Aeroallergen Sensitization in Adults with Allergic Rhinitis: A Single Center Experience in a Tertiary Hospital

Nurgül Sevimli

Makale detayları

Aeroallergen Sensitization in Adults with Allergic Rhinitis: A Single Center Experience in a Tertiary Hospital

Yazarlar:

Nurgül Sevimli

Yayıncı:

Dicle University

Ana Başlıklar:

Sağlık Kurumları Yönetimi | Tıp Eğitimi | Sağlık Hizmetleri ve Sistemleri (Diğer)

Dergi:

Dicle Tıp Dergisi Vol.52 Issue 3, pp.497-506

Belge Tipi:

Makale

Yayın Tarihi:

9/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001358318

pISSN:

1300-2945

Anahtar kelimeler:

Özet:

 Background and Objectives: Aeroallergen sensitization patterns vary by region, influenced by environmental factors such as climate and vegetation. This study aimed to determine the sensitization profile and identify the most common aeroallergens in adult patients presenting with a preliminary diagnosis of allergic rhinitis AR at a tertiary care center in Southeastern Türkiye. Methods: Adult patients 18 years who presented to our immunology-allergy clinic with suspected AR and underwent skin prick testing SPT for inhalant allergens between February 2024-February 2025 were retrospectively analyzed. Demographic and clinical dataincluding total IgE levels, eosinophil counts, and SPT resultswere retrieved from medical records. Results: A total of 658 patients were included; median age was 31 years, and 65 were female. A family history of atopy was present in 28.3, and 36.8 had at least one allergic comorbidity, most commonly asthma 26. Based on symptom severity, 51.3 had mild AR and 48.7 had moderate-to-severe AR. Sensitization to inhalant allergens was identified in 77.4 of patients. The most common aeroallergens were grass pollen mix 40.3, Dermatophagoides farinae 37.7, Dermatophagoides pteronyssinus 33.3, meadow-grass pollen mix 27.8, and cockroach 24.2. Sensitization to grass pollen mix, weed pollen mix, olive tree pollens, and cockroach was significantly associated with moderate-to-severe AR. Asthma was more prevalent in this group and was strongly linked to sensitization to house dust mites, and dog epithelium p  0.05. Conclusion: Sensitization to pollens and indoor allergens is associated with increased AR severity and asthma. Identifying regional sensitization profiles may support more accurate diagnosis and personalized treatment strategies.

 Background and Objectives: Aeroallergen sensitization patterns vary by region, influenced by environmental factors such as climate and vegetation. This study aimed to determine the sensitization profile and identify the most common aeroallergens in adult patients presenting with a preliminary diagnosis of allergic rhinitis AR at a tertiary care center in Southeastern Türkiye. Methods: Adult patients 18 years who presented to our immunology-allergy clinic with suspected AR and underwent skin prick testing SPT for inhalant allergens between February 2024-February 2025 were retrospectively analyzed. Demographic and clinical dataincluding total IgE levels, eosinophil counts, and SPT resultswere retrieved from medical records. Results: A total of 658 patients were included; median age was 31 years, and 65 were female. A family history of atopy was present in 28.3, and 36.8 had at least one allergic comorbidity, most commonly asthma 26. Based on symptom severity, 51.3 had mild AR and 48.7 had moderate-to-severe AR. Sensitization to inhalant allergens was identified in 77.4 of patients. The most common aeroallergens were grass pollen mix 40.3, Dermatophagoides farinae 37.7, Dermatophagoides pteronyssinus 33.3, meadow-grass pollen mix 27.8, and cockroach 24.2. Sensitization to grass pollen mix, weed pollen mix, olive tree pollens, and cockroach was significantly associated with moderate-to-severe AR. Asthma was more prevalent in this group and was strongly linked to sensitization to house dust mites, and dog epithelium p  0.05. Conclusion: Sensitization to pollens and indoor allergens is associated with increased AR severity and asthma. Identifying regional sensitization profiles may support more accurate diagnosis and personalized treatment strategies.

 Background and Objectives: Aeroallergen sensitization patterns vary by region, influenced by environmental factors such as climate and vegetation. This study aimed to determine the sensitization profile and identify the most common aeroallergens in adult patients presenting with a preliminary diagnosis of allergic rhinitis AR at a tertiary care center in Southeastern Türkiye. Methods: Adult patients 18 years who presented to our immunology-allergy clinic with suspected AR and underwent skin prick testing SPT for inhalant allergens between February 2024-February 2025 were retrospectively analyzed. Demographic and clinical dataincluding total IgE levels, eosinophil counts, and SPT resultswere retrieved from medical records. Results: A total of 658 patients were included; median age was 31 years, and 65 were female. A family history of atopy was present in 28.3, and 36.8 had at least one allergic comorbidity, most commonly asthma 26. Based on symptom severity, 51.3 had mild AR and 48.7 had moderate-to-severe AR. Sensitization to inhalant allergens was identified in 77.4 of patients. The most common aeroallergens were grass pollen mix 40.3, Dermatophagoides farinae 37.7, Dermatophagoides pteronyssinus 33.3, meadow-grass pollen mix 27.8, and cockroach 24.2. Sensitization to grass pollen mix, weed pollen mix, olive tree pollens, and cockroach was significantly associated with moderate-to-severe AR. Asthma was more prevalent in this group and was strongly linked to sensitization to house dust mites, and dog epithelium p  0.05. Conclusion: Sensitization to pollens and indoor allergens is associated with increased AR severity and asthma. Identifying regional sensitization profiles may support more accurate diagnosis and personalized treatment strategies.

 Amaç: Aeroalerjen duyarlılık paternleri, iklim ve bitki örtüsü gibi çevresel faktörlerden etkilenerek bölgelere göre değişiklik gösterir. Bu çalışma, Güneydoğu Türkiyedeki bir üçüncü basamak sağlık merkezine alerjik rinit AR ön tanısıyla başvuran yetişkin hastalarda duyarlılık profilini belirlemeyi ve en sık görülen aeroalerjenleri tespit etmeyi amaçlamıştır. Yöntemler: Şubat 2024-Şubat 2025 arasında immunoloji-alerji polikliniğine AR şüphesiyle başvuran ve inhalan alerjenlere yönelik deri prik testi SPT yapılan 18 yaş ve üzeri yetişkin hastalar retrospektif olarak incelenmiştir. Hastaların demografik ve klinik verileritoplam IgE seviyeleri, eozinofil sayıları ve SPT sonuçları dahiltıbbi kayıtlardan alınmıştır. Bulgular: Çalışmamıza toplam 658 hasta dahil edildi. Hastaların yaş ortancası 31 yıl olup, 65i kadındı. Hastaların 28,3ünde ailede atopi öyküsü bulunurken, 36,8inde en az bir alerjik komorbidite vardı; bunların başında astım 26 gelmekteydi. Semptom şiddetine göre, hastaların 51,3ünde hafif AR, 48,7sinde ise orta-şiddetli AR görüldü. Hastaların 77,4ünde inhalan alerjenlere karşı duyarlılık tespit edildi. En sık görülen aeroalerjenler sırasıyla: Çayır poleni karışımı 40,3, Dermatophagoides farinae 37,7, Dermatophagoides pteronyssinus 33.3, Çayır otu poleni karışımı 27,8, Hamam böceği 24,2 olarak belirlendi. Çayır poleni karışımı, yabani ot poleni karışımı, zeytin ağacı polenleri ve hamam böceğine karşı duyarlılık, orta-şiddetli AR ile anlamlı derecede ilişkiliydi. Astım, bu grupta daha yaygındı ve ev tozu akarları ile köpek epiteline karşı duyarlılıkla güçlü bir bağlantı gösterdi p0.05. Sonuç: Güneydoğu Türkiyedeki alerjik rinit hastalarının alerjen duyarlılık profili hakkında önemli bilgiler sunmaktadır. Bölgenin iklimi ve bitki örtüsü göz önüne alındığında, bu veriler klinik uygulamalarda ve halk sağlığı stratejilerinde değerli bir rehber olabilir.

Makale detayları

Aeroallergen Sensitization in Adults with Allergic Rhinitis: A Single Center Experience in a Tertiary Hospital

Yazarlar:

Nurgül Sevimli

Yayıncı:

Dicle University

Ana Başlıklar:

Sağlık Kurumları Yönetimi | Tıp Eğitimi | Sağlık Hizmetleri ve Sistemleri (Diğer)

Dergi:

Dicle Tıp Dergisi Vol.52 Issue 3, pp.497-506

Belge Tipi:

Makale

Yayın Tarihi:

9/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001358318

pISSN:

1300-2945

Aeroallergen

allergic rhinitis

asthma

skin prick test

sensitizationAeroalerjen

alerjik rinit

astım

deri prik testi

duyarlılık

Sayı

Makale detayları

Yazarlar: Nurgül Sevimli

Yayıncı: Dicle University

Ana Başlıklar: Sağlık Kurumları Yönetimi | Tıp Eğitimi | Sağlık Hizmetleri ve Sistemleri (Diğer)

Dergi: Dicle Tıp Dergisi Vol.52 Issue 3, pp.497-506

Belge Tipi: Makale

Yayın Tarihi: 9/2025

Belge Dili: İngilizce

Document ID (Org No.): 2001358318

pISSN: 1300-2945

Sayı

Yazarlar:

Nurgül Sevimli

Yayıncı:

Dicle University

Ana Başlıklar:

Sağlık Kurumları Yönetimi | Tıp Eğitimi | Sağlık Hizmetleri ve Sistemleri (Diğer)

Dergi:

Dicle Tıp Dergisi Vol.52 Issue 3, pp.497-506

Belge Tipi:

Makale

Yayın Tarihi:

9/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001358318

pISSN:

1300-2945