Effect of vitamin D deficiency on uric acid/HDL cholesterol ratio

Ülkem Şen Uzeli; Ayşe Gülşen Doğan

Makale detayları

Effect of vitamin D deficiency on uric acid/HDL cholesterol ratio

Yazarlar:

Ülkem Şen Uzeli | Ayşe Gülşen Doğan

Yayıncı:

MediHealth Academy Yayıncılık

Ana Başlıklar:

İç Hastalıkları

Dergi:

Journal of Medicine and Palliative Care Vol.5 Issue 3, pp.177-181

Belge Tipi:

Makale

Yayın Tarihi:

6/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001321078

pISSN:

2717-7505

Anahtar kelimeler:

Özet:

 Aims: It has been suggested that vitamin D deficiency is involved in the etiology of cardiovascular diseases. High uric acid and low HDL cholesterol levels are critical risk factors for cardiovascular diseases. High uric acid levels, high total cholesterol and triglyceride levels, and low HDL-C levels are often encountered in cases with vitamin D deficiency. Our study aimed to investigate the relationship between vitamin D levels and uric acid HDL-C UHR and plasma atherogenic index PAI, triglyceride HDL-C in patients with vitamin D deficiency. Methods: This retrospective study included patients whose vitamin D levels were checked in our clinic. The subjects were divided into two groups according to their vitamin D levels and the relationship between laboratory variables, such as uric acid, HDL cholesterol, UHR, and plasma atherogenic index, was examined. Results: A total of 675 patients, 167 24.7 males and 508 75.3 females, were included in the study. The mean age of the patients was 53.615.2 years. It was found that patients with vitamin D deficiency had high UHR and PAI levels and low HDL-C levels p0.001, p0.025; p0.032, p0.016. Conclusion Our results suggest that vitamin D deficiency has a positive correlation with HDL cholesterol levels and an impact on the risk of cardiovascular diseases by increasing the uric acidHDL ratio and plasma atherogenic index.

 Aims: It has been suggested that vitamin D deficiency is involved in the etiology of cardiovascular diseases. High uric acid and low HDL cholesterol levels are critical risk factors for cardiovascular diseases. High uric acid levels, high total cholesterol and triglyceride levels, and low HDL-C levels are often encountered in cases with vitamin D deficiency. Our study aimed to investigate the relationship between vitamin D levels and uric acid HDL-C UHR and plasma atherogenic index PAI, triglyceride HDL-C in patients with vitamin D deficiency. Methods: This retrospective study included patients whose vitamin D levels were checked in our clinic. The subjects were divided into two groups according to their vitamin D levels and the relationship between laboratory variables, such as uric acid, HDL cholesterol, UHR, and plasma atherogenic index, was examined. Results: A total of 675 patients, 167 24.7 males and 508 75.3 females, were included in the study. The mean age of the patients was 53.615.2 years. It was found that patients with vitamin D deficiency had high UHR and PAI levels and low HDL-C levels p0.001, p0.025; p0.032, p0.016. Conclusion Our results suggest that vitamin D deficiency has a positive correlation with HDL cholesterol levels and an impact on the risk of cardiovascular diseases by increasing the uric acidHDL ratio and plasma atherogenic index.

 Aims: It has been suggested that vitamin D deficiency is involved in the etiology of cardiovascular diseases. High uric acid and low HDL cholesterol levels are critical risk factors for cardiovascular diseases. High uric acid levels, high total cholesterol and triglyceride levels, and low HDL-C levels are often encountered in cases with vitamin D deficiency. Our study aimed to investigate the relationship between vitamin D levels and uric acid HDL-C UHR and plasma atherogenic index PAI, triglyceride HDL-C in patients with vitamin D deficiency. Methods: This retrospective study included patients whose vitamin D levels were checked in our clinic. The subjects were divided into two groups according to their vitamin D levels and the relationship between laboratory variables, such as uric acid, HDL cholesterol, UHR, and plasma atherogenic index, was examined. Results: A total of 675 patients, 167 24.7 males and 508 75.3 females, were included in the study. The mean age of the patients was 53.615.2 years. It was found that patients with vitamin D deficiency had high UHR and PAI levels and low HDL-C levels p0.001, p0.025; p0.032, p0.016. Conclusion Our results suggest that vitamin D deficiency has a positive correlation with HDL cholesterol levels and an impact on the risk of cardiovascular diseases by increasing the uric acidHDL ratio and plasma atherogenic index.

 Giriş: Kalp damar hastalıklarının etiyolojisinde d vitamini eksikliğinin de yer aldığı öne sürülmektedir. Yüksek ürikasit düzeyi, düşük HDL-kolesterol düzeyleri kardiyovasküler hastalıklar için önemli birer risk faktördür. D vitamini eksikliğinde ürikasit yüksekliğine, total kolesterol, trigliserit seviyelerinde yüksekliğe ve düşük HDL-K düzeyi ile karşılaşılmaktadır. Biz de çalışmamızda d vitamini eksik olan hastaların D vitamini düzeyleri ile ürikasit HDL-KUHR ve plazma aterojenik indeks PAI, trigliseritHDL-K arasındaki ilişkiyi incelemeyi amaçladık. Metod: Çalışmamız retrospektif bir çalışma olup kliniğimizde D vitamini düzeyi bakılan hastalar dahil edildi. Denekler D vitamini düzeylerine göre iki gruba ayrılarak ürik asit, HDL-kolesterol, UHR, plazma aterojenik indeks gibi laboratuvar değişkenleri ile arasındaki ilişki incelendi. Sonuç: Çalışmada 167 24,7 erkek ve 508 75,3 kadın olmak üzere toplam 675 hasta dahil edildi. Hastaların yaş ortalaması 53,615,2 yıl idi. D vitamini eksik olan hastaların UHR ve PAI düzeylerinin yüksek olduğu, HDL-K düzeylerinin ise düşük olduğu görüldü p0,001, p0,025; p0,032, p0,016. Tartışma: Çalışmamız d vitamini eksikliğinin HDL-Kolesterol düzeyi ile pozitif bir korelasyon olduğu ürikasit HDL oranını ve plazma aterojenik indeksi artırarak kardıyovasküler hastalık riskini üzerinde etkisi olduğu desteklemektedir.

Makale detayları

Effect of vitamin D deficiency on uric acid/HDL cholesterol ratio

Yazarlar:

Ülkem Şen Uzeli | Ayşe Gülşen Doğan

Yayıncı:

MediHealth Academy Yayıncılık

Ana Başlıklar:

İç Hastalıkları

Dergi:

Journal of Medicine and Palliative Care Vol.5 Issue 3, pp.177-181

Belge Tipi:

Makale

Yayın Tarihi:

6/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001321078

pISSN:

2717-7505

Vitamin D

Uric Acid/HDL Cholesterol Ratio

plasma atherogenic indexd vitamini

ÜRİKASİT/HDL-KOLESTEROL ORANI

plazma aterojenik indeksi

Sayı

Makale detayları

Effect of vitamin D deficiency on uric acid/HDL cholesterol ratio

Yazarlar: Ülkem Şen Uzeli | Ayşe Gülşen Doğan

Yayıncı: MediHealth Academy Yayıncılık

Ana Başlıklar: İç Hastalıkları

Dergi: Journal of Medicine and Palliative Care Vol.5 Issue 3, pp.177-181

Belge Tipi: Makale

Yayın Tarihi: 6/2024

Belge Dili: İngilizce

Document ID (Org No.): 2001321078

pISSN: 2717-7505

Vitamin D

Uric Acid/HDL Cholesterol Ratio

plasma atherogenic indexd vitamini

ÜRİKASİT/HDL-KOLESTEROL ORANI

plazma aterojenik indeksi

Sayı

Yazarlar:

Ülkem Şen Uzeli | Ayşe Gülşen Doğan

Yayıncı:

MediHealth Academy Yayıncılık

Ana Başlıklar:

İç Hastalıkları

Dergi:

Journal of Medicine and Palliative Care Vol.5 Issue 3, pp.177-181

Belge Tipi:

Makale

Yayın Tarihi:

6/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001321078

pISSN:

2717-7505