:

Makale

Yayın Tarihi:

3/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001339591

pISSN:

2630-6344

Origanum vulgare subs. hirtum

Salvia officinalis L.

lavandula x intermedia

antioxidant

antimicrobial

cytotoxicity

Sayı

Makale detayları

Antioxidant activity, chemical composition and therapeutic activity of essential oils from certain composition, Lamiaceae species in Türkiye

Yazarlar: Burçak Gürbüz | Gökçe Şeker Karatoprak | Selen İlgün

Yayıncı: Marmara University

Ana Başlıklar: Pharmacognosy

Dergi: Journal of Research in Pharmacy Vol.29 Issue 1, pp.30-51

Belge Tipi: Makale

Yayın Tarihi: 3/2025

Belge Dili: İngilizce

Document ID (Org No.): 2001339591

pISSN: 2630-6344

Origanum vulgare subs. hirtum

Salvia officinalis L.

lavandula x intermedia

antioxidant

antimicrobial

cytotoxicity

Sayı

Yazarlar:

Burçak Gürbüz | Gökçe Şeker Karatoprak | Selen İlgün

Yayıncı:

Marmara University

Ana Başlıklar:

Pharmacognosy

Dergi:

Journal of Research in Pharmacy Vol.29 Issue 1, pp.30-51

Belge Tipi:

Makale

Yayın Tarihi:

3/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001339591

pISSN:

2630-6344