Studies on the Chemical Constituents of Thymus serpyllum

Shahid AZIZ

Makale detayları

Studies on the Chemical Constituents of Thymus serpyllum

Yazarlar:

Shahid AZIZ

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Chemistry 2008 Vol.32 Issue 5, pp.605-614

Belge Tipi:

Makale

Yayın Tarihi:

4/2008

Belge Dili:

Türkçe

Document ID (Org No.):

2000728446

Sıklık:

İki Aylık

eISSN:

1303-6130

pISSN:

1300-0527

Özet:

 

Phytochemical investigations on the methanolic extract of  Thymus serpyllum resulted in the isolation of 2 new compounds,  3-ketopentatriacontanoic acid (1) and 27-ketotriacontanol (2).  The  extract also afforded 3 known compounds, 3 b-hydroxyolean-12-en-  28-oic acid (3), 3-O-b-D-glucopyranosyl-sitosterol (4), and  dihydroursonic acid (5), detected for the first time from Thymus  serpyllum.  The structures of the new compounds were elucidated by  spectroscopic methods, while the known compounds were identified on  the basis of their spectral data and literature evidence.  The hexane  and ethyl acetate soluble portions of the methanolic extract showed  significant antifungal activity, whereas the chloroform soluble  portion and the remaining methanol extract showed moderate activity.

 

Phytochemical investigations on the methanolic extract of  Thymus serpyllum resulted in the isolation of 2 new compounds,  3-ketopentatriacontanoic acid (1) and 27-ketotriacontanol (2).  The  extract also afforded 3 known compounds, 3 b-hydroxyolean-12-en-  28-oic acid (3), 3-O-b-D-glucopyranosyl-sitosterol (4), and  dihydroursonic acid (5), detected for the first time from Thymus  serpyllum.  The structures of the new compounds were elucidated by  spectroscopic methods, while the known compounds were identified on  the basis of their spectral data and literature evidence.  The hexane  and ethyl acetate soluble portions of the methanolic extract showed  significant antifungal activity, whereas the chloroform soluble  portion and the remaining methanol extract showed moderate activity.

Makale detayları

Studies on the Chemical Constituents of Thymus serpyllum

Yazarlar: Shahid AZIZ

Yayıncı: TUBITAK

Dergi: Turkish Journal of Chemistry 2008 Vol.32 Issue 5, pp.605-614

Belge Tipi: Makale

Yayın Tarihi: 4/2008

Belge Dili: Türkçe

Document ID (Org No.): 2000728446

Sıklık: İki Aylık

eISSN: 1303-6130

pISSN: 1300-0527

Sayı

Yazarlar:

Shahid AZIZ

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Chemistry 2008 Vol.32 Issue 5, pp.605-614

Belge Tipi:

Makale

Yayın Tarihi:

4/2008

Belge Dili:

Türkçe

Document ID (Org No.):

2000728446

Sıklık:

İki Aylık

eISSN:

1303-6130

pISSN:

1300-0527