C-Reactive Protein and Serum Amyloid A in Male Dogs after Orchiectomy

Nejra HADŽİMUSİĆ

Makale detayları

C-Reactive Protein and Serum Amyloid A in Male Dogs after Orchiectomy

Yazarlar:

Nejra HADŽİMUSİĆ

Yayıncı:

Erciyes University

Dergi:

Journal of The Faculty of Veterinary Medicine Erciyes University 2018 Vol.15 Issue 1, pp.37-40

Belge Tipi:

Makale

Yayın Tarihi:

4/2018

Belge Dili:

İngilizce

Document ID (Org No.):

2000413311

eISSN:

2667-5498

pISSN:

1304-7280

Özet:

 


The acute-phase response is considered part of the innate immune system. During acute phase response,

concentrations of acute phase proteins occur. Therefore, acute-phase proteins are part of the innate immune response

and its biological function, although variable, generally relate to defense to pathological damage and restoration of

homeostasis. Their levels fluctuate in response to inflammation and tissue injury. The main acute-phase proteins in

dogs are C-reactive protein (CRP) and serum amyloid A (SAA). Surgical trauma has effect on many parts of immunological

and hematological profile. The aim of this study was to determine the perioperative dynamics of CRP and SAA

in male dogs undergoing elective orchiectomy. Blood samples were collectedby jugular venipuncture in the following

order: before the surgery (day zero), on first (day one), third (day three) and seventh (day seven) postoperative day

(POD). As markers of systemic inflammation, CRP and SAA levels was determined by ELISA using commercial kits.

The study showed that the CRP and SAA changes rapidly. The peak CRP and SAA concentrations were detected on

the first day after surgery. Serum CRP concentration on the seventh postoperative day was within physiological ranges,

while SAA concentration was significantly higher. In conclusion, SAA and CRP measurements above basal levels

are clearly indicative of systemic inflammation in dogs.

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Makale detayları

C-Reactive Protein and Serum Amyloid A in Male Dogs after Orchiectomy

Yazarlar: Nejra HADŽİMUSİĆ

Yayıncı: Erciyes University

Dergi: Journal of The Faculty of Veterinary Medicine Erciyes University 2018 Vol.15 Issue 1, pp.37-40

Belge Tipi: Makale

Yayın Tarihi: 4/2018

Belge Dili: İngilizce

Document ID (Org No.): 2000413311

eISSN: 2667-5498

pISSN: 1304-7280

Sayı

Yazarlar:

Nejra HADŽİMUSİĆ

Yayıncı:

Erciyes University

Dergi:

Journal of The Faculty of Veterinary Medicine Erciyes University 2018 Vol.15 Issue 1, pp.37-40

Belge Tipi:

Makale

Yayın Tarihi:

4/2018

Belge Dili:

İngilizce

Document ID (Org No.):

2000413311

eISSN:

2667-5498

pISSN:

1304-7280