Plasmid-mediated colistin resistance mcr-1 in a clinical isolate of Escherichia coli ST19 in Algeria

Selma BOUHERAOUA; Farida ASSAOUS; Nora ZOURDANİ; Naima TAHRAT; Hassiba Tali MAAMAR

doi:https://doi.org/10.5799/jmid.839476

Makale detayları

Plasmid-mediated colistin resistance mcr-1 in a clinical isolate of Escherichia coli ST19 in Algeria

Yazarlar:

Selma BOUHERAOUA | Farida ASSAOUS | Nora ZOURDANİ | Naima TAHRAT | Hassiba Tali MAAMAR

Yayıncı:

Sağlık Araştırmaları Derneği

Ana Başlıklar:

Sağlık teşvikleri

Dergi:

Journal of Microbiology and Infectious Diseases 2020 Vol.10 Issue 04, pp.222-224

Belge Tipi:

Makale

Yayın Tarihi:

12/2020

Belge Dili:

İngilizce

Document ID (Org No.):

2000487232

Sıklık:

Üç Aylık

eISSN:

2146-9369

pISSN:

2146-3158

DOI:

https://doi.org/10.5799/jmid.839476

Özet:

 

We describe the emergence of plasmid-mediated colistin resistance mcr-1 in a clinical isolate of Escherichia coli ST19. The strain was isolated from a urine sample of a 75-year-old male patient. The identification was carried out by an automated system. The antibiogram was performed according to CLSI recommendations. The colistin MIC was determined by broth micro-dilution according to CA-SFM/EUCAST criteria. The detection of mcr-1 was carried out by immunochromatographic test and PCR mcr-1. Genetic transfers and determination of the plasmid incompatibility group were made. The ST was carried out by MLST using the Pasteur scheme.
The strain has a high-level penicillinase resistance phenotype. It was susceptible to amikacin and resistant to gentamicin, tobramycin, fluoroquinolones, tetracycline, chloramphenicol, and cotrimoxazole. The strain was resistant to colistin (MIC ꞊ 4 μg/ml).
The genetic transfer is given a colistin-resistant transconjugant. The plasmid carrying mcr-1 gene belongs to the incompatibility group IncHI2.The strain belongs to ST19. J Microbiol Infect Dis 2019; 10(4):222-224.

Makale detayları

Plasmid-mediated colistin resistance mcr-1 in a clinical isolate of Escherichia coli ST19 in Algeria

Yazarlar: Selma BOUHERAOUA | Farida ASSAOUS | Nora ZOURDANİ | Naima TAHRAT | Hassiba Tali MAAMAR

Yayıncı: Sağlık Araştırmaları Derneği

Ana Başlıklar: Sağlık teşvikleri

Dergi: Journal of Microbiology and Infectious Diseases 2020 Vol.10 Issue 04, pp.222-224

Belge Tipi: Makale

Yayın Tarihi: 12/2020

Belge Dili: İngilizce

Document ID (Org No.): 2000487232

Sıklık: Üç Aylık

eISSN: 2146-9369

pISSN: 2146-3158

DOI: https://doi.org/10.5799/jmid.839476

Sayı

Yazarlar:

Selma BOUHERAOUA | Farida ASSAOUS | Nora ZOURDANİ | Naima TAHRAT | Hassiba Tali MAAMAR

Yayıncı:

Sağlık Araştırmaları Derneği

Ana Başlıklar:

Sağlık teşvikleri

Dergi:

Journal of Microbiology and Infectious Diseases 2020 Vol.10 Issue 04, pp.222-224

Belge Tipi:

Makale

Yayın Tarihi:

12/2020

Belge Dili:

İngilizce

Document ID (Org No.):

2000487232

Sıklık:

Üç Aylık

eISSN:

2146-9369

pISSN:

2146-3158

DOI:

https://doi.org/10.5799/jmid.839476