Usefulness of the neutrophil-to-lymphocyte ratio to prediction of complications in type 2 diabetes mellitus

Abdulhalim SENYİGİT

doi:https://doi.org/10.7197/223.vi.470380

Makale detayları

Usefulness of the neutrophil-to-lymphocyte ratio to prediction of complications in type 2 diabetes mellitus

Yazarlar:

Abdulhalim SENYİGİT

Ana Başlıklar:

Sağlık teşvikleri

Dergi:

Cumhuriyet Medical Journal 2018 Vol.40 Issue 4, pp.400-407

Belge Tipi:

Makale

Yayın Tarihi:

12/2018

Belge Dili:

İngilizce

Document ID (Org No.):

2000922669

DOI:

https://doi.org/10.7197/223.vi.470380

Özet:

 


Introduction:
Increasing evidences show that the concept of type 2 diabetes
mellitus (T2DM) as an inflammatory disease has emerged. The aim of the present
study was to investigate the role of neutrophil-to-lymphocyte ratio (NLR) in
T2DM patients comparing with the other well-known inflammatory markers as C-reactive
protein (CRP), erythrocyte sedimentation rate (ESR) and fibrinogen. It also
investigates usefulness of the NLR to prediction of complications in T2DM. Methods: This study consisted of six
patients groups in XXXXXX Hospital between April-October, 2017: It enrolled the
laboratory results of 195 subjects of which diabetic group (DM) (n=35), coronary
artery disease (CAD) group (n=35), CAD+DM group (n=35), DM+nephropathy (n=30),
DM+neuropathy (n=30), DM+retinopathy (n=30), and 40 healthy controls. Results: The mean NLR values were significantly higher in all
patients than controls. CAD+DM
group has the highest NLR values (4.17±3.85) among the
groups. There was no significant difference between the DM+nephropathy,
DM+neuropathy, and DM+retinopathy. The mean NLR values were significantly
higher in CAD+ DM group than DM+nephropathy, DM+neuropathy, and DM+retinopathy (for each comparison p<0.01).
 There was no statistically significant difference
in the mean NLR values between CAD group and CAD+DM group. Conclusion: Results of study demonstrate a possible association of
subclinical inflammation with the development of complications in T2DM. NLR is independently associated with other
well-known inflammatory markers as CRP, ESR and fibrinogen, inflammation in
development of complications in T2DM. NLR values in prediction of complications
in T2DM are a useful parameter. During complications of T2DM, NLR may be useful used as an easily measurable, noninvasive,
available and cost-effective parameter in clinical practice.






 

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Makale detayları

Usefulness of the neutrophil-to-lymphocyte ratio to prediction of complications in type 2 diabetes mellitus

Yazarlar: Abdulhalim SENYİGİT

Ana Başlıklar: Sağlık teşvikleri

Dergi: Cumhuriyet Medical Journal 2018 Vol.40 Issue 4, pp.400-407

Belge Tipi: Makale

Yayın Tarihi: 12/2018

Belge Dili: İngilizce

Document ID (Org No.): 2000922669

DOI: https://doi.org/10.7197/223.vi.470380

Sayı

Yazarlar:

Abdulhalim SENYİGİT

Ana Başlıklar:

Sağlık teşvikleri

Dergi:

Cumhuriyet Medical Journal 2018 Vol.40 Issue 4, pp.400-407

Belge Tipi:

Makale

Yayın Tarihi:

12/2018

Belge Dili:

İngilizce

Document ID (Org No.):

2000922669

DOI:

https://doi.org/10.7197/223.vi.470380