COMPARISON OF THE ANTIBACTERIAL EFFICIENCY OF SUPER ANIONIC OXYGEN SOLUTION CONTAINING SILVER NANOPARTICLES (NPAG) AND SUPER ANIONIC OXYGEN SOLUTION (H2O8) AGAINST E. FAECALIS AND S. MUTANS – AN IN VITRO STUDY

Damla Göçmen; Hilal Basak Erol; Fatma Gül Zıraman; Banu Kaşkatepe

Makale detayları

COMPARISON OF THE ANTIBACTERIAL EFFICIENCY OF SUPER ANIONIC OXYGEN SOLUTION CONTAINING SILVER NANOPARTICLES (NPAG) AND SUPER ANIONIC OXYGEN SOLUTION (H2O8) AGAINST E. FAECALIS AND S. MUTANS – AN IN VITRO STUDY

Yazarlar:

Damla Göçmen | Hilal Basak Erol | Fatma Gül Zıraman | Banu Kaşkatepe

Yayıncı:

Ankara University

Ana Başlıklar:

Farmasotik Mikrobiyoloji

Dergi:

Ankara Üniversitesi Eczacılık Fakültesi Dergisi Vol.49 Issue 3, pp.785-789

Belge Tipi:

Makale

Yayın Tarihi:

9/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001356405

pISSN:

1015-3918

Anahtar kelimeler:

Özet:

 Objective: The purpose of this study is to compare the antimicrobial effect of super anionic oxygen solution containing silver nanoparticles NpAg and super anionic oxygen solution H2O8 in vitro Material and Method: The antimicrobial activity of the solutions was tested against Enterococcus faecalis ATCC 29212 E. faecalis and Streptococcus mutans ATCC 25175 S. mutans standart bacteria. The effects of them applied on the bacterial suspension after 10 minutes were examined in terms of colony reduction. Result and Discussion: As a result of the efficacy tests, NpAg solution showed a 46.67 0.27 log decrease in E. faecalis concentration and a 58.8 0.38 log decrease in S. mutans concentration. Similarly, H2O8 solution showed an 84.67 0.81 log decrease in E. faecalis concentration and a 62.94 0.43 log decrease in S. mutans concentration. Under the limitations of this study, it was concluded that super anionic oxygen solutions NpAg and super anionic oxygen solutions H2O8 have a significant antimicrobial flora against E. faecalis and S. mutans, but are attenuated when compared to irrigants routinely used clinically. Since this study did not simulate the oral environment, future studies may provide more effective results.

 Objective: The purpose of this study is to compare the antimicrobial effect of super anionic oxygen solution containing silver nanoparticles NpAg and super anionic oxygen solution H2O8 in vitro Material and Method: The antimicrobial activity of the solutions was tested against Enterococcus faecalis ATCC 29212 E. faecalis and Streptococcus mutans ATCC 25175 S. mutans standart bacteria. The effects of them applied on the bacterial suspension after 10 minutes were examined in terms of colony reduction. Result and Discussion: As a result of the efficacy tests, NpAg solution showed a 46.67 0.27 log decrease in E. faecalis concentration and a 58.8 0.38 log decrease in S. mutans concentration. Similarly, H2O8 solution showed an 84.67 0.81 log decrease in E. faecalis concentration and a 62.94 0.43 log decrease in S. mutans concentration. Under the limitations of this study, it was concluded that super anionic oxygen solutions NpAg and super anionic oxygen solutions H2O8 have a significant antimicrobial flora against E. faecalis and S. mutans, but are attenuated when compared to irrigants routinely used clinically. Since this study did not simulate the oral environment, future studies may provide more effective results.

 Objective: The purpose of this study is to compare the antimicrobial effect of super anionic oxygen solution containing silver nanoparticles NpAg and super anionic oxygen solution H2O8 in vitro Material and Method: The antimicrobial activity of the solutions was tested against Enterococcus faecalis ATCC 29212 E. faecalis and Streptococcus mutans ATCC 25175 S. mutans standart bacteria. The effects of them applied on the bacterial suspension after 10 minutes were examined in terms of colony reduction. Result and Discussion: As a result of the efficacy tests, NpAg solution showed a 46.67 0.27 log decrease in E. faecalis concentration and a 58.8 0.38 log decrease in S. mutans concentration. Similarly, H2O8 solution showed an 84.67 0.81 log decrease in E. faecalis concentration and a 62.94 0.43 log decrease in S. mutans concentration. Under the limitations of this study, it was concluded that super anionic oxygen solutions NpAg and super anionic oxygen solutions H2O8 have a significant antimicrobial flora against E. faecalis and S. mutans, but are attenuated when compared to irrigants routinely used clinically. Since this study did not simulate the oral environment, future studies may provide more effective results.

 Amaç: Bu çalışmanın amacı gümüş nanopartikülleri içeren süper anyonik oksijen solüsyonu NpAg ile süper anyonik oksijen solüsyonu H2O8 antimikrobiyal etkisini karşılaştırmaktır. Gereç ve Yöntem: Solüsyonların antimikrobiyal aktivitesi Enterococcus faecalis ATCC 29212 E. faecalis ve Streptococcus mutans ATCC 25175 S. mutans standart bakterilere karşı test edilmiştir. Bakteri süspansiyonuna 10 dakika sonra uygulananların koloni azalması açısından etkileri incelenmiştir. Sonuç ve Tartışma: Yapılan etkinlik testleri sonucunda NpAg solüsyonu, E. faecalis konsantrasyonunda 46.67 0.27 log, S. mutans konsantrasyonunda ise 58.8 0.38 log azalma gösterdi. Benzer şekilde H2O8 solüsyonu, E. faecalis konsantrasyonunda 84.67 0.81 log azalma ve S. mutans konsantrasyonunda 62.94 0.43 log azalma gösterdi. Bu çalışmanın sınırlamaları altında, süper anyonik oksijen çözeltilerinin NpAg ve süper anyonik oksijen çökeltilerinin H2O8 E. faecalis ve S. mutansa karşı önemli bir antimikrobiyal etkiye sahip olduğu ancak klinikte rutin olarak kullanılan irrigasyonlarla karşılaştırıldığında zayıf kaldığı sonucuna varılmıştır. Bu çalışma ağız ortamını simüle etmediği için gelecekteki çalışmalar daha etkili sonuçlar verebilir.

Makale detayları

COMPARISON OF THE ANTIBACTERIAL EFFICIENCY OF SUPER ANIONIC OXYGEN SOLUTION CONTAINING SILVER NANOPARTICLES (NPAG) AND SUPER ANIONIC OXYGEN SOLUTION (H2O8) AGAINST E. FAECALIS AND S. MUTANS – AN IN VITRO STUDY

Yazarlar:

Damla Göçmen | Hilal Basak Erol | Fatma Gül Zıraman | Banu Kaşkatepe

Yayıncı:

Ankara University

Ana Başlıklar:

Farmasotik Mikrobiyoloji

Dergi:

Ankara Üniversitesi Eczacılık Fakültesi Dergisi Vol.49 Issue 3, pp.785-789

Belge Tipi:

Makale

Yayın Tarihi:

9/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001356405

pISSN:

1015-3918

Biofilms

dentin

endodontics

nanoparticles

root canal irrigantsBiofilm

dentin

endodonti

kök kanal irrigasyonu

nanopartikül

Sayı

Makale detayları

Yazarlar: Damla Göçmen | Hilal Basak Erol | Fatma Gül Zıraman | Banu Kaşkatepe

Yayıncı: Ankara University

Ana Başlıklar: Farmasotik Mikrobiyoloji

Dergi: Ankara Üniversitesi Eczacılık Fakültesi Dergisi Vol.49 Issue 3, pp.785-789

Belge Tipi: Makale

Yayın Tarihi: 9/2025

Belge Dili: İngilizce

Document ID (Org No.): 2001356405

pISSN: 1015-3918

Sayı

Yazarlar:

Damla Göçmen | Hilal Basak Erol | Fatma Gül Zıraman | Banu Kaşkatepe

Yayıncı:

Ankara University

Ana Başlıklar:

Farmasotik Mikrobiyoloji

Dergi:

Ankara Üniversitesi Eczacılık Fakültesi Dergisi Vol.49 Issue 3, pp.785-789

Belge Tipi:

Makale

Yayın Tarihi:

9/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001356405

pISSN:

1015-3918