Phytochemical analysis and antioxidant evaluation of methanolic extracts from Lepidium sativum seeds and Averrhoa carambola fruits: A comparative analysis

Suchita Gupta

Makale detayları

Phytochemical analysis and antioxidant evaluation of methanolic extracts from Lepidium sativum seeds and Averrhoa carambola fruits: A comparative analysis

Yazarlar:

Suchita Gupta

Yayıncı:

İzzet KARA

Ana Başlıklar:

Pharmaceutical Biotechnology

Dergi:

International Journal of Secondary Metabolite Vol.12 Issue 3, pp.604-614

Belge Tipi:

Makale

Yayın Tarihi:

4/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001350187

pISSN:

2148-6905

Anahtar kelimeler:

Özet:

 This study compares the antioxidant potential and phytochemical composition of methanolic extracts from Lepidium sativum seeds and Averrhoa carambola fruits, chosen due to their traditional medicinal uses and differing plant parts, to explore their potential health benefits. The total phenolic content TPC, total flavonoid content, and various in vitro antioxidant assaysincluding 2,2-diphenyl-1-picrylhydrazyl DPPH radical scavenging, hydrogen peroxide scavenging, reducing power, superoxide dismutase SOD scavenger, and ferric thiocyanate testswere evaluated. The results revealed that Lepidium sativum exhibited significantly higher TPC 270.34 mggm and flavonoid content 85.05 mggm compared to Averrhoa carambola TPC: 49.04 mggm, flavonoids: 21.10 mggm. Additionally, Lepidium sativum consistently showed superior antioxidant efficacy across all assays, with higher inhibition percentages and lower inhibitory concentration 50 IC50 values for DPPH, hydrogen peroxide, and superoxide dismutase scavenging. The pronounced antioxidant activity of Lepidium sativum, likely due to its enriched phenolic and flavonoid content, highlights its potential as a natural remedy for managing oxidative stress-related diseases and warrants further investigation into its therapeutic applications for oxidative damage management.

 This study compares the antioxidant potential and phytochemical composition of methanolic extracts from Lepidium sativum seeds and Averrhoa carambola fruits, chosen due to their traditional medicinal uses and differing plant parts, to explore their potential health benefits. The total phenolic content TPC, total flavonoid content, and various in vitro antioxidant assaysincluding 2,2-diphenyl-1-picrylhydrazyl DPPH radical scavenging, hydrogen peroxide scavenging, reducing power, superoxide dismutase SOD scavenger, and ferric thiocyanate testswere evaluated. The results revealed that Lepidium sativum exhibited significantly higher TPC 270.34 mggm and flavonoid content 85.05 mggm compared to Averrhoa carambola TPC: 49.04 mggm, flavonoids: 21.10 mggm. Additionally, Lepidium sativum consistently showed superior antioxidant efficacy across all assays, with higher inhibition percentages and lower inhibitory concentration 50 IC50 values for DPPH, hydrogen peroxide, and superoxide dismutase scavenging. The pronounced antioxidant activity of Lepidium sativum, likely due to its enriched phenolic and flavonoid content, highlights its potential as a natural remedy for managing oxidative stress-related diseases and warrants further investigation into its therapeutic applications for oxidative damage management.

 This study compares the antioxidant potential and phytochemical composition of methanolic extracts from Lepidium sativum seeds and Averrhoa carambola fruits, chosen due to their traditional medicinal uses and differing plant parts, to explore their potential health benefits. The total phenolic content TPC, total flavonoid content, and various in vitro antioxidant assaysincluding 2,2-diphenyl-1-picrylhydrazyl DPPH radical scavenging, hydrogen peroxide scavenging, reducing power, superoxide dismutase SOD scavenger, and ferric thiocyanate testswere evaluated. The results revealed that Lepidium sativum exhibited significantly higher TPC 270.34 mggm and flavonoid content 85.05 mggm compared to Averrhoa carambola TPC: 49.04 mggm, flavonoids: 21.10 mggm. Additionally, Lepidium sativum consistently showed superior antioxidant efficacy across all assays, with higher inhibition percentages and lower inhibitory concentration 50 IC50 values for DPPH, hydrogen peroxide, and superoxide dismutase scavenging. The pronounced antioxidant activity of Lepidium sativum, likely due to its enriched phenolic and flavonoid content, highlights its potential as a natural remedy for managing oxidative stress-related diseases and warrants further investigation into its therapeutic applications for oxidative damage management.

 This study compares the antioxidant potential and phytochemical composition of methanolic extracts from Lepidium sativum seeds and Averrhoa carambola fruits, chosen due to their traditional medicinal uses and differing plant parts, to explore their potential health benefits. The total phenolic content TPC, total flavonoid content, and various in vitro antioxidant assaysincluding 2,2-diphenyl-1-picrylhydrazyl DPPH radical scavenging, hydrogen peroxide scavenging, reducing power, superoxide dismutase SOD scavenger, and ferric thiocyanate testswere evaluated. The results revealed that Lepidium sativum exhibited significantly higher TPC 270.34 mggm and flavonoid content 85.05 mggm compared to Averrhoa carambola TPC: 49.04 mggm, flavonoids: 21.10 mggm. Additionally, Lepidium sativum consistently showed superior antioxidant efficacy across all assays, with higher inhibition percentages and lower inhibitory concentration 50 IC50 values for DPPH, hydrogen peroxide, and superoxide dismutase scavenging. The pronounced antioxidant activity of Lepidium sativum, likely due to its enriched phenolic and flavonoid content, highlights its potential as a natural remedy for managing oxidative stress-related diseases and warrants further investigation into its therapeutic applications for oxidative damage management.

Makale detayları

Phytochemical analysis and antioxidant evaluation of methanolic extracts from Lepidium sativum seeds and Averrhoa carambola fruits: A comparative analysis

Yazarlar:

Suchita Gupta

Yayıncı:

İzzet KARA

Ana Başlıklar:

Pharmaceutical Biotechnology

Dergi:

International Journal of Secondary Metabolite Vol.12 Issue 3, pp.604-614

Belge Tipi:

Makale

Yayın Tarihi:

4/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001350187

pISSN:

2148-6905

Oxidative stress

Antioxidants

Lepidium sativum

Averrhoa carambola

Hydrogen peroxide

Oxidative damageOxidative stress

Antioxidants

Lepidium sativum

Averrhoa carambola

Hydrogen peroxide

Oxidative damage

Sayı

Makale detayları

Yazarlar: Suchita Gupta

Yayıncı: İzzet KARA

Ana Başlıklar: Pharmaceutical Biotechnology

Dergi: International Journal of Secondary Metabolite Vol.12 Issue 3, pp.604-614

Belge Tipi: Makale

Yayın Tarihi: 4/2025

Belge Dili: İngilizce

Document ID (Org No.): 2001350187

pISSN: 2148-6905

Sayı

Yazarlar:

Suchita Gupta

Yayıncı:

İzzet KARA

Ana Başlıklar:

Pharmaceutical Biotechnology

Dergi:

International Journal of Secondary Metabolite Vol.12 Issue 3, pp.604-614

Belge Tipi:

Makale

Yayın Tarihi:

4/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001350187

pISSN:

2148-6905