Central corneal thickness in type II diabetes mellitus: is it relatedto the severity of diabetic retinopathy?

Okan TOYGAR; Selçuk SIZMAZ; Aysel PELİT; Baha TOYGAR; Özge Yabaş KIZILOĞLU; Yonca AKOVA

Makale detayları

Central corneal thickness in type II diabetes mellitus: is it relatedto the severity of diabetic retinopathy?

Yazarlar:

Okan TOYGAR | Selçuk SIZMAZ | Aysel PELİT | Baha TOYGAR | Özge Yabaş KIZILOĞLU | Yonca AKOVA

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2015 Vol.45 Issue 3, pp.651-654

Belge Tipi:

Makale

Yayın Tarihi:

8/2015

Belge Dili:

Türkçe

Document ID (Org No.):

2000752703

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144

Anahtar kelimeler:

Özet:

 

Background/aim: To compare the central corneal thickness (CCT) of type II diabetes mellitus patients with age- and sex-matched healthy subjects and to determine the association of the severity of diabetic retinopathy and CCT.  Materials and methods: Type II diabetes mellitus patients without retinopathy, with nonproliferative retinopathy, and with proliferative retinopathy were organized as the three subgroups of the study group, and an age- and sex-matched control group was formed. All subjects underwent full ophthalmological examination and CCT measurement with ultrasonographic pachymetry. CCT values were compared between diabetic and healthy subjects and between the three diabetic subgroups. Correlation analysis was performed to determine any relationship between CCT and intraocular pressure.  Results: The average CCT was significantly higher in diabetic patients than in the control group (P = 0.04). CCT in diabetic patients without retinopathy did not significantly differ from that of patients with retinopathy (P = 0.64). Similarly, there was no significant difference in CCT between nonproliferative and proliferative diabetic retinopathy patients (P = 0.47). In the whole study population, CCT was significantly correlated with intraocular pressure (P < 0.01).   Conclusion: CCT is significantly increased in type II diabetes mellitus patients with respect to controls. Retinal disease severity does not seem to have an effect on corneal thickness.

 

Background/aim: To compare the central corneal thickness (CCT) of type II diabetes mellitus patients with age- and sex-matched healthy subjects and to determine the association of the severity of diabetic retinopathy and CCT.  Materials and methods: Type II diabetes mellitus patients without retinopathy, with nonproliferative retinopathy, and with proliferative retinopathy were organized as the three subgroups of the study group, and an age- and sex-matched control group was formed. All subjects underwent full ophthalmological examination and CCT measurement with ultrasonographic pachymetry. CCT values were compared between diabetic and healthy subjects and between the three diabetic subgroups. Correlation analysis was performed to determine any relationship between CCT and intraocular pressure.  Results: The average CCT was significantly higher in diabetic patients than in the control group (P = 0.04). CCT in diabetic patients without retinopathy did not significantly differ from that of patients with retinopathy (P = 0.64). Similarly, there was no significant difference in CCT between nonproliferative and proliferative diabetic retinopathy patients (P = 0.47). In the whole study population, CCT was significantly correlated with intraocular pressure (P < 0.01).   Conclusion: CCT is significantly increased in type II diabetes mellitus patients with respect to controls. Retinal disease severity does not seem to have an effect on corneal thickness.

Makale detayları

Central corneal thickness in type II diabetes mellitus: is it relatedto the severity of diabetic retinopathy?

Yazarlar: Okan TOYGAR | Selçuk SIZMAZ | Aysel PELİT | Baha TOYGAR | Özge Yabaş KIZILOĞLU | Yonca AKOVA

Yayıncı: TUBITAK

Dergi: Turkish Journal of Medical Sciences 2015 Vol.45 Issue 3, pp.651-654

Belge Tipi: Makale

Yayın Tarihi: 8/2015

Belge Dili: Türkçe

Document ID (Org No.): 2000752703

Sıklık: İki Aylık

eISSN: 1303-6165

pISSN: 1300-0144

Central corneal thickness

diabetes mellitus

diabetic retinopathy

pachymetry

Sayı

Yazarlar:

Okan TOYGAR | Selçuk SIZMAZ | Aysel PELİT | Baha TOYGAR | Özge Yabaş KIZILOĞLU | Yonca AKOVA

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2015 Vol.45 Issue 3, pp.651-654

Belge Tipi:

Makale

Yayın Tarihi:

8/2015

Belge Dili:

Türkçe

Document ID (Org No.):

2000752703

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144