Evaluation of antimicrobial activity of five Vincetoxicum taxa growing in Turkey

Sevda Güzel Kara; Mahmut Ülger; Gönül Aslan; Gamze Kökdil

Makale detayları

Evaluation of antimicrobial activity of five Vincetoxicum taxa growing in Turkey

Yazarlar:

Sevda Güzel Kara | Mahmut Ülger | Gönül Aslan | Gamze Kökdil

Yayıncı:

Marmara University

Ana Başlıklar:

Pharmacognosy

Dergi:

Journal of Research in Pharmacy Vol.22 Issue 3, pp.365-373

Belge Tipi:

Makale

Yayın Tarihi:

6/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001346279

pISSN:

2630-6344

Anahtar kelimeler:

Özet:

 The antibacterial, antifungal and antimycobacterial effects of ethanolic extracts obtained from aerial parts and roots of five Vincetoxicum taxa V. canescens subsp. canescens, V. canescens subsp. pedunculata, V. parviflorum, V. fuscatum subsp. fuscatum and V. fuscatum subsp. boissieri were tested against two Gram  bacterial strains Staphylococcus aureus and Bacillus subtilis, three Gram - bacterial strains Escherichia coli, Acinetobacter baumannii and Aeromonas hydrophila, three fungal strains Candida glabrata, Candida parapsilosis and Candida tropicalis and Mycobacterium tuberculosis by using the broth dilution method. Ethambutol, Isoniazid, Ampicillin and Fluconazole were used as reference antimicrobial agents. All tested extracts showed significant antibacterial activity against A. baumannii with MIC values ranging from 31.25 to 62.5 µgml when compared to reference drug Ampicillin with 125 µgml MIC value. Moreover, the extracts obtained from aerial parts of V. fuscatum subsp. boissieri and roots of V. canescens subsp. pedunculata were found the most effective extracts against A. baumannii with 31.25 µgml MIC value.

 The antibacterial, antifungal and antimycobacterial effects of ethanolic extracts obtained from aerial parts and roots of five Vincetoxicum taxa V. canescens subsp. canescens, V. canescens subsp. pedunculata, V. parviflorum, V. fuscatum subsp. fuscatum and V. fuscatum subsp. boissieri were tested against two Gram  bacterial strains Staphylococcus aureus and Bacillus subtilis, three Gram - bacterial strains Escherichia coli, Acinetobacter baumannii and Aeromonas hydrophila, three fungal strains Candida glabrata, Candida parapsilosis and Candida tropicalis and Mycobacterium tuberculosis by using the broth dilution method. Ethambutol, Isoniazid, Ampicillin and Fluconazole were used as reference antimicrobial agents. All tested extracts showed significant antibacterial activity against A. baumannii with MIC values ranging from 31.25 to 62.5 µgml when compared to reference drug Ampicillin with 125 µgml MIC value. Moreover, the extracts obtained from aerial parts of V. fuscatum subsp. boissieri and roots of V. canescens subsp. pedunculata were found the most effective extracts against A. baumannii with 31.25 µgml MIC value.

 The antibacterial, antifungal and antimycobacterial effects of ethanolic extracts obtained from aerial parts and roots of five Vincetoxicum taxa V. canescens subsp. canescens, V. canescens subsp. pedunculata, V. parviflorum, V. fuscatum subsp. fuscatum and V. fuscatum subsp. boissieri were tested against two Gram  bacterial strains Staphylococcus aureus and Bacillus subtilis, three Gram - bacterial strains Escherichia coli, Acinetobacter baumannii and Aeromonas hydrophila, three fungal strains Candida glabrata, Candida parapsilosis and Candida tropicalis and Mycobacterium tuberculosis by using the broth dilution method. Ethambutol, Isoniazid, Ampicillin and Fluconazole were used as reference antimicrobial agents. All tested extracts showed significant antibacterial activity against A. baumannii with MIC values ranging from 31.25 to 62.5 µgml when compared to reference drug Ampicillin with 125 µgml MIC value. Moreover, the extracts obtained from aerial parts of V. fuscatum subsp. boissieri and roots of V. canescens subsp. pedunculata were found the most effective extracts against A. baumannii with 31.25 µgml MIC value.

 The antibacterial, antifungal and antimycobacterial effects of ethanolic extracts obtained from aerial parts and roots of five Vincetoxicum taxa V. canescens subsp. canescens, V. canescens subsp. pedunculata, V. parviflorum, V. fuscatum subsp. fuscatum and V. fuscatum subsp. boissieri were tested against two Gram  bacterial strains Staphylococcus aureus and Bacillus subtilis, three Gram - bacterial strains Escherichia coli, Acinetobacter baumannii and Aeromonas hydrophila, three fungal strains Candida glabrata, Candida parapsilosis and Candida tropicalis and Mycobacterium tuberculosis by using the broth dilution method. Ethambutol, Isoniazid, Ampicillin and Fluconazole were used as reference antimicrobial agents. All tested extracts showed significant antibacterial activity against A. baumannii with MIC values ranging from 31.25 to 62.5 µgml when compared to reference drug Ampicillin with 125 µgml MIC value. Moreover, the extracts obtained from aerial parts of V. fuscatum subsp. boissieri and roots of V. canescens subsp. pedunculata were found the most effective extracts against A. baumannii with 31.25 µgml MIC value.

Makale detayları

Evaluation of antimicrobial activity of five Vincetoxicum taxa growing in Turkey

Yazarlar:

Sevda Güzel Kara | Mahmut Ülger | Gönül Aslan | Gamze Kökdil

Yayıncı:

Marmara University

Ana Başlıklar:

Pharmacognosy

Dergi:

Journal of Research in Pharmacy Vol.22 Issue 3, pp.365-373

Belge Tipi:

Makale

Yayın Tarihi:

6/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001346279

pISSN:

2630-6344

Vincetoxicum

antimicrobial activity

plant extract

broth microdilution method

Acinetobacter baumannii

Sayı

Makale detayları

Evaluation of antimicrobial activity of five Vincetoxicum taxa growing in Turkey

Yazarlar: Sevda Güzel Kara | Mahmut Ülger | Gönül Aslan | Gamze Kökdil

Yayıncı: Marmara University

Ana Başlıklar: Pharmacognosy

Dergi: Journal of Research in Pharmacy Vol.22 Issue 3, pp.365-373

Belge Tipi: Makale

Yayın Tarihi: 6/2025

Belge Dili: İngilizce

Document ID (Org No.): 2001346279

pISSN: 2630-6344

Vincetoxicum

antimicrobial activity

plant extract

broth microdilution method

Acinetobacter baumannii

Sayı

Yazarlar:

Sevda Güzel Kara | Mahmut Ülger | Gönül Aslan | Gamze Kökdil

Yayıncı:

Marmara University

Ana Başlıklar:

Pharmacognosy

Dergi:

Journal of Research in Pharmacy Vol.22 Issue 3, pp.365-373

Belge Tipi:

Makale

Yayın Tarihi:

6/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001346279

pISSN:

2630-6344