Helicobacter pylori infection in pediatric patients with celiac disease: A single-center experience

Sibel Yavuz; Haci Ballı; Hatice Uygun; Merve Kılıç Çil

Makale detayları

Helicobacter pylori infection in pediatric patients with celiac disease: A single-center experience

Yazarlar:

Sibel Yavuz | Haci Ballı | Hatice Uygun | Merve Kılıç Çil

Yayıncı:

Adıyaman University

Ana Başlıklar:

Çocuk Gastroenterolojisi

Dergi:

Adıyaman Üniversitesi Sağlık Bilimleri Dergisi Vol.10 Issue 1, pp.55-59

Belge Tipi:

Makale

Yayın Tarihi:

4/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001315238

pISSN:

2458-9179

Anahtar kelimeler:

Özet:

 Aim: There are numerous studies investigating the relationship between celiac disease CD and Helicobacter pylori H. pylori. In this study, we aimed to compare the prevalence of coexisting H. pylori infection and CD in pediatric patients diagnosed with celiac disease at our clinic versus an age-matched control group. Materials and Methods: A total of 198 patients with celiac disease and 131 sex and age -matched controls undergoing upper gastrointestinal endoscopy due to dyspeptic complaints were included in this study. The prevalence of H. pylori was compared between the groups. Results: Of the 198 patients with CD included in the study, 66 33.3 were male and 132 66.7 were female, while in the control group, 36 27.5 were male, and 95 72.5 were female. 89 44 of the patients with CD and 70 53.4 of the controls were H. pylori-positive. There was no statistically significant difference in the distribution of Marsh scores between the H. pylori-negative and -positive groups. Conclusion: The association between celiac disease and H. pylori remains controversial. Thus, multicenter studies are warranted to evaluate the role of H. pylori in the pathogenesis of celiac disease.

 Aim: There are numerous studies investigating the relationship between celiac disease CD and Helicobacter pylori H. pylori. In this study, we aimed to compare the prevalence of coexisting H. pylori infection and CD in pediatric patients diagnosed with celiac disease at our clinic versus an age-matched control group. Materials and Methods: A total of 198 patients with celiac disease and 131 sex and age -matched controls undergoing upper gastrointestinal endoscopy due to dyspeptic complaints were included in this study. The prevalence of H. pylori was compared between the groups. Results: Of the 198 patients with CD included in the study, 66 33.3 were male and 132 66.7 were female, while in the control group, 36 27.5 were male, and 95 72.5 were female. 89 44 of the patients with CD and 70 53.4 of the controls were H. pylori-positive. There was no statistically significant difference in the distribution of Marsh scores between the H. pylori-negative and -positive groups. Conclusion: The association between celiac disease and H. pylori remains controversial. Thus, multicenter studies are warranted to evaluate the role of H. pylori in the pathogenesis of celiac disease.

 Aim: There are numerous studies investigating the relationship between celiac disease CD and Helicobacter pylori H. pylori. In this study, we aimed to compare the prevalence of coexisting H. pylori infection and CD in pediatric patients diagnosed with celiac disease at our clinic versus an age-matched control group. Materials and Methods: A total of 198 patients with celiac disease and 131 sex and age -matched controls undergoing upper gastrointestinal endoscopy due to dyspeptic complaints were included in this study. The prevalence of H. pylori was compared between the groups. Results: Of the 198 patients with CD included in the study, 66 33.3 were male and 132 66.7 were female, while in the control group, 36 27.5 were male, and 95 72.5 were female. 89 44 of the patients with CD and 70 53.4 of the controls were H. pylori-positive. There was no statistically significant difference in the distribution of Marsh scores between the H. pylori-negative and -positive groups. Conclusion: The association between celiac disease and H. pylori remains controversial. Thus, multicenter studies are warranted to evaluate the role of H. pylori in the pathogenesis of celiac disease.

 Amaç: Çölyak hastalığı ve Helicobacter pylori H. pylori arasındaki ilişkiyi araştıran birçok çalışma vardır. Biz çalışmamızda; kliniğimizde çölyak hastalığı tanısı almış hastalarda, Helicobacter pylori birlikteliğini ve yaş uyumlu kontrol grubu ile karşılaştırmayı amaçladık Gereç ve Yöntem: Çalışmaya 198 çölyak hastası, yaş ve cinsiyet uyumlu, dispeptik şikayetleri nedeni ile üst gastrointestinal sistem endoskopisi yapılmış 131 kontrol hastası dahil edildi. İki grubun H. pylori prevalansları saptanarak aralarında farklılık olup olmadığı araştırıldı. Bulgular: Çalışmaya alınan 198 çölyak hastasının 66 33,3sı erkek, 132 66,7si kız hasta ve kontrol grubunun 36 27.5 erkek, 95 72.5 kız hasta idi. Çölyak hastalığı olan 198 hastanın 89unda 44, kontrol grubundaki 131 hastanın 70inde53.4 H. pylori pozitif saptandı. H. pylori pozitif ve negatif gruplar arasında Marsh skoru dağılımı açısından istatistiksel anlamlı fark saptanmadı. Sonuç: Çölyak hastalığı ile H. pylori arasındaki ilişki tartışmalı olmakla birlikte çölyak hastalığı patogenezinde H. pylorinin rolünü değerlendirmek için çok merkezli çalışmalara ihtiyaç vardır.

Makale detayları

Helicobacter pylori infection in pediatric patients with celiac disease: A single-center experience

Yazarlar:

Sibel Yavuz | Haci Ballı | Hatice Uygun | Merve Kılıç Çil

Yayıncı:

Adıyaman University

Ana Başlıklar:

Çocuk Gastroenterolojisi

Dergi:

Adıyaman Üniversitesi Sağlık Bilimleri Dergisi Vol.10 Issue 1, pp.55-59

Belge Tipi:

Makale

Yayın Tarihi:

4/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001315238

pISSN:

2458-9179

Celiac Disease

H. Pylori

PrevalenceÇölyak Hastalığı

H. Pylori

Prevalans

Sayı

Makale detayları

Helicobacter pylori infection in pediatric patients with celiac disease: A single-center experience

Yazarlar: Sibel Yavuz | Haci Ballı | Hatice Uygun | Merve Kılıç Çil

Yayıncı: Adıyaman University

Ana Başlıklar: Çocuk Gastroenterolojisi

Dergi: Adıyaman Üniversitesi Sağlık Bilimleri Dergisi Vol.10 Issue 1, pp.55-59

Belge Tipi: Makale

Yayın Tarihi: 4/2024

Belge Dili: İngilizce

Document ID (Org No.): 2001315238

pISSN: 2458-9179

Celiac Disease

H. Pylori

PrevalenceÇölyak Hastalığı

H. Pylori

Prevalans

Sayı

Yazarlar:

Sibel Yavuz | Haci Ballı | Hatice Uygun | Merve Kılıç Çil

Yayıncı:

Adıyaman University

Ana Başlıklar:

Çocuk Gastroenterolojisi

Dergi:

Adıyaman Üniversitesi Sağlık Bilimleri Dergisi Vol.10 Issue 1, pp.55-59

Belge Tipi:

Makale

Yayın Tarihi:

4/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001315238

pISSN:

2458-9179