Effect of Additional Prebiotics on Glycemia and Lipid Profile in Individuals with Type 2 Diabetes

Ayşe Ayda Demirtaş; Nilüfer Acar Tek

Makale detayları

Effect of Additional Prebiotics on Glycemia and Lipid Profile in Individuals with Type 2 Diabetes

Yazarlar:

Ayşe Ayda Demirtaş | Nilüfer Acar Tek

Yayıncı:

Gazi University

Ana Başlıklar:

Clinical Sciences (Other)

Dergi:

Journal of Gazi University Health Sciences Institute Vol.6 Issue 1, pp.1-10

Belge Tipi:

Makale

Yayın Tarihi:

4/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001316740

pISSN:

2687-6353

Anahtar kelimeler:

Özet:

 This study was conducted to determine the effect of prebiotic fiber intake on glycemia and lipemia in individuals with Type 2 Diabetes Mellitus Type 2 DM. Over a 8-week period, 14 individuals with Type 2 DM between the ages of 20-50 with a Body Mass Index BMI above 25 kgm² were randomly assigned to either an intervention group, in which participants were given additional prebiotic fiber with diabetic diet n  8, consuming 10 gd of oligofructose-enriched inulin to diabetic diet or to a control group, in which participants were given only with a diabetic diet n  6, consuming only diabetic diet. Fasting Plasma Glucose FPG, fasting insulin, insulin resistance HOMA-IR, glycosylated hemoglobin HbA1c, Triglyceride TG, Total Cholesterol Total-C, High-Density Lipoprotein Cholesterol HDL-C, Low-Density Lipoprotein Cholesterol LDL-C and Very Low-Density Lipoprotein Cholesterol VLDL-C values were measured at the beginning and end of the study. There was no significant difference between the initial and last measurements in HbA1c, fasting insulin, HOMA-IR, and HDL-C values only in the diabetic diet group p0.05; whereas FPG, TG, Total-C, LDL-C, and VLDL-C levels decreased p0.05. In the group that received additional prebiotics in the diet, the FPG, HbA1c, TG, Total-C, VLDL-C, and LDL-C levels decreased significantly p0.05 at the end of the study compared to the beginning; HDL-C p0.05 was elevated. Prebiotics can be used as a new option in the treatment of many metabolic diseases, especially diabetes. Prebiotics will make a positive contribution to metabolic markers by changing the composition of the microbiota.

 This study was conducted to determine the effect of prebiotic fiber intake on glycemia and lipemia in individuals with Type 2 Diabetes Mellitus Type 2 DM. Over a 8-week period, 14 individuals with Type 2 DM between the ages of 20-50 with a Body Mass Index BMI above 25 kgm² were randomly assigned to either an intervention group, in which participants were given additional prebiotic fiber with diabetic diet n  8, consuming 10 gd of oligofructose-enriched inulin to diabetic diet or to a control group, in which participants were given only with a diabetic diet n  6, consuming only diabetic diet. Fasting Plasma Glucose FPG, fasting insulin, insulin resistance HOMA-IR, glycosylated hemoglobin HbA1c, Triglyceride TG, Total Cholesterol Total-C, High-Density Lipoprotein Cholesterol HDL-C, Low-Density Lipoprotein Cholesterol LDL-C and Very Low-Density Lipoprotein Cholesterol VLDL-C values were measured at the beginning and end of the study. There was no significant difference between the initial and last measurements in HbA1c, fasting insulin, HOMA-IR, and HDL-C values only in the diabetic diet group p0.05; whereas FPG, TG, Total-C, LDL-C, and VLDL-C levels decreased p0.05. In the group that received additional prebiotics in the diet, the FPG, HbA1c, TG, Total-C, VLDL-C, and LDL-C levels decreased significantly p0.05 at the end of the study compared to the beginning; HDL-C p0.05 was elevated. Prebiotics can be used as a new option in the treatment of many metabolic diseases, especially diabetes. Prebiotics will make a positive contribution to metabolic markers by changing the composition of the microbiota.

 This study was conducted to determine the effect of prebiotic fiber intake on glycemia and lipemia in individuals with Type 2 Diabetes Mellitus Type 2 DM. Over a 8-week period, 14 individuals with Type 2 DM between the ages of 20-50 with a Body Mass Index BMI above 25 kgm² were randomly assigned to either an intervention group, in which participants were given additional prebiotic fiber with diabetic diet n  8, consuming 10 gd of oligofructose-enriched inulin to diabetic diet or to a control group, in which participants were given only with a diabetic diet n  6, consuming only diabetic diet. Fasting Plasma Glucose FPG, fasting insulin, insulin resistance HOMA-IR, glycosylated hemoglobin HbA1c, Triglyceride TG, Total Cholesterol Total-C, High-Density Lipoprotein Cholesterol HDL-C, Low-Density Lipoprotein Cholesterol LDL-C and Very Low-Density Lipoprotein Cholesterol VLDL-C values were measured at the beginning and end of the study. There was no significant difference between the initial and last measurements in HbA1c, fasting insulin, HOMA-IR, and HDL-C values only in the diabetic diet group p0.05; whereas FPG, TG, Total-C, LDL-C, and VLDL-C levels decreased p0.05. In the group that received additional prebiotics in the diet, the FPG, HbA1c, TG, Total-C, VLDL-C, and LDL-C levels decreased significantly p0.05 at the end of the study compared to the beginning; HDL-C p0.05 was elevated. Prebiotics can be used as a new option in the treatment of many metabolic diseases, especially diabetes. Prebiotics will make a positive contribution to metabolic markers by changing the composition of the microbiota.

 This study was conducted to determine the effect of prebiotic fiber intake on glycemia and lipemia in individuals with Type 2 Diabetes Mellitus Type 2 DM. Over a 8-week period, 14 individuals with Type 2 DM between the ages of 20-50 with a Body Mass Index BMI above 25 kgm² were randomly assigned to either an intervention group, in which participants were given additional prebiotic fiber with diabetic diet n  8, consuming 10 gd of oligofructose-enriched inulin to diabetic diet or to a control group, in which participants were given only with a diabetic diet n  6, consuming only diabetic diet. Fasting Plasma Glucose FPG, fasting insulin, insulin resistance HOMA-IR, glycosylated hemoglobin HbA1c, Triglyceride TG, Total Cholesterol Total-C, High-Density Lipoprotein Cholesterol HDL-C, Low-Density Lipoprotein Cholesterol LDL-C and Very Low-Density Lipoprotein Cholesterol VLDL-C values were measured at the beginning and end of the study. There was no significant difference between the initial and last measurements in HbA1c, fasting insulin, HOMA-IR, and HDL-C values only in the diabetic diet group p0.05; whereas FPG, TG, Total-C, LDL-C, and VLDL-C levels decreased p0.05. In the group that received additional prebiotics in the diet, the FPG, HbA1c, TG, Total-C, VLDL-C, and LDL-C levels decreased significantly p0.05 at the end of the study compared to the beginning; HDL-C p0.05 was elevated. Prebiotics can be used as a new option in the treatment of many metabolic diseases, especially diabetes. Prebiotics will make a positive contribution to metabolic markers by changing the composition of the microbiota.

Makale detayları

Effect of Additional Prebiotics on Glycemia and Lipid Profile in Individuals with Type 2 Diabetes

Yazarlar:

Ayşe Ayda Demirtaş | Nilüfer Acar Tek

Yayıncı:

Gazi University

Ana Başlıklar:

Clinical Sciences (Other)

Dergi:

Journal of Gazi University Health Sciences Institute Vol.6 Issue 1, pp.1-10

Belge Tipi:

Makale

Yayın Tarihi:

4/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001316740

pISSN:

2687-6353

gycemic control

lipemia

prebiotic

Type 2 diabetes

Sayı

Makale detayları

Effect of Additional Prebiotics on Glycemia and Lipid Profile in Individuals with Type 2 Diabetes

Yazarlar: Ayşe Ayda Demirtaş | Nilüfer Acar Tek

Yayıncı: Gazi University

Ana Başlıklar: Clinical Sciences (Other)

Dergi: Journal of Gazi University Health Sciences Institute Vol.6 Issue 1, pp.1-10

Belge Tipi: Makale

Yayın Tarihi: 4/2024

Belge Dili: İngilizce

Document ID (Org No.): 2001316740

pISSN: 2687-6353

gycemic control

lipemia

prebiotic

Type 2 diabetes

Sayı

Yazarlar:

Ayşe Ayda Demirtaş | Nilüfer Acar Tek

Yayıncı:

Gazi University

Ana Başlıklar:

Clinical Sciences (Other)

Dergi:

Journal of Gazi University Health Sciences Institute Vol.6 Issue 1, pp.1-10

Belge Tipi:

Makale

Yayın Tarihi:

4/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001316740

pISSN:

2687-6353