The Role of Plasma Endothelin-1 in Preeclampsia

Yalçın KİMYA

Makale detayları

The Role of Plasma Endothelin-1 in Preeclampsia

Yazarlar:

Yalçın KİMYA

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 1999 Vol.29 Issue 1, pp.21-24

Belge Tipi:

Makale

Yayın Tarihi:

12/1998

Belge Dili:

Türkçe

Document ID (Org No.):

2000758119

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144

Anahtar kelimeler:

Özet:

 

Endothelin-1 levels in normal and preeclamptic pregnant women were determined serially to investigate the  correlation between renal function tests and the severity markers of preeclampsia. Plasma endothelin-1 levels were determined in 45 serial plasma samples from 15 pregnant women who subsequently developed preeclampsia, and in 43 plasma samples from 25 women with uncomplicated pregnancies retrospectively. Renal function tests, complete blood counts, urinalysis and blood pressure measurements were performed during antenatal follow-ups of these patients. No correlations were set between plasma endothelin-1 levels and renal function tests, thrombocyte and white blood cell counts, proteinuria, systolic and diastolic blood pressures. There was no significant difference between the mean plasma  endothelin-1 concentrations of the preeclamptic and uncomplicated groups at all gestational weeks but at the time of delivery. None of the endothelin-1 values at any gestational week differed significantly from any other in the study group; therefore, the risk of subsequent development of preeclampsia could not be estimated by plasma endothelin-1 measurements.

 

Endothelin-1 levels in normal and preeclamptic pregnant women were determined serially to investigate the  correlation between renal function tests and the severity markers of preeclampsia. Plasma endothelin-1 levels were determined in 45 serial plasma samples from 15 pregnant women who subsequently developed preeclampsia, and in 43 plasma samples from 25 women with uncomplicated pregnancies retrospectively. Renal function tests, complete blood counts, urinalysis and blood pressure measurements were performed during antenatal follow-ups of these patients. No correlations were set between plasma endothelin-1 levels and renal function tests, thrombocyte and white blood cell counts, proteinuria, systolic and diastolic blood pressures. There was no significant difference between the mean plasma  endothelin-1 concentrations of the preeclamptic and uncomplicated groups at all gestational weeks but at the time of delivery. None of the endothelin-1 values at any gestational week differed significantly from any other in the study group; therefore, the risk of subsequent development of preeclampsia could not be estimated by plasma endothelin-1 measurements.

Makale detayları

The Role of Plasma Endothelin-1 in Preeclampsia

Yazarlar:

Yalçın KİMYA

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 1999 Vol.29 Issue 1, pp.21-24

Belge Tipi:

Makale

Yayın Tarihi:

12/1998

Belge Dili:

Türkçe

Document ID (Org No.):

2000758119

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144

Endothelin-1

pregnancy

preeclampsia.

Sayı

Makale detayları

The Role of Plasma Endothelin-1 in Preeclampsia

Yazarlar: Yalçın KİMYA

Yayıncı: TUBITAK

Dergi: Turkish Journal of Medical Sciences 1999 Vol.29 Issue 1, pp.21-24

Belge Tipi: Makale

Yayın Tarihi: 12/1998

Belge Dili: Türkçe

Document ID (Org No.): 2000758119

Sıklık: İki Aylık

eISSN: 1303-6165

pISSN: 1300-0144

Endothelin-1

pregnancy

preeclampsia.

Sayı

Yazarlar:

Yalçın KİMYA

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 1999 Vol.29 Issue 1, pp.21-24

Belge Tipi:

Makale

Yayın Tarihi:

12/1998

Belge Dili:

Türkçe

Document ID (Org No.):

2000758119

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144