Cytotoxic Effects of Hawthorn and Elderberry Extracts on 3T3 Fibroblast Cell Line

Gizem BAYSAN; R. Bugra HUSEMOGLU; Hasan HAVITÇIOĞLU

Makale detayları

Cytotoxic Effects of Hawthorn and Elderberry Extracts on 3T3 Fibroblast Cell Line

Yazarlar:

Gizem BAYSAN | R. Bugra HUSEMOGLU | Hasan HAVITÇIOĞLU

Yayıncı:

Eskişehir Osmangazi University

Ana Başlıklar:

Kimya mühendisliği

Dergi:

Journal of Medical Innovation and Technology 2020 Vol.2 Issue 1, pp.85-91

Belge Tipi:

Makale

Yayın Tarihi:

6/2020

Belge Dili:

İngilizce

Document ID (Org No.):

2000486782

Sıklık:

Aylık

eISSN:

2687-3834

pISSN:

2667-8977

Özet:

 


Plants have been used in the medical remedies by countless people since the ancient times. Medicinal plants have multiple benefits for various cases. Nowadays, science is developing in correlation with these medicinal plants. Hawthorn (Crataegus oxyacantha) and elderberry (Sambucus nigra) is used in this study as a medicinal plant. Hawthorn has been claimed to be used in the treatment of heart and blood vessel diseases, chest pain, irregular heartbeat, digestive problems and cholesterol regulation. On the other hand, elderberry has been claimed to be used in inflammation, fever, joint and muscle pain, minor skin conditions, stress and even HIV. In this study, we investigated the cytotoxicity levels of the hawthorn and elderberry extracts with different concentrations on 3T3 murine fibroblast cell line. 1 × 104 cells/well were equally seeded in 96 well plate and incubated for 24 hours to form a half-confluent monolayer.  Treatment medium containing various concentrations of extracts (10, 5, 1, 0.5, 0.1, 0.05 and 0.01 mg/ml) were added per well. The viability analysis was conducted after 48 hours by using the WST-1 colorimetric assay. In conclusion, each concentration used is non-cytotoxic and better proliferation activities were reached by using 0.05 mg/ml concentration for hawthorn and elderberry. 

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Makale detayları

Cytotoxic Effects of Hawthorn and Elderberry Extracts on 3T3 Fibroblast Cell Line

Yazarlar: Gizem BAYSAN | R. Bugra HUSEMOGLU | Hasan HAVITÇIOĞLU

Yayıncı: Eskişehir Osmangazi University

Ana Başlıklar: Kimya mühendisliği

Dergi: Journal of Medical Innovation and Technology 2020 Vol.2 Issue 1, pp.85-91

Belge Tipi: Makale

Yayın Tarihi: 6/2020

Belge Dili: İngilizce

Document ID (Org No.): 2000486782

Sıklık: Aylık

eISSN: 2687-3834

pISSN: 2667-8977

Sayı

Yazarlar:

Gizem BAYSAN | R. Bugra HUSEMOGLU | Hasan HAVITÇIOĞLU

Yayıncı:

Eskişehir Osmangazi University

Ana Başlıklar:

Kimya mühendisliği

Dergi:

Journal of Medical Innovation and Technology 2020 Vol.2 Issue 1, pp.85-91

Belge Tipi:

Makale

Yayın Tarihi:

6/2020

Belge Dili:

İngilizce

Document ID (Org No.):

2000486782

Sıklık:

Aylık

eISSN:

2687-3834

pISSN:

2667-8977