Antioxidant Potential of ulva rigida c. Agardh Extract: Protection from Oxidative Stress Hypothyroidism

S. TAŞ

Makale detayları

Antioxidant Potential of ulva rigida c. Agardh Extract: Protection from Oxidative Stress Hypothyroidism

Yazarlar:

S. TAŞ

Yayıncı:

İzzet KARA

Dergi:

International Journal of Secondary Metabolite 2014 Vol.1 Issue 1, pp.70-0

Belge Tipi:

Makale

Yayın Tarihi:

7/2014

Belge Dili:

Türkçe

Document ID (Org No.):

2000472145

Sıklık:

Üç Aylık

eISSN:

2148-6905

Özet:

 

The purpose of this study was to evaluate the effects of Ulva rigida C. Agardh, one of the green algae, on and antioxidative system in the propylthiouracil (PTU)-induced hypothyroid rats. Thirty-two rats randomly divided into four groups: control (C), control+U. rigida extract (C+UR), hypothyroid (H) and hypothyroid+U. rigida extract (H+UR). U. rigida (2%) was administered in drinking water for 5 weeks after the induction of hypothyroidism. Hypothyroid rats were under oxidative stress as reflected by icreased plasma and tissue malondialdehyde (MDA) levels. U. rigida reduced serum total cholesterol and,- triglyceride levels and plasma and heart skeletal muscle, liver and,- kidney tissue MDA levels in the H+UR group. Serum total cholesterol and tissues MDA levels were reduced in the C+UR group. Whole blood glutathione peroxidase and erythrocyte superoxide dismutase activities were increased in the H+UR and C+UR groups compared with those of te respective control groups. Paraoxonase and arylesterase activities were lower in the H group and U. rigida increased paraoxonase and arylesterase activities in C+UR and H+UR groups. We conclude that hypothyroidism is associated with oxidative stress and, U. rigida extract might have a potential use as a protective antioxidant agent in hypothroidism.

Makale detayları

Antioxidant Potential of ulva rigida c. Agardh Extract: Protection from Oxidative Stress Hypothyroidism

Yazarlar: S. TAŞ

Yayıncı: İzzet KARA

Dergi: International Journal of Secondary Metabolite 2014 Vol.1 Issue 1, pp.70-0

Belge Tipi: Makale

Yayın Tarihi: 7/2014

Belge Dili: Türkçe

Document ID (Org No.): 2000472145

Sıklık: Üç Aylık

eISSN: 2148-6905

Sayı

Yazarlar:

S. TAŞ

Yayıncı:

İzzet KARA

Dergi:

International Journal of Secondary Metabolite 2014 Vol.1 Issue 1, pp.70-0

Belge Tipi:

Makale

Yayın Tarihi:

7/2014

Belge Dili:

Türkçe

Document ID (Org No.):

2000472145

Sıklık:

Üç Aylık

eISSN:

2148-6905